iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-089057

Ensembl Protein ID

ENSOGAP00000021788.1

UniProt Accession

H0Y095; H0Y095_OTOGA

Genbank Protein ID

ENSOGAP00000021788

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03056464

Gene Name

SOCS6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000034731.1	ENSOGAT00000031893.1	ENSOGAP00000021788.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	3.50e-17	62.0	488	535

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
            ++ +++ ++rSLq+LCR++Ir++++++ +   +kLPLP+++kdYL++++y
   Q: 488  TNPVSRFMQVRSLQYLCRFVIRQYTRIDLI---QKLPLPNKMKDYLQEKHY 535
           5788999********************888...***************997 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MKKISLKTFR KSFNLNKSKE ETDFMVVQQA SLAGDFGKDD SLFGSCYSKD MASCDLNSED 60
EKGGKARSKS ESLMGTLKRR LSAKQKPKGK AGAPPGSSAD EDAFSSSSAP LVFKDVRAQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGAAAA TTAGTCTTAA AACTTTCCGG AAATCTTTTA ACCTGAATAA AAGTAAAGAA 60
GAAACTGATT TCATGGTAGT ACAACAAGCA TCCCTAGCCG GTGACTTCGG GAAGGATGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028421--SOCS6
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0001772--C:immunological synapse
GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0050868--P:negative regulation of T cell activation
GO:0010498--P:proteasomal protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0040008--P:regulation of growth

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001911	Ailuropoda melanoleuca	91.78	0.00e+00	916.00
IUUC-Atr-002940	Amborella trichopoda	27.27	3.80e-01	28.90
IUUC-Apl-004035	Anas platyrhynchos	87.85	0.00e+00	868.00
IUUC-Aca-004782	Anolis carolinensis	86.19	0.00e+00	838.00
IUUC-Ame-011790	Astyanax mexicanus	68.13	0.00e+00	636.00
IUUC-Bta-012579	Bos taurus	95.17	2.00e-108	385.00
IUUC-Bol-015843	Brassica oleracea	28.77	3.20e-02	33.10
IUUC-Cel-018643	Caenorhabditis elegans	33.59	1.00e-11	62.80
IUUC-Cja-019528	Callithrix jacchus	94.02	0.00e+00	983.00
IUUC-Cfa-020678	Canis familiaris	91.78	0.00e+00	936.00
IUUC-Cpo-021947	Cavia porcellus	91.40	0.00e+00	966.00
IUUC-Csa-023935	Chlorocebus sabaeus	93.64	0.00e+00	959.00
IUUC-Cho-024477	Choloepus hoffmanni	90.65	0.00e+00	950.00
IUUC-Cin-025413	Ciona intestinalis	68.24	3.00e-66	245.00
IUUC-Csv-026247	Ciona savignyi	67.47	4.00e-65	241.00
IUUC-Cne-026906	Cryptococcus neoformans	26.04	7.60e-02	32.30
IUUC-Dre-027636	Danio rerio	68.52	0.00e+00	631.00
IUUC-Dno-029048	Dasypus novemcinctus	90.65	0.00e+00	927.00
IUUC-Dor-030401	Dipodomys ordii	88.81	0.00e+00	894.00
IUUC-Ete-033116	Echinops telfairi	48.76	5.00e-57	214.00
IUUC-Eca-033825	Equus caballus	91.96	0.00e+00	902.00
IUUC-Fca-036253	Felis catus	90.47	0.00e+00	849.00
IUUC-Fal-037614	Ficedula albicollis	87.66	0.00e+00	867.00
IUUC-Fox-037898	Fusarium oxysporum	26.25	6.20e-02	31.20
IUUC-Gmo-038928	Gadus morhua	68.45	0.00e+00	659.00
IUUC-Gga-040177	Gallus gallus	87.85	0.00e+00	864.00
IUUC-Gac-042263	Gasterosteus aculeatus	70.09	0.00e+00	691.00
IUUC-Ggo-045288	Gorilla gorilla	92.71	0.00e+00	952.00
IUUC-Hsa-046409	Homo sapiens	93.08	0.00e+00	953.00
IUUC-Itr-048996	Ictidomys tridecemlineatus	91.40	0.00e+00	900.00
IUUC-Lch-050354	Latimeria chalumnae	81.16	0.00e+00	845.00
IUUC-Loc-052319	Lepisosteus oculatus	81.34	0.00e+00	815.00
IUUC-Laf-054070	Loxodonta africana	89.91	0.00e+00	888.00
IUUC-Mcc-055045	Macaca mulatta	93.83	0.00e+00	963.00
IUUC-Meu-055917	Macropus eugenii	87.85	0.00e+00	930.00
IUUC-Mga-059273	Meleagris gallopavo	87.85	0.00e+00	862.00
IUUC-Mmr-061597	Microcebus murinus	94.39	0.00e+00	971.00
IUUC-Mdo-062492	Monodelphis domestica	62.97	1.00e-107	382.00
IUUC-Mmu-063374	Mus musculus	83.09	0.00e+00	827.00
IUUC-Mpu-065967	Mustela putorius furo	88.60	0.00e+00	884.00
IUUC-Mlu-067532	Myotis lucifugus	90.84	0.00e+00	910.00
IUUC-Nle-069373	Nomascus leucogenys	93.27	0.00e+00	954.00
IUUC-Opr-070873	Ochotona princeps	88.79	0.00e+00	937.00
IUUC-Ont-072498	Oreochromis niloticus	70.30	0.00e+00	721.00
IUUC-Oan-072943	Ornithorhynchus anatinus	73.06	2.00e-99	355.00
IUUC-Ocu-073870	Oryctolagus cuniculus	92.90	0.00e+00	952.00
IUUC-Ola-086866	Oryzias latipes	89.40	6.00e-105	373.00
IUUC-Oar-089841	Ovis aries	61.38	2.00e-165	575.00
IUUC-Ptr-091054	Pan troglodytes	93.08	0.00e+00	951.00
IUUC-Pma-094253	Petromyzon marinus	82.11	3.00e-92	332.00
IUUC-Pfo-097179	Poecilia formosa	64.70	2.00e-174	605.00
IUUC-Pab-097702	Pongo abelii	93.46	0.00e+00	957.00
IUUC-Pca-100671	Procavia capensis	85.96	6.00e-130	457.00
IUUC-Rno-106044	Rattus norvegicus	81.16	0.00e+00	823.00
IUUC-Sha-107139	Sarcophilus harrisii	87.35	0.00e+00	850.00
IUUC-Smo-108823	Selaginella moellendorffii	33.96	3.70e-02	32.00
IUUC-Sly-111748	Solanum lycopersicum	46.15	2.60e-01	30.00
IUUC-Ssc-115343	Sus scrofa	91.96	0.00e+00	942.00
IUUC-Tgu-117061	Taeniopygia guttata	87.66	0.00e+00	867.00
IUUC-Tni-119829	Tetraodon nigroviridis	67.47	0.00e+00	649.00
IUUC-Ttr-129148	Tursiops truncatus	91.59	0.00e+00	886.00
IUUC-Vpa-130780	Vicugna pacos	90.28	0.00e+00	862.00
IUUC-Vvi-130966	Vitis vinifera	32.69	6.90e-02	30.80
IUUC-Xtr-132513	Xenopus tropicalis	80.75	0.00e+00	832.00
IUUC-Xma-133904	Xiphophorus maculatus	68.58	0.00e+00	664.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence