iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059486

UUCD1 version

UUC-MeG-00067

Ensembl Protein ID

ENSMGAP00000000813.2

UniProt Accession

G1MRJ4; G1MRJ4_MELGA

Protein Name

Uncharacterized protein

Gene Name

KLHL12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000001374.2	ENSMGAT00000001459.2	ENSMGAP00000000813.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/BCR/BTB_3-box	95.30	0.00e+00	1018.00	IUUC-Hsa-046742
E3 adaptor/Cullin RING/BCR/BTB_3-box	89.82	0.00e+00	962.00	IUUC-Ots-000038

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

LCLFSDLQLS EKDKPYVDIQ GLTASTMEIL LDFVYTETVH VTVENVQELL PAACLLQLKG 60
VKQACCEFLE SQLDPSNCLG IRDFAETHNC VDLMQAAEVF SQKHFPEVVQ HEEFILLNQE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCTGTCTCT TCTCCGATTT ACAGCTCTCA GAGAAAGACA AACCCTACGT GGACATCCAG 60
GGGCTGACGG CTTCCACCAT GGAAATCCTG CTGGATTTTG TGTACACAGA AACCGTTCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0030134--C:ER to Golgi transport vesicle
GO:0000139--C:Golgi membrane
GO:0005815--C:microtubule organizing center
GO:0048208--P:COPII vesicle coating
GO:0006513--P:protein monoubiquitination
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002301	Ailuropoda melanoleuca	92.98	0.00e+00	984.00
IUUC-Apl-003339	Anas platyrhynchos	96.28	0.00e+00	1012.00
IUUC-Aca-004418	Anolis carolinensis	95.50	0.00e+00	1006.00
IUUC-Aly-005957	Arabidopsis lyrata	33.10	3.00e-39	155.00
IUUC-Ath-007066	Arabidopsis thaliana	33.33	1.00e-39	157.00
IUUC-Ame-011906	Astyanax mexicanus	74.20	0.00e+00	755.00
IUUC-Bta-012979	Bos taurus	91.59	0.00e+00	972.00
IUUC-Cja-019582	Callithrix jacchus	93.15	0.00e+00	986.00
IUUC-Cfa-020716	Canis familiaris	93.54	0.00e+00	991.00
IUUC-Cpo-022013	Cavia porcellus	93.74	0.00e+00	993.00
IUUC-Cre-022752	Chlamydomonas reinhardtii	28.18	9.00e-15	76.30
IUUC-Csa-023424	Chlorocebus sabaeus	93.40	0.00e+00	910.00
IUUC-Cho-024586	Choloepus hoffmanni	84.04	0.00e+00	768.00
IUUC-Dre-028344	Danio rerio	84.77	2.00e-130	457.00
IUUC-Dno-028854	Dasypus novemcinctus	93.54	0.00e+00	991.00
IUUC-Dor-030403	Dipodomys ordii	93.35	0.00e+00	988.00
IUUC-Ete-032963	Echinops telfairi	92.84	0.00e+00	962.00
IUUC-Eca-033282	Equus caballus	93.35	0.00e+00	991.00
IUUC-Eeu-034933	Erinaceus europaeus	92.16	2.00e-138	485.00
IUUC-Fca-035487	Felis catus	93.54	0.00e+00	991.00
IUUC-Fal-037059	Ficedula albicollis	96.28	0.00e+00	1008.00
IUUC-Gmo-039564	Gadus morhua	87.87	0.00e+00	953.00
IUUC-Gga-040629	Gallus gallus	96.67	0.00e+00	1017.00
IUUC-Gac-042526	Gasterosteus aculeatus	87.67	0.00e+00	949.00
IUUC-Ggo-044839	Gorilla gorilla	93.54	0.00e+00	991.00
IUUC-Hsa-046742	Homo sapiens	93.54	0.00e+00	991.00
IUUC-Itr-048958	Ictidomys tridecemlineatus	93.35	0.00e+00	988.00
IUUC-Lch-049540	Latimeria chalumnae	91.59	0.00e+00	985.00
IUUC-Loc-051923	Lepisosteus oculatus	90.41	0.00e+00	966.00
IUUC-Laf-054370	Loxodonta africana	93.35	0.00e+00	990.00
IUUC-Mcc-054852	Macaca mulatta	93.54	0.00e+00	991.00
IUUC-Mmr-061777	Microcebus murinus	93.54	0.00e+00	990.00
IUUC-Mdo-061990	Monodelphis domestica	93.15	0.00e+00	988.00
IUUC-Mmu-064053	Mus musculus	92.95	0.00e+00	988.00
IUUC-Mac-064654	Musa acuminata	34.02	3.00e-40	159.00
IUUC-Mpu-066623	Mustela putorius furo	79.72	0.00e+00	668.00
IUUC-Mlu-067648	Myotis lucifugus	94.52	0.00e+00	1010.00
IUUC-Nle-069714	Nomascus leucogenys	93.54	0.00e+00	991.00
IUUC-Opr-071143	Ochotona princeps	86.30	0.00e+00	894.00
IUUC-Ont-071848	Oreochromis niloticus	88.65	0.00e+00	959.00
IUUC-Ocu-074379	Oryctolagus cuniculus	93.35	0.00e+00	990.00
IUUC-Ola-087469	Oryzias latipes	88.26	0.00e+00	957.00
IUUC-Oar-090144	Ovis aries	93.15	0.00e+00	987.00
IUUC-Ptr-091406	Pan troglodytes	93.54	0.00e+00	991.00
IUUC-Pan-092762	Papio anubis	92.38	0.00e+00	971.00
IUUC-Psi-093391	Pelodiscus sinensis	95.50	0.00e+00	1007.00
IUUC-Pma-094134	Petromyzon marinus	72.23	0.00e+00	746.00
IUUC-Pfo-096404	Poecilia formosa	88.65	0.00e+00	958.00
IUUC-Pab-098425	Pongo abelii	93.15	0.00e+00	987.00
IUUC-Pca-101093	Procavia capensis	93.75	9.00e-143	499.00
IUUC-Pva-102239	Pteropus vampyrus	83.92	0.00e+00	875.00
IUUC-Rno-104921	Rattus norvegicus	93.15	0.00e+00	990.00
IUUC-Sha-106625	Sarcophilus harrisii	94.13	0.00e+00	994.00
IUUC-Sar-113468	Sorex araneus	81.45	1.00e-164	572.00
IUUC-Ssc-116106	Sus scrofa	93.15	0.00e+00	987.00
IUUC-Tgu-117402	Taeniopygia guttata	71.40	0.00e+00	669.00
IUUC-Tru-117546	Takifugu rubripes	87.87	0.00e+00	954.00
IUUC-Tsy-118802	Tarsius syrichta	89.86	0.00e+00	928.00
IUUC-Tni-119999	Tetraodon nigroviridis	88.26	0.00e+00	957.00
IUUC-Tca-121074	Theobroma cacao	31.43	6.00e-38	152.00
IUUC-Tbe-127987	Tupaia belangeri	94.59	0.00e+00	811.00
IUUC-Ttr-128613	Tursiops truncatus	85.49	0.00e+00	886.00
IUUC-Vvi-131673	Vitis vinifera	32.99	3.00e-40	159.00
IUUC-Xtr-132401	Xenopus tropicalis	89.84	2.00e-139	487.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence