iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000010024.2	ENSCJAT00000019585.2	ENSCJAP00000018537.2
ENSCJAG00000010024.2	ENSCJAT00000019580.2	ENSCJAP00000018532.2
ENSCJAG00000010024.2	ENSCJAT00000019553.2	ENSCJAP00000018507.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.00e-17	63.8	751	802

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 8    vlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           + y++ a +  eL+l++Gdvv++ +    d+gW+kg  e++g+ G fP+ +ve+
   Q: 751  ARYNFAARDMRELSLREGDVVRIYSRIGGDQGWWKG--ETNGRIGWFPSTYVEE 802
           67**********************************..9*************86 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

FLCLKNIRTF LKVCHDKFGL RNSELFDPFD LFDVRDFGKV ISAVSRLSLH SIAQSKGIRP 60
FPSEETTEND DDVYRSLEEL ADEHDLGEDI YDCVPCEDGG DDIYEDIIKV EVQQPMVSLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCCTGTGTT TGAAGAACAT ACGGACCTTC CTTAAAGTCT GCCACGATAA ATTCGGATTA 60
AGGAACAGCG AGCTGTTCGA CCCCTTTGAC CTCTTCGACG TGCGAGACTT CGGAAAGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF00307--CH
PF00169--PH
PF00621--RhoGEF
PF00017--SH2
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00109--C1
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005886--C:plasma membrane
GO:0046872--F:metal ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0016477--P:cell migration
GO:0030032--P:lamellipodium assembly
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:0030193--P:regulation of blood coagulation
GO:0008361--P:regulation of cell size
GO:0010468--P:regulation of gene expression
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001437	Ailuropoda melanoleuca	91.48	0.00e+00	1382.00
IUUC-Apl-003262	Anas platyrhynchos	88.13	0.00e+00	1359.00
IUUC-Aca-004628	Anolis carolinensis	63.57	0.00e+00	861.00
IUUC-Ath-007352	Arabidopsis thaliana	39.22	1.00e-03	38.50
IUUC-Ame-011608	Astyanax mexicanus	75.65	0.00e+00	1218.00
IUUC-Bta-013147	Bos taurus	89.29	0.00e+00	1237.00
IUUC-Cfa-020315	Canis familiaris	87.25	0.00e+00	1169.00
IUUC-Cpo-021543	Cavia porcellus	88.49	0.00e+00	1267.00
IUUC-Cre-022802	Chlamydomonas reinhardtii	42.22	6.60e+00	27.70
IUUC-Csa-024204	Chlorocebus sabaeus	91.57	0.00e+00	1420.00
IUUC-Dre-028308	Danio rerio	78.01	0.00e+00	1259.00
IUUC-Dno-029584	Dasypus novemcinctus	83.73	0.00e+00	1073.00
IUUC-Dor-031014	Dipodomys ordii	79.17	0.00e+00	1164.00
IUUC-Eca-033448	Equus caballus	88.30	0.00e+00	1370.00
IUUC-Eeu-035182	Erinaceus europaeus	78.55	9.00e-180	624.00
IUUC-Fca-035460	Felis catus	88.31	0.00e+00	1251.00
IUUC-Fal-036684	Ficedula albicollis	87.26	0.00e+00	1367.00
IUUC-Gmo-038816	Gadus morhua	72.46	0.00e+00	1035.00
IUUC-Gga-040999	Gallus gallus	84.92	0.00e+00	1325.00
IUUC-Gac-041353	Gasterosteus aculeatus	73.42	0.00e+00	1086.00
IUUC-Ggo-044558	Gorilla gorilla	93.60	0.00e+00	1426.00
IUUC-Hsa-046208	Homo sapiens	93.72	0.00e+00	1431.00
IUUC-Itr-047931	Ictidomys tridecemlineatus	86.50	0.00e+00	1144.00
IUUC-Loc-052827	Lepisosteus oculatus	78.06	0.00e+00	1257.00
IUUC-Laf-054009	Loxodonta africana	87.05	0.00e+00	1331.00
IUUC-Mcc-055054	Macaca mulatta	93.60	0.00e+00	1428.00
IUUC-Meu-056269	Macropus eugenii	84.96	0.00e+00	748.00
IUUC-Mga-060106	Meleagris gallopavo	87.89	0.00e+00	1353.00
IUUC-Mmr-061118	Microcebus murinus	91.08	0.00e+00	1406.00
IUUC-Mdo-062380	Monodelphis domestica	85.23	0.00e+00	1226.00
IUUC-Mmu-063135	Mus musculus	91.00	0.00e+00	1421.00
IUUC-Mpu-066135	Mustela putorius furo	86.68	0.00e+00	1349.00
IUUC-Nle-069465	Nomascus leucogenys	86.30	0.00e+00	1289.00
IUUC-Ont-071945	Oreochromis niloticus	77.83	0.00e+00	1204.00
IUUC-Oan-073384	Ornithorhynchus anatinus	84.29	0.00e+00	1160.00
IUUC-Ola-087499	Oryzias latipes	72.74	0.00e+00	1007.00
IUUC-Oga-088444	Otolemur garnettii	87.52	0.00e+00	1222.00
IUUC-Oar-089576	Ovis aries	86.96	0.00e+00	1187.00
IUUC-Ptr-090507	Pan troglodytes	93.71	0.00e+00	1418.00
IUUC-Pan-092325	Papio anubis	89.77	0.00e+00	1355.00
IUUC-Psi-094021	Pelodiscus sinensis	84.78	0.00e+00	1305.00
IUUC-Pma-094372	Petromyzon marinus	51.01	0.00e+00	656.00
IUUC-Pfo-096732	Poecilia formosa	78.47	0.00e+00	1235.00
IUUC-Pab-098426	Pongo abelii	76.44	0.00e+00	1098.00
IUUC-Pca-100295	Procavia capensis	89.75	0.00e+00	1404.00
IUUC-Rno-105332	Rattus norvegicus	90.48	0.00e+00	1363.00
IUUC-Sha-106529	Sarcophilus harrisii	89.27	0.00e+00	1215.00
IUUC-Ssc-116176	Sus scrofa	89.08	0.00e+00	1363.00
IUUC-Tgu-116917	Taeniopygia guttata	88.01	0.00e+00	1356.00
IUUC-Tru-118398	Takifugu rubripes	78.45	0.00e+00	974.00
IUUC-Tni-120819	Tetraodon nigroviridis	76.19	0.00e+00	1134.00
IUUC-Xtr-132747	Xenopus tropicalis	75.83	0.00e+00	1184.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence