iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cja-019686

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACFV01067967

Gene Name

SH3RF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000021336.2	ENSCJAT00000041968.2	ENSCJAP00000039725.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	7.60e-08	33.7	12	53
UBD/SH3	9.80e-30	103.3	383	437

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++C+e ++   +vlpC+H+f++ Clq++     ++ ke rCP Cr
   Q: 12   CPVCFEKLDVTAKVLPCQHTFCKPCLQRV----FKAHKELRCPECR 53
           ********88899****************....99**********8 PP

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           + + +l++y+a   deL l++G+ ++v+  ++qd gWl+gv+  +g+ G+fP+n+v 
   Q: 383  NMFVALHSYSAHGPDELDLQRGEGIRVL-GKCQD-GWLRGVSLVTGRVGIFPNNYVI 437
           7889************************.77776.9*******************96 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MDDLTLLDLL ECPVCFEKLD VTAKVLPCQH TFCKPCLQRV FKAHKELRCP ECRTPVFCSI 60
EALPANLLLV RLLDGVRSGQ SSGRGGSFRR PGTMTLQDSR KSRTNPRRLQ ASPFRLVPNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATGATT TGACGTTACT TGATCTTCTG GAGTGCCCTG TGTGCTTTGA GAAGCTCGAT 60
GTCACGGCCA AAGTCCTCCC TTGCCAGCAC ACCTTCTGCA AACCATGTCT ACAGAGGGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011511--SH3_2
IPR001452--SH3_domain
IPR028511--SH3RF2
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9
PF13445--zf-RING_UBOX

PRINTS

PR00452--SH3DOMAIN

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008270--F:zinc ion binding
GO:0010923--P:negative regulation of phosphatase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001594	Ailuropoda melanoleuca	76.02	0.00e+00	961.00
IUUC-Apl-003443	Anas platyrhynchos	66.90	4.00e-154	538.00
IUUC-Aca-004632	Anolis carolinensis	57.84	5.00e-147	514.00
IUUC-Bta-013400	Bos taurus	76.88	0.00e+00	927.00
IUUC-Cel-018180	Caenorhabditis elegans	28.11	2.00e-23	104.00
IUUC-Cfa-020893	Canis familiaris	77.90	0.00e+00	980.00
IUUC-Cpo-021638	Cavia porcellus	73.17	0.00e+00	931.00
IUUC-Csa-023846	Chlorocebus sabaeus	81.22	0.00e+00	1039.00
IUUC-Cho-024609	Choloepus hoffmanni	86.32	9.00e-164	570.00
IUUC-Dno-028940	Dasypus novemcinctus	74.52	0.00e+00	927.00
IUUC-Dor-030491	Dipodomys ordii	89.50	4.00e-109	389.00
IUUC-Dse-031414	Dothistroma septosporum	32.84	1.00e-07	52.00
IUUC-Ete-032513	Echinops telfairi	74.35	0.00e+00	937.00
IUUC-Eca-034241	Equus caballus	77.58	0.00e+00	992.00
IUUC-Eeu-034636	Erinaceus europaeus	72.73	0.00e+00	846.00
IUUC-Fca-035862	Felis catus	74.35	0.00e+00	934.00
IUUC-Gga-040748	Gallus gallus	58.47	3.00e-124	439.00
IUUC-Ggo-045267	Gorilla gorilla	81.63	0.00e+00	1063.00
IUUC-Hsa-045761	Homo sapiens	81.84	0.00e+00	1062.00
IUUC-Itr-048226	Ictidomys tridecemlineatus	85.66	0.00e+00	840.00
IUUC-Lch-050498	Latimeria chalumnae	53.93	3.00e-113	402.00
IUUC-Laf-054061	Loxodonta africana	64.57	0.00e+00	690.00
IUUC-Mcc-054746	Macaca mulatta	81.48	0.00e+00	1029.00
IUUC-Meu-056390	Macropus eugenii	45.14	4.00e-58	219.00
IUUC-Mmr-061390	Microcebus murinus	74.38	0.00e+00	792.00
IUUC-Mdo-062951	Monodelphis domestica	64.50	0.00e+00	852.00
IUUC-Mmu-063840	Mus musculus	70.29	0.00e+00	887.00
IUUC-Mpu-065840	Mustela putorius furo	75.55	0.00e+00	976.00
IUUC-Mlu-067378	Myotis lucifugus	73.81	0.00e+00	900.00
IUUC-Nle-069535	Nomascus leucogenys	82.36	0.00e+00	1009.00
IUUC-Opr-070739	Ochotona princeps	71.31	0.00e+00	900.00
IUUC-Oan-073468	Ornithorhynchus anatinus	60.03	0.00e+00	710.00
IUUC-Ocu-074343	Oryctolagus cuniculus	74.90	0.00e+00	922.00
IUUC-Oga-088276	Otolemur garnettii	70.58	0.00e+00	890.00
IUUC-Oar-090315	Ovis aries	74.97	0.00e+00	916.00
IUUC-Ptr-091119	Pan troglodytes	82.08	0.00e+00	1057.00
IUUC-Pan-092158	Papio anubis	95.53	0.00e+00	894.00
IUUC-Psi-092959	Pelodiscus sinensis	65.98	0.00e+00	630.00
IUUC-Pab-097675	Pongo abelii	81.77	0.00e+00	1048.00
IUUC-Pca-101021	Procavia capensis	68.49	0.00e+00	836.00
IUUC-Pva-102619	Pteropus vampyrus	76.72	0.00e+00	919.00
IUUC-Rno-105918	Rattus norvegicus	70.43	0.00e+00	896.00
IUUC-Sha-107391	Sarcophilus harrisii	61.62	0.00e+00	778.00
IUUC-Sja-107661	Schizosaccharomyces japonicus	44.83	3.00e-10	59.70
IUUC-Sar-113148	Sorex araneus	81.15	0.00e+00	637.00
IUUC-Ssc-116219	Sus scrofa	59.09	3.00e-87	315.00
IUUC-Tgu-116584	Taeniopygia guttata	56.25	1.00e-108	385.00
IUUC-Tsy-118968	Tarsius syrichta	84.72	3.00e-166	578.00
IUUC-Tbe-128007	Tupaia belangeri	91.00	0.00e+00	821.00
IUUC-Ttr-128499	Tursiops truncatus	74.00	0.00e+00	939.00
IUUC-Vpa-130075	Vicugna pacos	95.08	5.00e-70	258.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence