iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-054515

Ensembl Protein ID

ENSLAFP00000022960.1

UniProt Accession

G3U552; G3U552_LOXAF

Protein Name

Uncharacterized protein

Gene Name

BIN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000032457.1	ENSLAFT00000036588.1	ENSLAFP00000022960.1
ENSLAFG00000032457.1	ENSLAFT00000029167.1	ENSLAFP00000022108.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.10e-22	80.1	383	451

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlvi...ekeeqdegWlkgvk........elegkrGlfPenFvekl 62
           +vq++ dy+a+++deL+lk+Gdvvlvi   ++eeqdegWl+gvk        ele++rG+fPenF+e++
   Q: 383  QVQAQPDYTATDTDELQLKAGDVVLVIpfqNPEEQDEGWLMGVKesdwnqhkELEKCRGVFPENFTERV 451
           699****************************************************************98 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

QVLQKLGKAD ETKDEQFEQC VQNFNKQLTR GQWQKELAHG GSLGAVVAHP ACPRPSQCWW 60
YVWGGECWPS PSHRGGCSRC WSWAGHVLWL PRHKDVFQEA LFSLLPCLSP QSRIAKRGRK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGTCCTCC AGAAGCTGGG CAAGGCGGAT GAGACTAAGG ATGAGCAGTT TGAACAGTGT 60
GTCCAGAATT TCAACAAGCA GCTGGTGAGT GTGGGCAGCC CCGGGCCTTA GGGAACTTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR003005--Amphiphysin
IPR003023--Amphiphysin_2
IPR004148--BAR_dom
IPR001452--SH3_domain

PROSITE

PS51021--BAR
PS50002--SH3

Pfam

PF03114--BAR
PF14604--SH3_9

PRINTS

PR01251--AMPHIPHYSIN
PR01253--AMPHIPHYSIN2

SMART

SM00721--BAR
SM00326--SH3

Gene Ontology

GO:0030424--C:axon
GO:0005829--C:cytosol
GO:0060987--C:lipid tube
GO:0016020--C:membrane
GO:0005635--C:nuclear envelope
GO:0060988--P:lipid tube assembly
GO:0042692--P:muscle cell differentiation
GO:0051647--P:nucleus localization
GO:0006997--P:nucleus organization
GO:0043065--P:positive regulation of apoptotic process
GO:0048711--P:positive regulation of astrocyte differentiation
GO:0071156--P:regulation of cell cycle arrest
GO:0030100--P:regulation of endocytosis
GO:0045664--P:regulation of neuron differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cja-019916	Callithrix jacchus	58.39	6.00e-110	390.00
IUUC-Mcc-055717	Macaca mulatta	55.38	4.00e-139	488.00
IUUC-Meu-056110	Macropus eugenii	45.65	9.00e-85	306.00
IUUC-Mdo-062533	Monodelphis domestica	59.33	3.00e-125	442.00
IUUC-Nle-069141	Nomascus leucogenys	62.60	6.00e-100	358.00
IUUC-Ocu-074817	Oryctolagus cuniculus	54.77	1.00e-71	264.00
IUUC-Pab-098085	Pongo abelii	62.05	3.00e-136	478.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence