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Tag Content
iUUCD ID IUUC-Eca-033387
Ensembl Protein ID ENSECAP00000004313.1
UniProt Accession F7B6Q9; F7B6Q9_HORSE
Protein Name Tyrosine-protein kinase
Gene Name ABL2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSECAG00000005708.1 ENSECAT00000006120.1 ENSECAP00000004313.1
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 2.30e-12 46.8 94 151
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++q+++W +     ++ +G +P+n+++ ++
   Q: 94   PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNQNGEWSEV--RSKNGQGWVPSNYITPVN 151
           67899************************.*********98..788899*********997 PP
   
Organism Equus caballus
Protein Sequence
(Fasta)
MVLGTVLLPP NSYGRDQDMS FCCLCPETSE TALPTLTDHF ASCVEDGFEG DKTGGSSPEA 60
LHRPYGCDVE PQALNEAIRW SSKENLLGAT ESDPNLFVAL YDFVASGDNT LSITKGEKLR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Eca-033387|UBD,SH3|Equus caballus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTGGGCAGAA GAATGGTCCT TGGGACAGTT CTGCTTCCAC CTAATAGTTA TGGCCGAGAT 60
CAGGACATGT CGTTTTGCTG CCTATGCCCT GAGACCTCAG AAACTGCTCT ACCCACCTTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Eca-033387|UBD,SH3|Equus caballus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase
Interpro

IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3
Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1
PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE
SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc
Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0030145--F:manganese ion binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0071300--P:cellular response to retinoic acid
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0007204--P:positive regulation of cytosolic calcium ion concentration
GO:0010976--P:positive regulation of neuron projection development
GO:0051353--P:positive regulation of oxidoreductase activity
GO:0010863--P:positive regulation of phospholipase C activity
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway
KEGG ecb:100053033
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002263 Ailuropoda melanoleuca 97.57 0.00e+00 2009.00
IUUC-Apl-003389 Anas platyrhynchos 86.02 0.00e+00 1742.00
IUUC-Ame-010629 Astyanax mexicanus 58.40 0.00e+00 1069.00
IUUC-Bta-013370 Bos taurus 95.99 0.00e+00 2031.00
IUUC-Cja-018894 Callithrix jacchus 96.84 0.00e+00 1992.00
IUUC-Cfa-020398 Canis familiaris 99.53 0.00e+00 1300.00
IUUC-Cpo-022367 Cavia porcellus 95.12 0.00e+00 1529.00
IUUC-Csa-023386 Chlorocebus sabaeus 97.57 0.00e+00 1996.00
IUUC-Cho-024714 Choloepus hoffmanni 89.45 0.00e+00 1891.00
IUUC-Dre-027741 Danio rerio 67.92 0.00e+00 1369.00
IUUC-Dno-029246 Dasypus novemcinctus 96.84 0.00e+00 1983.00
IUUC-Dor-030416 Dipodomys ordii 88.44 0.00e+00 1828.00
IUUC-Ete-032899 Echinops telfairi 77.19 0.00e+00 842.00
IUUC-Eeu-035058 Erinaceus europaeus 87.02 0.00e+00 1819.00
IUUC-Fca-036578 Felis catus 90.22 0.00e+00 1801.00
IUUC-Fal-037491 Ficedula albicollis 88.67 0.00e+00 1868.00
IUUC-Gmo-038509 Gadus morhua 77.36 0.00e+00 1123.00
IUUC-Gga-040638 Gallus gallus 87.94 0.00e+00 1815.00
IUUC-Gac-042550 Gasterosteus aculeatus 68.45 0.00e+00 1329.00
IUUC-Gma-043854 Glycine max 33.50 5.00e-21 96.30
IUUC-Ggo-044487 Gorilla gorilla 96.85 0.00e+00 2042.00
IUUC-Hsa-046636 Homo sapiens 96.76 0.00e+00 2043.00
IUUC-Itr-048685 Ictidomys tridecemlineatus 96.64 0.00e+00 2018.00
IUUC-Lch-049530 Latimeria chalumnae 78.14 0.00e+00 1571.00
IUUC-Lpe-051291 Leersia perrieri 31.05 4.00e-22 100.00
IUUC-Loc-051933 Lepisosteus oculatus 70.11 0.00e+00 1436.00
IUUC-Laf-053802 Loxodonta africana 96.91 0.00e+00 2061.00
IUUC-Mcc-054836 Macaca mulatta 96.85 0.00e+00 2050.00
IUUC-Mga-059277 Meleagris gallopavo 88.48 0.00e+00 1833.00
IUUC-Mmr-061206 Microcebus murinus 95.07 0.00e+00 1953.00
IUUC-Mdo-062281 Monodelphis domestica 97.56 0.00e+00 1214.00
IUUC-Mmu-063847 Mus musculus 94.27 0.00e+00 1905.00
IUUC-Mac-065247 Musa acuminata 31.45 2.00e-22 101.00
IUUC-Mpu-066309 Mustela putorius furo 96.37 0.00e+00 1300.00
IUUC-Mlu-068070 Myotis lucifugus 96.93 0.00e+00 1992.00
IUUC-Nle-070062 Nomascus leucogenys 97.99 0.00e+00 1298.00
IUUC-Opr-070534 Ochotona princeps 91.40 0.00e+00 1054.00
IUUC-Ont-072440 Oreochromis niloticus 66.49 0.00e+00 1328.00
IUUC-Oan-073526 Ornithorhynchus anatinus 89.21 0.00e+00 1763.00
IUUC-Ocu-074051 Oryctolagus cuniculus 94.68 0.00e+00 1878.00
IUUC-Ome-081788 Oryza meridionalis 28.70 1.00e-26 114.00
IUUC-Opu-083538 Oryza punctata 34.39 6.00e-23 102.00
IUUC-Ola-086752 Oryzias latipes 95.27 0.00e+00 914.00
IUUC-Oga-088767 Otolemur garnettii 91.37 0.00e+00 1798.00
IUUC-Oar-089800 Ovis aries 97.03 0.00e+00 1994.00
IUUC-Ptr-090857 Pan troglodytes 97.99 0.00e+00 1298.00
IUUC-Pan-092279 Papio anubis 97.48 0.00e+00 1993.00
IUUC-Psi-093573 Pelodiscus sinensis 88.78 0.00e+00 1803.00
IUUC-Pfo-096543 Poecilia formosa 77.24 0.00e+00 1140.00
IUUC-Pab-097949 Pongo abelii 97.39 0.00e+00 1953.00
IUUC-Pca-100370 Procavia capensis 95.13 0.00e+00 1469.00
IUUC-Pva-103220 Pteropus vampyrus 89.41 0.00e+00 1746.00
IUUC-Rno-105924 Rattus norvegicus 92.11 0.00e+00 1860.00
IUUC-Sha-107114 Sarcophilus harrisii 84.61 0.00e+00 1427.00
IUUC-Smo-109661 Selaginella moellendorffii 28.78 6.00e-22 98.20
IUUC-Sit-110219 Setaria italica 30.30 6.00e-20 92.80
IUUC-Ssc-115968 Sus scrofa 95.72 0.00e+00 2084.00
IUUC-Tgu-117301 Taeniopygia guttata 88.23 0.00e+00 1785.00
IUUC-Tru-118410 Takifugu rubripes 67.15 0.00e+00 1362.00
IUUC-Tni-119991 Tetraodon nigroviridis 67.62 0.00e+00 1368.00
IUUC-Tca-121389 Theobroma cacao 33.85 2.00e-23 104.00
IUUC-Tae-124468 Triticum aestivum 29.13 1.00e-19 92.40
IUUC-Tbe-127362 Tupaia belangeri 91.78 0.00e+00 1846.00
IUUC-Ttr-129291 Tursiops truncatus 94.77 0.00e+00 2048.00
IUUC-Vpa-130800 Vicugna pacos 94.78 0.00e+00 1602.00
IUUC-Xtr-132965 Xenopus tropicalis 69.95 0.00e+00 1397.00
Created Date 25-Jun-2017

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