iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067543

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02046750

Gene Name

ATXN3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000011651.2	ENSMLUT00000011651.2	ENSMLUP00000010614.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
DUB/Josephin	89.55	5.00e-152	534.00	IUUC-Mmu-063600
UBD/Alpha-Helix/UIM	89.55	5.00e-152	534.00	IUUC-Mmu-063600

Active Site

Position(s)	Description	Evidence
12	N/A	{ECO:0000256\|PROSITE-ProRule:PRU00331}
117		{ECO:0000256\|PROSITE-ProRule:PRU00331}
132		{ECO:0000256\|PROSITE-ProRule:PRU00331}

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

IKFLFKQEGS LCAQHCLNNL LQGEYFSPVE LSSIAHQLDE EERMRMAEGG VTSEDYRTFL 60
QQPSGNMDDS GFFSIQVISN ALKVWGLELI LFNSPEYQRL RIDPINERSF ICNYKEHWFT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTAAATTCC TCTTTAAGGA AAGACCCTGA ACAAATCTGT TTATCAAGCC ACATTTGAAT 60
TTTTTCTTTT GGATATTAGC AAGAAGGCTC ACTTTGTGCT CAGCATTGCT TGAATAATCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR033865--Ataxin-3
IPR006155--Josephin
IPR009068--S15_NS1_RNA-bd
IPR003903--UIM_dom

PROSITE

PS50957--JOSEPHIN
PS50330--UIM

Pfam

PF02099--Josephin
PF02809--UIM

SMART

SM01246--Josephin
SM00726--UIM

Gene Ontology

GO:0005759--C:mitochondrial matrix
GO:0031966--C:mitochondrial membrane
GO:0042405--C:nuclear inclusion body
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0034605--P:cellular response to heat
GO:0071218--P:cellular response to misfolded protein
GO:0035640--P:exploration behavior
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0010810--P:regulation of cell-substrate adhesion

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002015	Ailuropoda melanoleuca	94.70	8.00e-160	556.00
IUUC-Atr-002735	Amborella trichopoda	51.16	5.00e-05	38.50
IUUC-Apl-003210	Anas platyrhynchos	80.68	1.00e-132	465.00
IUUC-Aca-005171	Anolis carolinensis	77.74	5.00e-115	407.00
IUUC-Aly-005625	Arabidopsis lyrata	44.79	5.00e-39	154.00
IUUC-Ath-007088	Arabidopsis thaliana	44.79	4.00e-39	154.00
IUUC-Ame-010715	Astyanax mexicanus	70.65	2.00e-119	422.00
IUUC-Bta-013538	Bos taurus	91.81	5.00e-159	553.00
IUUC-Bci-013745	Botrytis cinerea	34.67	8.00e-03	35.80
IUUC-Bdi-015000	Brachypodium distachyon	42.07	5.00e-34	138.00
IUUC-Bol-015894	Brassica oleracea	44.17	2.00e-39	156.00
IUUC-Bra-018020	Brassica rapa	44.44	1.00e-39	157.00
IUUC-Cel-018121	Caenorhabditis elegans	36.63	1.00e-43	169.00
IUUC-Cja-018840	Callithrix jacchus	78.78	1.00e-167	582.00
IUUC-Cfa-021035	Canis familiaris	93.75	1.00e-159	555.00
IUUC-Cpo-021776	Cavia porcellus	76.33	3.00e-160	557.00
IUUC-Csa-023257	Chlorocebus sabaeus	73.38	7.00e-123	433.00
IUUC-Cho-024878	Choloepus hoffmanni	93.26	6.00e-156	543.00
IUUC-Cgl-026754	Colletotrichum gloeosporioides	50.00	1.30e+00	28.90
IUUC-Cme-027158	Cyanidioschyzon merolae	35.25	1.00e-11	63.20
IUUC-Dre-027506	Danio rerio	67.47	2.00e-89	321.00
IUUC-Dno-029172	Dasypus novemcinctus	94.39	9.00e-159	552.00
IUUC-Dor-030900	Dipodomys ordii	93.23	1.00e-138	485.00
IUUC-Ete-033000	Echinops telfairi	66.15	7.00e-84	303.00
IUUC-Eca-034338	Equus caballus	95.76	4.00e-162	563.00
IUUC-Eeu-034585	Erinaceus europaeus	98.10	7.00e-57	213.00
IUUC-Fca-035441	Felis catus	85.11	1.00e-67	248.00
IUUC-Fal-037525	Ficedula albicollis	83.58	3.00e-124	437.00
IUUC-Gmo-039718	Gadus morhua	69.44	4.00e-109	387.00
IUUC-Gga-040774	Gallus gallus	80.60	1.00e-135	476.00
IUUC-Gac-041671	Gasterosteus aculeatus	72.54	3.00e-104	371.00
IUUC-Gma-042801	Glycine max	41.36	1.00e-35	143.00
IUUC-Ggo-044759	Gorilla gorilla	94.32	1.00e-127	449.00
IUUC-Hsa-046591	Homo sapiens	95.05	1.00e-159	555.00
IUUC-Hvu-047492	Hordeum vulgare	43.29	1.00e-32	133.00
IUUC-Itr-048851	Ictidomys tridecemlineatus	64.27	2.00e-121	428.00
IUUC-Lch-049519	Latimeria chalumnae	75.00	3.00e-109	387.00
IUUC-Lpe-050819	Leersia perrieri	43.37	5.00e-34	137.00
IUUC-Loc-051816	Lepisosteus oculatus	74.25	9.00e-126	442.00
IUUC-Laf-053784	Loxodonta africana	90.69	9.00e-157	546.00
IUUC-Mcc-055283	Macaca mulatta	94.76	2.00e-161	561.00
IUUC-Meu-056589	Macropus eugenii	85.17	2.00e-141	495.00
IUUC-Mtr-058233	Medicago truncatula	35.56	3.00e-36	145.00
IUUC-Mla-059013	Melampsora laricipopulina	39.04	1.00e-29	123.00
IUUC-Mga-059301	Meleagris gallopavo	79.33	2.00e-137	482.00
IUUC-Mmr-061038	Microcebus murinus	94.43	6.00e-161	560.00
IUUC-Mdo-062927	Monodelphis domestica	87.33	5.00e-145	506.00
IUUC-Mmu-063600	Mus musculus	89.55	3.00e-147	514.00
IUUC-Mpu-065897	Mustela putorius furo	78.31	9.00e-157	546.00
IUUC-Nle-069847	Nomascus leucogenys	86.76	3.00e-145	508.00
IUUC-Opr-070550	Ochotona princeps	83.39	1.00e-136	479.00
IUUC-Ont-071723	Oreochromis niloticus	69.38	2.00e-108	385.00
IUUC-Oan-073569	Ornithorhynchus anatinus	86.29	2.00e-146	511.00
IUUC-Ocu-074632	Oryctolagus cuniculus	92.63	1.00e-156	545.00
IUUC-Oba-075288	Oryza barthii	43.37	3.00e-36	145.00
IUUC-Obr-076050	Oryza brachyantha	42.77	4.00e-32	132.00
IUUC-Ogl-077174	Oryza glaberrima	43.37	3.00e-36	145.00
IUUC-Ogu-078006	Oryza glumaepatula	43.37	3.00e-36	145.00
IUUC-Oin-079278	Oryza indica	40.91	9.00e-34	137.00
IUUC-Olo-080941	Oryza longistaminata	43.37	3.00e-36	145.00
IUUC-Ome-081172	Oryza meridionalis	43.37	3.00e-36	145.00
IUUC-Oni-082239	Oryza nivara	43.37	3.00e-36	145.00
IUUC-Opu-083939	Oryza punctata	42.77	1.00e-35	143.00
IUUC-Oru-084393	Oryza rufipogon	43.37	3.00e-36	145.00
IUUC-Osa-086080	Oryza sativa	43.37	3.00e-36	145.00
IUUC-Ola-087566	Oryzias latipes	72.98	1.00e-108	385.00
IUUC-Oga-088617	Otolemur garnettii	63.59	1.00e-125	442.00
IUUC-Oar-090052	Ovis aries	92.10	2.00e-159	554.00
IUUC-Ptr-091435	Pan troglodytes	94.77	5.00e-162	563.00
IUUC-Pan-092742	Papio anubis	73.01	2.00e-121	429.00
IUUC-Psi-093313	Pelodiscus sinensis	88.03	2.00e-126	444.00
IUUC-Pma-094374	Petromyzon marinus	62.26	2.00e-85	308.00
IUUC-Pno-095003	Phaeosphaeria nodorum	33.33	2.70e-01	31.20
IUUC-Ppa-095601	Physcomitrella patens	44.79	8.00e-43	167.00
IUUC-Pfo-097327	Poecilia formosa	70.65	9.00e-109	386.00
IUUC-Pab-098611	Pongo abelii	93.28	3.00e-131	461.00
IUUC-Pca-101022	Procavia capensis	99.11	2.00e-65	242.00
IUUC-Ppe-101545	Prunus persica	43.56	5.00e-37	148.00
IUUC-Pva-102844	Pteropus vampyrus	94.08	2.00e-159	555.00
IUUC-Rno-104896	Rattus norvegicus	89.62	1.00e-151	529.00
IUUC-Sha-107106	Sarcophilus harrisii	88.40	5.00e-151	526.00
IUUC-Sit-110477	Setaria italica	43.98	2.00e-35	142.00
IUUC-Sly-111416	Solanum lycopersicum	39.13	4.00e-18	84.30
IUUC-Stu-112227	Solanum tuberosum	32.58	3.00e-21	94.70
IUUC-Sar-113534	Sorex araneus	90.43	1.00e-144	506.00
IUUC-Sbi-114751	Sorghum bicolor	34.63	6.00e-34	137.00
IUUC-Ssc-115274	Sus scrofa	94.43	4.00e-161	560.00
IUUC-Tgu-117426	Taeniopygia guttata	83.97	1.00e-135	476.00
IUUC-Tru-118059	Takifugu rubripes	74.64	2.00e-106	378.00
IUUC-Tsy-119448	Tarsius syrichta	81.82	1.00e-83	303.00
IUUC-Tni-120681	Tetraodon nigroviridis	89.34	7.00e-58	215.00
IUUC-Tca-121442	Theobroma cacao	37.02	1.00e-39	156.00
IUUC-Tae-123969	Triticum aestivum	42.17	9.00e-31	127.00
IUUC-Tbe-127638	Tupaia belangeri	87.99	1.00e-143	502.00
IUUC-Ttr-129288	Tursiops truncatus	83.62	1.00e-136	479.00
IUUC-Uma-129359	Ustilago maydis	37.85	5.00e-32	132.00
IUUC-Vpa-130788	Vicugna pacos	95.05	2.00e-160	557.00
IUUC-Vvi-131227	Vitis vinifera	42.59	2.00e-34	139.00
IUUC-Xtr-132147	Xenopus tropicalis	76.24	2.00e-122	432.00
IUUC-Xma-133144	Xiphophorus maculatus	70.34	9.00e-106	376.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence