iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088935

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03001468

Gene Name

TRIM68

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000013943.2	ENSOGAT00000013946.2	ENSOGAP00000012481.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.40e-09	37.1	16	61
E3 activity/RING/U-box	1.30e-07	31.6	10	81

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkw..pglknssskefrCPlCr 46
           C+iC++ ++d p++ +CgH f++ Cl   w  pg +  ++ + +CPlCr
   Q: 16   CPICMTFLRD-PVSIDCGHSFCHGCLsRLWevPGES--QNWAYTCPLCR 61
           ********99.***************6556666666..88899*****8 PP

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggk......tcPvtrqplteedlvPnltlrrliqa 67
           v ee +CpI ++  rdPv + +G+++   ++ +  +  g+      tcP++r+p+++ +l Pn  l ++i++
   Q: 10   VVEEVVCPICMTFLRDPVSIDCGHSFCHGCLSRLWEVPGEsqnwayTCPLCRAPVQPMNLRPNWQLANIIEK 81
           68999***************************9664444447789*********************999987 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MDPAALVEAV VEEVVCPICM TFLRDPVSID CGHSFCHGCL SRLWEVPGES QNWAYTCPLC 60
RAPVQPMNLR PNWQLANIIE KVRLLRLHPG MGLKGDVCER HEEQLKVFCK EDGLVMCEAC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATCCTG CAGCATTGGT GGAAGCTGTT GTGGAAGAAG TAGTCTGTCC CATCTGCATG 60
ACCTTCCTGA GAGACCCTGT GAGCATCGAC TGTGGCCACA GCTTCTGCCA CGGCTGTCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005730--C:nucleolus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0051865--P:protein autoubiquitination
GO:0060765--P:regulation of androgen receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002078	Ailuropoda melanoleuca	87.01	0.00e+00	799.00
IUUC-Bta-012800	Bos taurus	81.98	0.00e+00	806.00
IUUC-Cja-019382	Callithrix jacchus	84.12	0.00e+00	767.00
IUUC-Cfa-020686	Canis familiaris	83.92	1.00e-170	592.00
IUUC-Csa-023952	Chlorocebus sabaeus	84.95	0.00e+00	764.00
IUUC-Cho-024811	Choloepus hoffmanni	78.76	0.00e+00	693.00
IUUC-Dre-028631	Danio rerio	30.54	7.00e-58	218.00
IUUC-Dno-029361	Dasypus novemcinctus	83.92	0.00e+00	776.00
IUUC-Dor-030703	Dipodomys ordii	78.97	0.00e+00	708.00
IUUC-Ete-033159	Echinops telfairi	87.50	2.00e-110	392.00
IUUC-Eca-033633	Equus caballus	78.23	0.00e+00	678.00
IUUC-Eeu-034686	Erinaceus europaeus	78.10	0.00e+00	715.00
IUUC-Fca-035750	Felis catus	84.97	0.00e+00	790.00
IUUC-Ggo-045524	Gorilla gorilla	84.33	0.00e+00	764.00
IUUC-Hsa-046031	Homo sapiens	84.12	0.00e+00	790.00
IUUC-Itr-048898	Ictidomys tridecemlineatus	80.85	0.00e+00	719.00
IUUC-Laf-054264	Loxodonta africana	85.09	0.00e+00	827.00
IUUC-Mcc-055388	Macaca mulatta	84.95	0.00e+00	764.00
IUUC-Mmr-060612	Microcebus murinus	83.92	0.00e+00	775.00
IUUC-Mmu-063761	Mus musculus	74.38	0.00e+00	712.00
IUUC-Mpu-066319	Mustela putorius furo	88.45	0.00e+00	811.00
IUUC-Mlu-067368	Myotis lucifugus	85.36	0.00e+00	780.00
IUUC-Nle-069702	Nomascus leucogenys	84.33	0.00e+00	764.00
IUUC-Opr-070810	Ochotona princeps	72.23	2.00e-180	625.00
IUUC-Ont-072259	Oreochromis niloticus	33.46	1.00e-71	263.00
IUUC-Oar-089940	Ovis aries	87.42	0.00e+00	806.00
IUUC-Ptr-091056	Pan troglodytes	84.33	0.00e+00	763.00
IUUC-Pan-092165	Papio anubis	85.15	0.00e+00	761.00
IUUC-Pfo-096858	Poecilia formosa	34.24	1.00e-70	260.00
IUUC-Pab-098415	Pongo abelii	84.97	8.00e-152	529.00
IUUC-Pca-100470	Procavia capensis	78.60	0.00e+00	760.00
IUUC-Pva-102603	Pteropus vampyrus	82.47	0.00e+00	734.00
IUUC-Rno-105709	Rattus norvegicus	72.49	0.00e+00	672.00
IUUC-Sar-113101	Sorex araneus	79.59	8.00e-152	529.00
IUUC-Ssc-115920	Sus scrofa	84.74	0.00e+00	779.00
IUUC-Tbe-127512	Tupaia belangeri	75.50	1.00e-161	562.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence