iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000027807.9	ENSDART00000149973.1	ENSDARP00000124324.1
ENSDARG00000027807.9	ENSDART00000032212.7	ENSDARP00000034214.7

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.50e-11	43.8	58	114

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvk...elegkrGlfPenFvekle 63
            +lydy+a +dd+L++++Gd+++ i   ++ e+W+  +      ++k+G +P+n+v+ +e
   Q: 58   VALYDYTARTDDDLSFNAGDKLEPI---TKGEDWWFSKAitgISANKKGYIPANYVAPVE 114
           69***********************...999****99778888899**********9987 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MGDVRERIIT CCQSVFQCFR DPDTSPSPDT GKRHIEVITN EFAKPQNREL PPTPVLYVAL 60
YDYTARTDDD LSFNAGDKLE PITKGEDWWF SKAITGISAN KKGYIPANYV APVESLDAEP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTCCAGTTT TACTGCCGTC AGGGGCTGTG CTGACAGCCT TATCTCGTGT CACACAAGTC 60
CAAGGGTTTT TCATTTCTTC TATCGATCAC AGTATGGATG TATAACTCTT CAGCTCATTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

KEGG

dre:567549

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003394	Anas platyrhynchos	54.35	6.00e-160	557.00
IUUC-Aca-004553	Anolis carolinensis	59.16	6.00e-178	617.00
IUUC-Cel-018682	Caenorhabditis elegans	57.05	2.00e-152	532.00
IUUC-Cja-019885	Callithrix jacchus	64.86	9.00e-180	623.00
IUUC-Cin-025605	Ciona intestinalis	56.40	6.00e-156	544.00
IUUC-Dno-029689	Dasypus novemcinctus	64.47	2.00e-174	605.00
IUUC-Dme-031976	Drosophila melanogaster	62.09	2.00e-170	592.00
IUUC-Eeu-034770	Erinaceus europaeus	54.52	3.00e-120	425.00
IUUC-Fal-036892	Ficedula albicollis	58.92	2.00e-164	572.00
IUUC-Gga-041072	Gallus gallus	57.36	1.00e-163	570.00
IUUC-Loc-052913	Lepisosteus oculatus	69.32	0.00e+00	722.00
IUUC-Mga-059456	Meleagris gallopavo	57.72	2.00e-162	565.00
IUUC-Mmr-061480	Microcebus murinus	58.78	2.00e-172	598.00
IUUC-Mlu-067167	Myotis lucifugus	58.75	2.00e-170	592.00
IUUC-Nle-069786	Nomascus leucogenys	64.86	5.00e-180	624.00
IUUC-Ont-072417	Oreochromis niloticus	71.73	0.00e+00	775.00
IUUC-Oin-079715	Oryza indica	30.50	5.00e-23	103.00
IUUC-Ola-086419	Oryzias latipes	73.82	0.00e+00	718.00
IUUC-Pan-092732	Papio anubis	64.64	8.00e-179	620.00
IUUC-Psi-093899	Pelodiscus sinensis	64.42	6.00e-178	617.00
IUUC-Pma-094230	Petromyzon marinus	58.66	9.00e-162	563.00
IUUC-Pfo-096035	Poecilia formosa	68.23	0.00e+00	687.00
IUUC-Rno-105269	Rattus norvegicus	63.36	1.00e-173	603.00
IUUC-Tgu-116491	Taeniopygia guttata	59.10	1.00e-165	575.00
IUUC-Tru-117795	Takifugu rubripes	64.47	0.00e+00	694.00
IUUC-Tni-120512	Tetraodon nigroviridis	69.71	0.00e+00	770.00
IUUC-Ttr-128817	Tursiops truncatus	64.57	3.00e-177	615.00
IUUC-Vpa-130389	Vicugna pacos	57.43	8.00e-161	560.00
IUUC-Vvi-131057	Vitis vinifera	31.27	3.00e-23	103.00
IUUC-Xtr-132360	Xenopus tropicalis	55.47	9.00e-167	580.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence