iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052025

Ensembl Protein ID

ENSLOCP00000003143.1

UniProt Accession

W5M435; W5M435_LEPOC

Genbank Protein ID

ENSLOCP00000003143

Protein Name

Phosphoinositide phospholipase C

Genbank Nucleotide ID

AHAT01010611

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000002618.1	ENSLOCT00000003150.1	ENSLOCP00000003143.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.80e-12	47.2	777	834

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrG.lfPenFvekle 63
           k++v++lydy a  +deL++ kG  ++ +   ++d+gW+kg  +  gk   +fP+n+ve+++
   Q: 777  KNTVKALYDYRAMRSDELNFCKGALIHNV--VKEDGGWWKG--DYGGKVQlFFPSNYVEEVS 834
           789************************99..899*******..6776665168******996 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MDMLSCGTMA GVSSITNMTE YQKSSIKREL EMGIVMTVFR QKVERLTVQV IMETRQIAWT 60
RTSDKYEGVL DLHEIREIRP GKNFKDFERF KERCLDETTC FTIFYGSQFV LNTLSLSADN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGCTGGTTC CCAGATGAAA GGGTCTAAAC CTGTTTGTCC ACAACTACAG GGTATTGAAT 60
GGACATGGTA AGTTTGGTTT CCTTAGTCAA CAAAAGGGAC TAAAACAATT TCTAAGAGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0442--Lipid degradation
KW-0443--Lipid metabolism
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0807--Transducer

Interpro

IPR000008--C2_dom
IPR011992--EF-hand-dom_pair
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001192--PI-PLC_fam
IPR016279--PLC-gamma
IPR028381--PLC-gamma2
IPR017946--PLC-like_Pdiesterase_TIM-brl
IPR000909--PLipase_C_PInositol-sp_X_dom
IPR001711--PLipase_C_Pinositol-sp_Y
IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS50007--PIPLC_X_DOMAIN
PS50008--PIPLC_Y_DOMAIN
PS50001--SH2
PS50002--SH3

Pfam

PF00168--C2
PF00388--PI-PLC-X
PF00387--PI-PLC-Y
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00390--PHPHLIPASEC
PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00233--PH
SM00148--PLCXc
SM00149--PLCYc
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0004435--F:phosphatidylinositol phospholipase C activity
GO:0004871--F:signal transducer activity
GO:0035556--P:intracellular signal transduction
GO:0009395--P:phospholipid catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003345	Anas platyrhynchos	65.10	0.00e+00	1569.00
IUUC-Aca-004266	Anolis carolinensis	62.91	0.00e+00	1645.00
IUUC-Ame-011540	Astyanax mexicanus	68.99	0.00e+00	1709.00
IUUC-Bta-013196	Bos taurus	62.54	0.00e+00	1580.00
IUUC-Cpo-021890	Cavia porcellus	61.28	0.00e+00	1614.00
IUUC-Csa-024233	Chlorocebus sabaeus	61.60	0.00e+00	1628.00
IUUC-Dre-028650	Danio rerio	69.24	0.00e+00	1731.00
IUUC-Dno-028871	Dasypus novemcinctus	62.24	0.00e+00	1590.00
IUUC-Eca-033458	Equus caballus	61.99	0.00e+00	1626.00
IUUC-Eeu-035329	Erinaceus europaeus	58.45	0.00e+00	1515.00
IUUC-Fal-037390	Ficedula albicollis	64.33	0.00e+00	1674.00
IUUC-Gga-040918	Gallus gallus	64.17	0.00e+00	1665.00
IUUC-Ggo-045625	Gorilla gorilla	60.66	0.00e+00	1597.00
IUUC-Hsa-046129	Homo sapiens	61.76	0.00e+00	1634.00
IUUC-Mcc-054831	Macaca mulatta	61.93	0.00e+00	1584.00
IUUC-Mga-059368	Meleagris gallopavo	64.65	0.00e+00	1649.00
IUUC-Mmr-060898	Microcebus murinus	60.18	0.00e+00	1474.00
IUUC-Mmu-064334	Mus musculus	61.68	0.00e+00	1622.00
IUUC-Mlu-067230	Myotis lucifugus	62.10	0.00e+00	1626.00
IUUC-Nle-069318	Nomascus leucogenys	57.19	0.00e+00	1464.00
IUUC-Opr-070718	Ochotona princeps	54.80	0.00e+00	734.00
IUUC-Ocu-073814	Oryctolagus cuniculus	61.55	0.00e+00	1618.00
IUUC-Ola-086501	Oryzias latipes	68.11	0.00e+00	1757.00
IUUC-Oar-089556	Ovis aries	62.12	0.00e+00	1570.00
IUUC-Ptr-091001	Pan troglodytes	61.83	0.00e+00	1636.00
IUUC-Pan-092744	Papio anubis	61.68	0.00e+00	1624.00
IUUC-Psi-093987	Pelodiscus sinensis	64.52	0.00e+00	1682.00
IUUC-Pfo-096249	Poecilia formosa	69.24	0.00e+00	1777.00
IUUC-Pab-098268	Pongo abelii	60.89	0.00e+00	1601.00
IUUC-Pva-102939	Pteropus vampyrus	60.34	0.00e+00	1509.00
IUUC-Ssc-115308	Sus scrofa	59.90	0.00e+00	1430.00
IUUC-Tgu-116811	Taeniopygia guttata	63.86	0.00e+00	1666.00
IUUC-Tru-117536	Takifugu rubripes	67.24	0.00e+00	1689.00
IUUC-Tsy-119139	Tarsius syrichta	55.15	0.00e+00	635.00
IUUC-Ttr-128392	Tursiops truncatus	59.14	0.00e+00	1544.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence