iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013193

Ensembl Protein ID

ENSBTAP00000025683.3

UniProt Accession

Q1RMR9; Q1RMR9_BOVIN

Genbank Protein ID

AAI14746.1

Protein Name

Protein kinase C and casein kinase substrate in neurons 2

Genbank Nucleotide ID

DAAA02014847

Gene Name

PACSIN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000019290.3	ENSBTAT00000025683.3	ENSBTAP00000025683.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.70e-16	60.0	430	486

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++lydye+q+ deL++k+Gd ++ i ++e ++gW+kg + ++g+ Gl P+n+ve ++
   Q: 430  RVRALYDYEGQEHDELSFKAGDELTKI-EDEDEQGWCKG-RLDSGQVGLYPANYVEAIQ 486
           799************************.9**********.59*************9885 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MSVTYDDSVG VEVSSDSFWE VGNYKRTVRR IDDGHRLCTD LMNCLHERAR IEKAYAQQLT 60
EWARRWRQLV DKGPQYGTVE KAWVAVMTEA EKVSELHLEV KASLMNEDFE KIKNWQKDAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGAGGCTGGA GCGAGGGCGG GAGCTGTGGC CGGAGCCGGA GCCGGAGCCG GAGCCGGGGC 60
TTGGAGAAGC AGTCGCGGCT GGAGCGGGGC GCGCAGAGTG CCGGGAGACG AGCGGCGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase

Interpro

IPR031160--F_BAR
IPR001060--FCH_dom
IPR028521--PACSIN2
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005901--C:caveola
GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0005768--C:endosome
GO:0070062--C:extracellular exosome
GO:0019898--C:extrinsic component of membrane
GO:0005925--C:focal adhesion
GO:0016607--C:nuclear speck
GO:0055038--C:recycling endosome membrane
GO:0016301--F:kinase activity
GO:0070300--F:phosphatidic acid binding
GO:0030036--P:actin cytoskeleton organization
GO:0070836--P:caveola assembly
GO:0072584--P:caveolin-mediated endocytosis
GO:0048858--P:cell projection morphogenesis
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0036010--P:protein localization to endosome
GO:0030100--P:regulation of endocytosis

KEGG

bta:540107

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001887	Ailuropoda melanoleuca	93.00	0.00e+00	868.00
IUUC-Apl-003574	Anas platyrhynchos	86.04	0.00e+00	771.00
IUUC-Aca-004251	Anolis carolinensis	80.82	0.00e+00	748.00
IUUC-Ame-011756	Astyanax mexicanus	65.50	0.00e+00	676.00
IUUC-Cel-018168	Caenorhabditis elegans	29.72	2.00e-60	226.00
IUUC-Cja-018756	Callithrix jacchus	91.36	0.00e+00	822.00
IUUC-Cfa-020545	Canis familiaris	93.83	0.00e+00	903.00
IUUC-Cpo-022000	Cavia porcellus	88.48	0.00e+00	900.00
IUUC-Csa-024030	Chlorocebus sabaeus	89.44	0.00e+00	726.00
IUUC-Cin-025707	Ciona intestinalis	42.36	1.00e-105	376.00
IUUC-Csv-026244	Ciona savignyi	42.22	6.00e-55	206.00
IUUC-Dre-028104	Danio rerio	62.80	5.00e-165	573.00
IUUC-Dno-029429	Dasypus novemcinctus	91.85	0.00e+00	799.00
IUUC-Dor-030122	Dipodomys ordii	83.95	0.00e+00	761.00
IUUC-Dme-032120	Drosophila melanogaster	42.37	6.00e-106	377.00
IUUC-Eca-033367	Equus caballus	90.53	0.00e+00	841.00
IUUC-Eeu-034821	Erinaceus europaeus	75.10	0.00e+00	676.00
IUUC-Fca-036079	Felis catus	92.95	0.00e+00	860.00
IUUC-Fal-036682	Ficedula albicollis	85.96	0.00e+00	773.00
IUUC-Gmo-039681	Gadus morhua	64.83	5.00e-157	547.00
IUUC-Gga-040717	Gallus gallus	85.96	0.00e+00	771.00
IUUC-Gac-042262	Gasterosteus aculeatus	63.19	2.00e-171	595.00
IUUC-Ggo-044841	Gorilla gorilla	90.53	0.00e+00	789.00
IUUC-Hsa-046411	Homo sapiens	90.12	0.00e+00	785.00
IUUC-Itr-049063	Ictidomys tridecemlineatus	91.15	0.00e+00	812.00
IUUC-Loc-051975	Lepisosteus oculatus	68.97	0.00e+00	681.00
IUUC-Laf-053839	Loxodonta africana	88.52	0.00e+00	827.00
IUUC-Mcc-055783	Macaca mulatta	90.33	0.00e+00	785.00
IUUC-Mga-060087	Meleagris gallopavo	80.00	0.00e+00	696.00
IUUC-Mmr-060827	Microcebus murinus	91.98	0.00e+00	852.00
IUUC-Mmu-064109	Mus musculus	91.15	0.00e+00	848.00
IUUC-Mpu-066591	Mustela putorius furo	93.62	0.00e+00	873.00
IUUC-Mlu-067826	Myotis lucifugus	93.62	0.00e+00	872.00
IUUC-Nle-069797	Nomascus leucogenys	90.33	0.00e+00	787.00
IUUC-Oan-073076	Ornithorhynchus anatinus	83.19	1.00e-156	545.00
IUUC-Ocu-074425	Oryctolagus cuniculus	91.36	0.00e+00	820.00
IUUC-Ola-087556	Oryzias latipes	64.26	1.00e-164	573.00
IUUC-Oga-089009	Otolemur garnettii	83.86	0.00e+00	777.00
IUUC-Oar-089806	Ovis aries	99.38	0.00e+00	891.00
IUUC-Ptr-091111	Pan troglodytes	89.92	0.00e+00	783.00
IUUC-Pan-091749	Papio anubis	87.55	0.00e+00	771.00
IUUC-Psi-093704	Pelodiscus sinensis	85.53	0.00e+00	785.00
IUUC-Pfo-096680	Poecilia formosa	63.51	6.00e-169	587.00
IUUC-Pva-102649	Pteropus vampyrus	91.98	0.00e+00	831.00
IUUC-Rno-105431	Rattus norvegicus	90.98	0.00e+00	877.00
IUUC-Sha-106641	Sarcophilus harrisii	88.41	0.00e+00	810.00
IUUC-Sar-113461	Sorex araneus	81.48	0.00e+00	738.00
IUUC-Ssc-115349	Sus scrofa	94.23	0.00e+00	848.00
IUUC-Tgu-116876	Taeniopygia guttata	86.17	0.00e+00	773.00
IUUC-Tru-118306	Takifugu rubripes	66.60	2.00e-176	611.00
IUUC-Tsy-118901	Tarsius syrichta	80.90	2.00e-150	525.00
IUUC-Tni-120120	Tetraodon nigroviridis	66.53	8.00e-178	616.00
IUUC-Xtr-132925	Xenopus tropicalis	80.29	0.00e+00	753.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence