iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117853

UUCD1 version

UUC-TaR-00214

Ensembl Protein ID

ENSTRUP00000015636.1

UniProt Accession

H2ST99; H2ST99_TAKRU

Protein Name

Uncharacterized protein

Gene Name

TRAF2 (1 of many)

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000006395.1	ENSTRUT00000015701.1	ENSTRUP00000015632.1
ENSTRUG00000006395.1	ENSTRUT00000015702.1	ENSTRUP00000015633.1
ENSTRUG00000006395.1	ENSTRUT00000015703.1	ENSTRUP00000015634.1
ENSTRUG00000006395.1	ENSTRUT00000015704.1	ENSTRUP00000015635.1
ENSTRUG00000006395.1	ENSTRUT00000015705.1	ENSTRUP00000015636.1
ENSTRUG00000006395.1	ENSTRUT00000015706.1	ENSTRUP00000015637.1
ENSTRUG00000006395.1	ENSTRUT00000015707.1	ENSTRUP00000015638.1
ENSTRUG00000006395.1	ENSTRUT00000015708.1	ENSTRUP00000015639.1
ENSTRUG00000006395.1	ENSTRUT00000015709.1	ENSTRUP00000015640.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	62.14	0.00e+00	691.00	IUUC-Hsa-046952

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

TQEPSPPSSM ESNKPGFPKK ILGNKLEDKH LCNCCHNILR RPFQAQCGHR FCSYCFNRTV 60
SNGPQKCSAC IKEDIFEDPT SILKQGCAFP DNAVRREVEH LPAACINENC TWKGTIKEYE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAGACGCCA TGGCCACACA GGAGCCGTCC CCTCCTTCGT CCATGGAGAG CAACAAGCCC 60
GGCTTCCCCA AGAAGATCCT GGGCAACAAG CTGGAGGACA AACACCTGTG CAACTGCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027133--TRAF2
IPR032070--TRAF_BIRC3-bd
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF16673--TRAF_BIRC3_bd
PF02176--zf-TRAF

SMART

SM00061--MATH

Gene Ontology

GO:0005622--C:intracellular
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0051865--P:protein autoubiquitination
GO:0042981--P:regulation of apoptotic process
GO:0046328--P:regulation of JNK cascade
GO:0033209--P:tumor necrosis factor-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002344	Ailuropoda melanoleuca	62.79	0.00e+00	688.00
IUUC-Apl-004202	Anas platyrhynchos	63.60	0.00e+00	719.00
IUUC-Aca-005029	Anolis carolinensis	43.36	7.00e-97	347.00
IUUC-Ame-011841	Astyanax mexicanus	70.70	0.00e+00	816.00
IUUC-Bta-013180	Bos taurus	60.11	0.00e+00	669.00
IUUC-Cja-019813	Callithrix jacchus	61.52	0.00e+00	689.00
IUUC-Cfa-021205	Canis familiaris	62.91	0.00e+00	674.00
IUUC-Cpo-021346	Cavia porcellus	61.19	0.00e+00	686.00
IUUC-Csa-023809	Chlorocebus sabaeus	62.53	2.00e-177	614.00
IUUC-Dre-027669	Danio rerio	59.46	4.00e-180	624.00
IUUC-Dno-029458	Dasypus novemcinctus	61.64	0.00e+00	689.00
IUUC-Dor-030338	Dipodomys ordii	59.46	2.00e-176	611.00
IUUC-Ete-032910	Echinops telfairi	32.71	8.00e-76	278.00
IUUC-Eca-034401	Equus caballus	61.52	0.00e+00	688.00
IUUC-Eeu-034668	Erinaceus europaeus	75.00	1.00e-69	257.00
IUUC-Fca-036057	Felis catus	62.24	0.00e+00	697.00
IUUC-Fal-037560	Ficedula albicollis	58.03	6.00e-179	620.00
IUUC-Gmo-038964	Gadus morhua	74.86	0.00e+00	801.00
IUUC-Gga-040425	Gallus gallus	64.12	0.00e+00	712.00
IUUC-Gac-041908	Gasterosteus aculeatus	75.66	0.00e+00	818.00
IUUC-Ggo-044606	Gorilla gorilla	55.64	1.00e-175	608.00
IUUC-Hsa-046952	Homo sapiens	61.95	0.00e+00	694.00
IUUC-Itr-049016	Ictidomys tridecemlineatus	55.13	3.00e-171	594.00
IUUC-Lch-049571	Latimeria chalumnae	58.71	0.00e+00	689.00
IUUC-Loc-051973	Lepisosteus oculatus	62.77	0.00e+00	645.00
IUUC-Laf-053815	Loxodonta africana	61.57	0.00e+00	670.00
IUUC-Mcc-054888	Macaca mulatta	62.14	0.00e+00	691.00
IUUC-Meu-056547	Macropus eugenii	56.22	8.00e-152	530.00
IUUC-Mga-059819	Meleagris gallopavo	62.10	0.00e+00	677.00
IUUC-Mdo-062570	Monodelphis domestica	62.81	0.00e+00	709.00
IUUC-Mmu-063133	Mus musculus	59.85	0.00e+00	655.00
IUUC-Mpu-065802	Mustela putorius furo	62.71	0.00e+00	697.00
IUUC-Nle-070155	Nomascus leucogenys	62.14	0.00e+00	695.00
IUUC-Opr-070856	Ochotona princeps	57.09	2.00e-78	286.00
IUUC-Ont-071930	Oreochromis niloticus	89.58	0.00e+00	969.00
IUUC-Ola-087397	Oryzias latipes	86.43	0.00e+00	951.00
IUUC-Oga-088109	Otolemur garnettii	61.14	0.00e+00	691.00
IUUC-Oar-090310	Ovis aries	54.81	7.00e-171	593.00
IUUC-Ptr-090643	Pan troglodytes	61.95	0.00e+00	695.00
IUUC-Pan-091933	Papio anubis	61.76	0.00e+00	689.00
IUUC-Psi-093681	Pelodiscus sinensis	63.26	0.00e+00	688.00
IUUC-Pfo-096148	Poecilia formosa	88.41	0.00e+00	964.00
IUUC-Pab-098631	Pongo abelii	61.90	0.00e+00	697.00
IUUC-Pca-100582	Procavia capensis	54.82	4.00e-67	248.00
IUUC-Pva-102396	Pteropus vampyrus	52.96	2.00e-156	545.00
IUUC-Rno-106120	Rattus norvegicus	55.26	2.00e-172	598.00
IUUC-Sha-106493	Sarcophilus harrisii	63.00	0.00e+00	709.00
IUUC-Sar-113570	Sorex araneus	80.66	5.00e-90	324.00
IUUC-Ssc-115843	Sus scrofa	60.80	0.00e+00	685.00
IUUC-Tgu-117144	Taeniopygia guttata	56.55	7.00e-170	590.00
IUUC-Tni-120256	Tetraodon nigroviridis	90.89	0.00e+00	983.00
IUUC-Tbe-127943	Tupaia belangeri	48.00	1.00e-74	273.00
IUUC-Ttr-129246	Tursiops truncatus	60.99	0.00e+00	668.00
IUUC-Xtr-132279	Xenopus tropicalis	54.49	1.00e-160	559.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence