iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092667

Ensembl Protein ID

ENSPANP00000019975.1

UniProt Accession

A0A096P3Q0; A0A096P3Q0_PAPAN

Genbank Protein ID

ENSPANP00000019975

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01098308

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000023104.1	ENSPANT00000021043.1	ENSPANP00000019975.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.20e-06	27.7	141	180
ULD/UDP/UFD/RAWUL	1.10e-30	106.0	254	349

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C +C   f d + +  C H f+++C+ ++        ++ +CP+C+
   Q: 141  CVLCGGYFIDATTIIECLHSFCKTCIVRY------LETSKYCPICD 180
           ********99999****************......**********5 PP

ULD/UDP/UFD/RAWUL

   S: 1    islsLeplesnkakddsk..........lkkkylrcsarltVkhlkkflaeklklsssyevdllcedevLednetLeeikyifiwkkeg 79
           isls+e++++n+ +++ +          ++k+ylrc+a++tV+hl+kfl++k+++++++++d+++e+e+L+d++tL++i+yi++w+++g
   Q: 254  ISLSIEFFDQNRLDRKVNkdkekskeevNDKRYLRCPAAMTVMHLRKFLRSKMDIPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNG 342
           7899999999998887768888899999************************************************************* PP
   S: 80   pLvLqYr 86
           pL+L+Yr
   Q: 343  PLPLKYR 349
           ******9 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MELSESVQKG FQMLADRGSF DSNAFTLLLR AAFQSLLDAQ ADEAVLDHPD LKHIDPVVLK 60
HCHAAAATYI LEAGKHRADK STLSTYLEDC KFDRERIELF CTEYQNNKNS LEILLGRIFY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCGCCCCGA GCCGCGTGCG CGCGCGGCCG CATCAGCTGA GCGCGCGGCG CGTGTCACGT 60
GGTGTGCGTG TCGAAGGTCA CGGCGCGCTC ACAATGGAGC TCTCCGAGTC TGTGCAGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032443--RAWUL
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF16207--RAWUL

SMART

SM00184--RING

Gene Ontology

GO:0000792--C:heterochromatin
GO:0016604--C:nuclear body
GO:0031519--C:PcG protein complex
GO:0000151--C:ubiquitin ligase complex
GO:1990841--F:promoter-specific chromatin binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0008270--F:zinc ion binding
GO:0007420--P:brain development
GO:0006306--P:DNA methylation
GO:0048704--P:embryonic skeletal system morphogenesis
GO:0016573--P:histone acetylation
GO:0016574--P:histone ubiquitination
GO:0006959--P:humoral immune response
GO:0001701--P:in utero embryonic development
GO:2001234--P:negative regulation of apoptotic signaling pathway
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030890--P:positive regulation of B cell proliferation
GO:0033092--P:positive regulation of immature T cell proliferation in thymus
GO:2000011--P:regulation of adaxial/abaxial pattern formation
GO:0021903--P:rostrocaudal neural tube patterning
GO:0048103--P:somatic stem cell division

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000603	Aegilops tauschii	40.85	8.00e-12	65.10
IUUC-Aml-001498	Ailuropoda melanoleuca	99.24	4.00e-158	550.00
IUUC-Apl-004208	Anas platyrhynchos	96.44	5.00e-123	433.00
IUUC-Aca-004661	Anolis carolinensis	92.02	5.00e-137	480.00
IUUC-Aly-006155	Arabidopsis lyrata	40.00	6.00e-12	65.50
IUUC-Ath-007649	Arabidopsis thaliana	42.50	2.00e-12	67.00
IUUC-Ame-010610	Astyanax mexicanus	83.79	4.00e-129	454.00
IUUC-Bta-012606	Bos taurus	99.24	2.00e-158	551.00
IUUC-Bol-015090	Brassica oleracea	36.63	3.00e-13	69.70
IUUC-Cja-019482	Callithrix jacchus	100.00	1.00e-159	555.00
IUUC-Cfa-020482	Canis familiaris	99.24	4.00e-158	550.00
IUUC-Cpo-022061	Cavia porcellus	99.62	4.00e-159	553.00
IUUC-Csa-024102	Chlorocebus sabaeus	99.48	0.00e+00	801.00
IUUC-Cho-025081	Choloepus hoffmanni	81.93	2.00e-112	398.00
IUUC-Cin-025612	Ciona intestinalis	49.30	2.00e-52	199.00
IUUC-Dre-027929	Danio rerio	86.31	4.00e-137	480.00
IUUC-Dno-029797	Dasypus novemcinctus	98.87	2.00e-157	548.00
IUUC-Dor-030256	Dipodomys ordii	95.82	2.00e-146	511.00
IUUC-Dme-031904	Drosophila melanogaster	44.74	6.00e-52	200.00
IUUC-Ete-033148	Echinops telfairi	64.71	1.00e-83	302.00
IUUC-Eca-033318	Equus caballus	99.25	4.00e-159	553.00
IUUC-Eeu-034547	Erinaceus europaeus	83.77	2.00e-128	451.00
IUUC-Fca-035866	Felis catus	99.62	2.00e-158	551.00
IUUC-Fal-036660	Ficedula albicollis	97.34	4.00e-148	517.00
IUUC-Gmo-039341	Gadus morhua	82.31	4.00e-126	444.00
IUUC-Gga-040611	Gallus gallus	96.96	8.00e-148	516.00
IUUC-Gac-041888	Gasterosteus aculeatus	82.38	8.00e-126	442.00
IUUC-Gma-042798	Glycine max	39.51	8.00e-12	64.70
IUUC-Ggo-045027	Gorilla gorilla	100.00	1.00e-159	555.00
IUUC-Hsa-045665	Homo sapiens	94.58	0.00e+00	788.00
IUUC-Itr-049045	Ictidomys tridecemlineatus	99.24	1.00e-156	545.00
IUUC-Lch-049714	Latimeria chalumnae	89.02	2.00e-143	501.00
IUUC-Loc-052161	Lepisosteus oculatus	86.43	9.00e-135	472.00
IUUC-Laf-054108	Loxodonta africana	97.75	1.00e-156	545.00
IUUC-Mcc-055562	Macaca mulatta	94.83	0.00e+00	791.00
IUUC-Meu-056709	Macropus eugenii	98.48	1.00e-157	548.00
IUUC-Mga-060104	Meleagris gallopavo	94.44	1.00e-103	369.00
IUUC-Mmr-061191	Microcebus murinus	93.10	0.00e+00	778.00
IUUC-Mdo-062711	Monodelphis domestica	93.19	3.00e-154	537.00
IUUC-Mmu-064255	Mus musculus	95.44	3.00e-146	511.00
IUUC-Mpu-066466	Mustela putorius furo	98.86	7.00e-158	549.00
IUUC-Mlu-067622	Myotis lucifugus	99.62	4.00e-159	553.00
IUUC-Nle-069253	Nomascus leucogenys	94.95	0.00e+00	773.00
IUUC-Opr-070511	Ochotona princeps	100.00	2.00e-159	555.00
IUUC-Ont-072177	Oreochromis niloticus	84.23	1.00e-129	456.00
IUUC-Oan-073336	Ornithorhynchus anatinus	98.48	2.00e-157	548.00
IUUC-Ocu-074113	Oryctolagus cuniculus	99.62	1.00e-148	518.00
IUUC-Osa-086282	Oryza sativa	42.25	6.00e-12	65.50
IUUC-Ola-087057	Oryzias latipes	85.19	6.00e-124	436.00
IUUC-Oga-088346	Otolemur garnettii	100.00	1.00e-159	555.00
IUUC-Oar-089843	Ovis aries	99.24	2.00e-158	551.00
IUUC-Ptr-090486	Pan troglodytes	100.00	1.00e-159	555.00
IUUC-Psi-093469	Pelodiscus sinensis	96.96	2.00e-155	541.00
IUUC-Pma-094481	Petromyzon marinus	74.04	3.00e-90	323.00
IUUC-Pfo-097156	Poecilia formosa	81.11	4.00e-131	460.00
IUUC-Pab-097670	Pongo abelii	100.00	1.00e-159	555.00
IUUC-Pop-098807	Populus trichocarpa	37.08	2.00e-12	67.00
IUUC-Pca-100551	Procavia capensis	70.57	8.00e-111	393.00
IUUC-Pva-102800	Pteropus vampyrus	100.00	1.00e-159	555.00
IUUC-Rno-105128	Rattus norvegicus	94.30	2.00e-149	521.00
IUUC-Sha-106747	Sarcophilus harrisii	98.48	5.00e-147	513.00
IUUC-Sar-113416	Sorex araneus	100.00	2.00e-159	554.00
IUUC-Ssc-115864	Sus scrofa	100.00	1.00e-159	555.00
IUUC-Tgu-116851	Taeniopygia guttata	96.44	1.00e-123	435.00
IUUC-Tru-117698	Takifugu rubripes	86.18	1.00e-124	439.00
IUUC-Tsy-119590	Tarsius syrichta	99.62	4.00e-159	553.00
IUUC-Tni-120170	Tetraodon nigroviridis	83.85	9.00e-129	452.00
IUUC-Tae-123760	Triticum aestivum	40.85	1.00e-11	64.70
IUUC-Tbe-127790	Tupaia belangeri	99.62	4.00e-159	553.00
IUUC-Ttr-129316	Tursiops truncatus	100.00	5.00e-159	553.00
IUUC-Vpa-130669	Vicugna pacos	100.00	5.00e-159	553.00
IUUC-Xtr-131912	Xenopus tropicalis	91.29	2.00e-134	471.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence