iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ola-086988

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

BAAF04036196

Gene Name

hectd2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000003746.1	ENSORLT00000004667.1	ENSORLP00000004666.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.20e-98	330.9	350	687

Active Site

Position(s)	Description	Evidence
655	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpd.lglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlp 91
           dlkk+l+v+fvgE+gld+gG+t+e++ ll+++++++d +g+f+y ++++++++ + +      ++ + F+++G+l+g+a++++  ld++
   Q: 350  DLKKKLRVTFVGEAGLDMGGLTKEWFLLLVRQIFHTDyVGMFTYMKDSRCHWFSSWKC-----DNYSEFQLVGTLMGLAVYNSIALDIH 433
           89**********************************9679***********9976655.....789*********************** PP
   S: 92   lsksfyklllgk..............klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVt 166
           ++  +y++ll+                 +ledl++v+pel++ l e++++ e ++ee  + ltf++s+e++g +k+++LkpgG++ipVt
   Q: 434  FPLYCYRKLLSPptvpcdqnafvgmaTATLEDLQQVMPELAHGLGELLSY-EGNVEED-FYLTFQISQEEMGIMKSYNLKPGGDKIPVT 520
           *********9995555555555555559*********************9.6788885.****************************** PP
   S: 167  neNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevlee 255
           ++N++eYv+l+v++ l+++i +q++af+ Gf++v+  + l l+++ee+e+l+cG++e+d+++l+k ++y+ gy++ + +++ Fwev+ +
   Q: 521  KQNRKEYVQLYVDFLLNKSIYKQFAAFYHGFHSVCASDALMLLRPEEVEMLVCGSPELDMSALQKAAQYE-GYSKADTTVRCFWEVVLA 608
           *********************************************************************5.5***************** PP
   S: 256  fsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           f+ e +k++L+F+Tgs+r+P+gG+a+l+   f i+k d  +d+lP s+TCfn+++LP+Y + ++lk+kL++Ai++++gF+l+
   Q: 609  FTLELQKKLLHFATGSDRVPVGGMADLN---FKISKiDVPTDWLPVSHTCFNQICLPPYRTRKELKHKLTIAISNAEGFGLE 687
           ****************************...8999988899**************************************985 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

RELPPICNDV RQKHRLSIDT LPPELKAPFP LDPIIPLRTK TTKEFQEDMD RATQSGDWRE 60
VRDFYLTTFE SFIEINAAFK REANGLFNTI EDSGVNAKFV NAVYDTLLGT PQDIQKSVLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAGAACTGC CTCCAATCTG CAATGATGTT CGTCAGAAGC ACCGACTCTC CATCGACACT 60
CTGCCTCCAG AACTCAAAGC CCCGTTCCCC TTGGACCCCA TCATTCCACT TCGTACCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	76.27	0.00e+00	1127.00
IUUC-Apl-003589	Anas platyrhynchos	77.73	0.00e+00	1121.00
IUUC-Aca-004350	Anolis carolinensis	74.53	0.00e+00	1080.00
IUUC-Ago-007908	Ashbya gossypii	35.33	1.00e-82	300.00
IUUC-Acl-008288	Aspergillus clavatus	34.32	2.00e-91	330.00
IUUC-Afl-008402	Aspergillus flavus	33.77	4.00e-87	315.00
IUUC-Afu-008762	Aspergillus fumigatus	33.61	4.00e-90	326.00
IUUC-Ani-009176	Aspergillus nidulans	34.83	8.00e-91	328.00
IUUC-Ang-009791	Aspergillus niger	35.02	5.00e-90	326.00
IUUC-Aor-009921	Aspergillus oryzae	33.61	2.00e-86	313.00
IUUC-Ate-010295	Aspergillus terreus	34.99	8.00e-95	342.00
IUUC-Ame-010660	Astyanax mexicanus	81.94	2.00e-153	535.00
IUUC-Bgr-011981	Blumeria graminis	33.50	2.00e-86	314.00
IUUC-Bta-012945	Bos taurus	75.84	0.00e+00	1096.00
IUUC-Bci-013697	Botrytis cinerea	37.97	3.00e-78	287.00
IUUC-Cja-019263	Callithrix jacchus	74.96	0.00e+00	1085.00
IUUC-Cfa-020486	Canis familiaris	77.67	0.00e+00	1078.00
IUUC-Cpo-021755	Cavia porcellus	77.16	0.00e+00	1130.00
IUUC-Csa-023814	Chlorocebus sabaeus	75.77	0.00e+00	1029.00
IUUC-Cho-024980	Choloepus hoffmanni	62.01	0.00e+00	859.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	40.35	1.00e-92	334.00
IUUC-Dre-028551	Danio rerio	81.22	0.00e+00	1158.00
IUUC-Dno-029497	Dasypus novemcinctus	73.91	0.00e+00	1042.00
IUUC-Dor-030867	Dipodomys ordii	65.50	0.00e+00	914.00
IUUC-Dse-031239	Dothistroma septosporum	30.39	8.00e-87	315.00
IUUC-Ete-032902	Echinops telfairi	64.92	0.00e+00	925.00
IUUC-Eca-033678	Equus caballus	76.13	0.00e+00	1112.00
IUUC-Eeu-035262	Erinaceus europaeus	64.05	0.00e+00	887.00
IUUC-Fca-035590	Felis catus	76.71	0.00e+00	1129.00
IUUC-Fal-037123	Ficedula albicollis	74.28	0.00e+00	1060.00
IUUC-Fox-037941	Fusarium oxysporum	39.80	2.00e-97	350.00
IUUC-Fso-038388	Fusarium solani	40.79	7.00e-100	358.00
IUUC-Gmo-039553	Gadus morhua	73.83	0.00e+00	936.00
IUUC-Ggr-040110	Gaeumannomyces graminis	38.61	9.00e-93	335.00
IUUC-Gga-040406	Gallus gallus	78.46	0.00e+00	1152.00
IUUC-Gac-042141	Gasterosteus aculeatus	92.47	0.00e+00	1326.00
IUUC-Ggo-045504	Gorilla gorilla	75.25	0.00e+00	1091.00
IUUC-Hsa-045786	Homo sapiens	75.69	0.00e+00	1095.00
IUUC-Itr-048050	Ictidomys tridecemlineatus	71.26	0.00e+00	1019.00
IUUC-Kpa-049152	Komagataella pastoris	31.41	7.00e-73	268.00
IUUC-Lch-049824	Latimeria chalumnae	77.62	0.00e+00	988.00
IUUC-Loc-052173	Lepisosteus oculatus	80.49	0.00e+00	1147.00
IUUC-Laf-054017	Loxodonta africana	76.56	0.00e+00	1115.00
IUUC-Mcc-055713	Macaca mulatta	75.40	0.00e+00	1091.00
IUUC-Meu-056212	Macropus eugenii	61.54	8.00e-99	354.00
IUUC-Mor-057045	Magnaporthe oryzae	38.14	7.00e-86	312.00
IUUC-Mla-059187	Melampsora laricipopulina	40.34	6.00e-81	294.00
IUUC-Mga-059884	Meleagris gallopavo	71.41	0.00e+00	1008.00
IUUC-Mmr-061344	Microcebus murinus	75.55	0.00e+00	1118.00
IUUC-Mdo-062653	Monodelphis domestica	75.58	0.00e+00	1095.00
IUUC-Mmu-063775	Mus musculus	74.71	0.00e+00	1038.00
IUUC-Mpu-066069	Mustela putorius furo	76.32	0.00e+00	1087.00
IUUC-Mlu-067925	Myotis lucifugus	76.42	0.00e+00	1112.00
IUUC-Nfi-068439	Neosartorya fischeri	33.77	9.00e-90	325.00
IUUC-Ncr-068903	Neurospora crassa	39.43	8.00e-90	325.00
IUUC-Nle-070046	Nomascus leucogenys	75.54	0.00e+00	1112.00
IUUC-Opr-071085	Ochotona princeps	64.43	2.00e-111	396.00
IUUC-Ont-072126	Oreochromis niloticus	94.03	0.00e+00	1355.00
IUUC-Oan-072933	Ornithorhynchus anatinus	76.27	0.00e+00	1043.00
IUUC-Ocu-073800	Oryctolagus cuniculus	76.32	0.00e+00	1073.00
IUUC-Oga-088117	Otolemur garnettii	77.80	0.00e+00	951.00
IUUC-Oar-089371	Ovis aries	75.98	0.00e+00	1084.00
IUUC-Ptr-090551	Pan troglodytes	75.40	0.00e+00	1091.00
IUUC-Pan-092067	Papio anubis	75.69	0.00e+00	1096.00
IUUC-Psi-092963	Pelodiscus sinensis	76.27	0.00e+00	1075.00
IUUC-Pfo-096562	Poecilia formosa	91.85	0.00e+00	1327.00
IUUC-Pab-098680	Pongo abelii	75.69	0.00e+00	1093.00
IUUC-Pca-100986	Procavia capensis	61.06	0.00e+00	732.00
IUUC-Pva-102219	Pteropus vampyrus	68.72	0.00e+00	846.00
IUUC-Pgr-103315	Puccinia graminis	35.25	1.00e-90	327.00
IUUC-Ptt-103736	Puccinia triticina	39.28	2.00e-89	323.00
IUUC-Rno-105270	Rattus norvegicus	74.96	0.00e+00	1045.00
IUUC-Sce-106306	Saccharomyces cerevisiae	35.56	1.00e-74	274.00
IUUC-Sha-106819	Sarcophilus harrisii	76.31	0.00e+00	1120.00
IUUC-Spo-108271	Schizosaccharomyces pombe	33.39	3.00e-86	312.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	37.94	1.00e-79	291.00
IUUC-Sar-113134	Sorex araneus	68.85	0.00e+00	965.00
IUUC-Ssc-115441	Sus scrofa	76.16	0.00e+00	1097.00
IUUC-Tgu-117166	Taeniopygia guttata	75.84	0.00e+00	1067.00
IUUC-Tsy-118898	Tarsius syrichta	66.37	0.00e+00	871.00
IUUC-Tre-122108	Trichoderma reesei	37.55	1.00e-85	311.00
IUUC-Tvi-122644	Trichoderma virens	37.63	2.00e-90	327.00
IUUC-Tme-127004	Tuber melanosporum	34.87	2.00e-101	364.00
IUUC-Tbe-127292	Tupaia belangeri	62.45	0.00e+00	855.00
IUUC-Ttr-128352	Tursiops truncatus	73.51	0.00e+00	1052.00
IUUC-Vda-129969	Verticillium dahliae	39.25	7.00e-89	322.00
IUUC-Vpa-130218	Vicugna pacos	74.40	0.00e+00	769.00
IUUC-Xtr-132594	Xenopus tropicalis	72.46	0.00e+00	1015.00
IUUC-Xma-134157	Xiphophorus maculatus	91.05	0.00e+00	1238.00
IUUC-Yli-134470	Yarrowia lipolytica	32.10	6.00e-77	282.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence