iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-065907

Ensembl Protein ID

ENSMPUP00000000977.1

UniProt Accession

M3XPH7; M3XPH7_MUSPF

Genbank Protein ID

ENSMPUP00000000977

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01084944

Gene Name

OPTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000000984.1	ENSMPUT00000000997.1	ENSMPUP00000000977.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	7.90e-24	83.4	460	516

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklndsl 57
           +ee+let++vL++Q+e+Y++DF+aERa+RE+++eeke+L+ q+++l+k+ + ++d+ 
   Q: 460  QEEDLETMTVLRAQMEVYCSDFHAERAAREKIHEEKEQLALQLAVLLKEDNVFEDGS 516
           79***************************************************9974 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MSHQPLSCLT EKGDSPNETT GNGPPNLAHP NLDTFTPEEL LRQMKELLTE NHQLKEAMKL 60
NNQAMKGRFE ELSAWTEKQK EERLFFEIQS KEAKERLMAL SHENEKLKEK LEKLKGKMEK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCGACTGCG GGGCGGGGCC TGGGAAATTC CCGGCGGGGG CAGGGAGGCC CGCGCGGCGG 60
TCAGCTGAGC GGCGCTGGGC GGGGTCGCGA GGCCGCAAGT CAGCCCGAGG CTCAGCGAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR021063--NEMO_N
IPR032939--Optineurin
IPR034735--ZF_CCHC_NOA

PROSITE

PS51801--ZF_CCHC_NOA

Pfam

PF16516--CC2-LZ
PF11577--NEMO

Gene Ontology

GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0048471--C:perinuclear region of cytoplasm
GO:0005802--C:trans-Golgi network
GO:0050829--P:defense response to Gram-negative bacterium
GO:0090161--P:Golgi ribbon formation
GO:0043001--P:Golgi to plasma membrane protein transport
GO:0016236--P:macroautophagy
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0001920--P:negative regulation of receptor recycling
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:1904417--P:positive regulation of xenophagy
GO:0000042--P:protein targeting to Golgi

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002037	Ailuropoda melanoleuca	86.49	0.00e+00	831.00
IUUC-Apl-003812	Anas platyrhynchos	53.04	5.00e-137	481.00
IUUC-Aca-004625	Anolis carolinensis	51.34	1.00e-128	453.00
IUUC-Aly-005781	Arabidopsis lyrata	55.00	2.20e-02	33.50
IUUC-Ame-011116	Astyanax mexicanus	46.88	1.00e-51	197.00
IUUC-Bta-013240	Bos taurus	80.10	0.00e+00	858.00
IUUC-Cja-019911	Callithrix jacchus	78.62	0.00e+00	796.00
IUUC-Cfa-020330	Canis familiaris	85.88	0.00e+00	867.00
IUUC-Cpo-021753	Cavia porcellus	75.08	0.00e+00	766.00
IUUC-Csa-023662	Chlorocebus sabaeus	79.80	0.00e+00	801.00
IUUC-Cho-024574	Choloepus hoffmanni	68.75	9.00e-66	243.00
IUUC-Dre-027720	Danio rerio	39.65	1.00e-86	313.00
IUUC-Dno-029079	Dasypus novemcinctus	75.51	0.00e+00	742.00
IUUC-Dor-030890	Dipodomys ordii	75.89	0.00e+00	784.00
IUUC-Ete-032568	Echinops telfairi	73.15	0.00e+00	662.00
IUUC-Eca-033528	Equus caballus	83.84	0.00e+00	855.00
IUUC-Eeu-035219	Erinaceus europaeus	70.22	0.00e+00	745.00
IUUC-Fca-035852	Felis catus	85.20	0.00e+00	861.00
IUUC-Fal-036862	Ficedula albicollis	53.83	9.00e-132	463.00
IUUC-Gmo-038735	Gadus morhua	37.63	7.00e-70	258.00
IUUC-Gga-040939	Gallus gallus	51.52	5.00e-132	464.00
IUUC-Gac-041580	Gasterosteus aculeatus	41.18	1.00e-87	317.00
IUUC-Ggo-045034	Gorilla gorilla	71.26	0.00e+00	726.00
IUUC-Hsa-046624	Homo sapiens	79.29	0.00e+00	814.00
IUUC-Itr-048288	Ictidomys tridecemlineatus	70.76	0.00e+00	739.00
IUUC-Lch-049720	Latimeria chalumnae	47.04	2.00e-71	263.00
IUUC-Loc-052185	Lepisosteus oculatus	42.74	5.00e-96	345.00
IUUC-Laf-054079	Loxodonta africana	79.12	0.00e+00	793.00
IUUC-Mcc-055674	Macaca mulatta	80.78	0.00e+00	799.00
IUUC-Meu-056769	Macropus eugenii	84.62	8.00e-72	264.00
IUUC-Mga-060203	Meleagris gallopavo	51.58	2.00e-124	439.00
IUUC-Mmr-061492	Microcebus murinus	79.76	0.00e+00	790.00
IUUC-Mdo-063051	Monodelphis domestica	69.95	0.00e+00	726.00
IUUC-Mmu-063409	Mus musculus	73.85	0.00e+00	794.00
IUUC-Mlu-066957	Myotis lucifugus	78.74	0.00e+00	752.00
IUUC-Ncr-068766	Neurospora crassa	31.82	8.00e-02	32.00
IUUC-Nle-069973	Nomascus leucogenys	78.79	0.00e+00	801.00
IUUC-Opr-071049	Ochotona princeps	72.01	0.00e+00	666.00
IUUC-Ont-071915	Oreochromis niloticus	40.65	7.00e-84	304.00
IUUC-Oan-072965	Ornithorhynchus anatinus	67.34	0.00e+00	689.00
IUUC-Ocu-074029	Oryctolagus cuniculus	69.10	4.00e-177	614.00
IUUC-Ola-087019	Oryzias latipes	39.78	9.00e-81	294.00
IUUC-Oga-088613	Otolemur garnettii	78.15	0.00e+00	804.00
IUUC-Oar-090386	Ovis aries	79.76	0.00e+00	852.00
IUUC-Ptr-091619	Pan troglodytes	79.12	0.00e+00	811.00
IUUC-Pan-092178	Papio anubis	78.89	0.00e+00	786.00
IUUC-Psi-093214	Pelodiscus sinensis	58.07	2.00e-149	522.00
IUUC-Pfo-096901	Poecilia formosa	37.50	1.00e-73	270.00
IUUC-Pab-097560	Pongo abelii	72.05	0.00e+00	690.00
IUUC-Pca-100853	Procavia capensis	69.94	7.00e-116	410.00
IUUC-Pva-102255	Pteropus vampyrus	81.63	0.00e+00	790.00
IUUC-Rno-105812	Rattus norvegicus	76.74	0.00e+00	815.00
IUUC-Sha-107225	Sarcophilus harrisii	73.46	1.00e-138	486.00
IUUC-Sar-113736	Sorex araneus	66.16	3.00e-114	405.00
IUUC-Ssc-115422	Sus scrofa	81.12	0.00e+00	862.00
IUUC-Tgu-116924	Taeniopygia guttata	53.72	2.00e-130	459.00
IUUC-Tru-117695	Takifugu rubripes	38.69	9.00e-83	300.00
IUUC-Tsy-119090	Tarsius syrichta	72.29	2.00e-124	439.00
IUUC-Tni-120645	Tetraodon nigroviridis	39.75	3.00e-84	305.00
IUUC-Tbe-127970	Tupaia belangeri	65.32	3.00e-124	439.00
IUUC-Ttr-129244	Tursiops truncatus	79.49	0.00e+00	791.00
IUUC-Vpa-130313	Vicugna pacos	77.46	0.00e+00	744.00
IUUC-Xtr-132115	Xenopus tropicalis	42.65	2.00e-87	316.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence