iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.40e-30	102.8	4	54

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            +ly+++a+++deL ++kGd+++++ + + d++W k+  el+g +G++P+n+++
   Q: 4    VALYNFQATESDELAFNKGDTLKIL-NMDDDQNWYKA--ELRGAEGFVPKNYIR 54
           58***********************.999******99..9************97 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MESVALYNFQ ATESDELAFN KGDTLKILNM DDDQNWYKAE LRGAEGFVPK NYIRVKPHPW 60
YSGRISRQLA EETLMKRNHL GAFLIRESES SPGEFSVSVN YGDQVQHFKV LREASGKYFL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCAACTGCA GGAAGCAGGA AGCTGTAGCT GCTGGGTCCT CGGCTGAAGC CCAGGGGCAG 60
TGGGATGGAG TCCGTGGCCC TCTACAACTT CCAGGCCACC GAGAGTGATG AGCTGGCCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

KEGG

rno:363616

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001277	Ailuropoda melanoleuca	89.40	3.00e-116	410.00
IUUC-Apl-003499	Anas platyrhynchos	61.64	4.00e-73	267.00
IUUC-Aca-004922	Anolis carolinensis	66.36	7.00e-87	313.00
IUUC-Bta-012909	Bos taurus	88.48	2.00e-115	407.00
IUUC-Cja-018796	Callithrix jacchus	88.94	6.00e-116	409.00
IUUC-Cfa-021023	Canis familiaris	89.40	3.00e-117	414.00
IUUC-Cpo-021502	Cavia porcellus	90.78	2.00e-117	414.00
IUUC-Csa-024099	Chlorocebus sabaeus	89.86	4.00e-116	409.00
IUUC-Dno-029057	Dasypus novemcinctus	85.63	2.00e-83	300.00
IUUC-Eca-033722	Equus caballus	76.28	9.00e-98	348.00
IUUC-Eeu-035125	Erinaceus europaeus	77.78	1.00e-44	171.00
IUUC-Fca-036087	Felis catus	89.86	1.00e-116	411.00
IUUC-Fal-037633	Ficedula albicollis	75.35	1.00e-96	345.00
IUUC-Gga-041204	Gallus gallus	74.42	3.00e-96	343.00
IUUC-Ggo-044579	Gorilla gorilla	90.78	5.00e-118	416.00
IUUC-Hsa-045927	Homo sapiens	90.78	5.00e-118	416.00
IUUC-Loc-052457	Lepisosteus oculatus	59.26	7.00e-75	273.00
IUUC-Laf-053794	Loxodonta africana	88.94	3.00e-117	413.00
IUUC-Mcc-055527	Macaca mulatta	90.32	5.00e-117	413.00
IUUC-Meu-056608	Macropus eugenii	79.06	2.00e-84	304.00
IUUC-Mmr-060743	Microcebus murinus	80.65	6.00e-102	362.00
IUUC-Mdo-063025	Monodelphis domestica	81.57	1.00e-108	385.00
IUUC-Mmu-064395	Mus musculus	97.70	2.00e-126	444.00
IUUC-Mpu-066088	Mustela putorius furo	88.48	2.00e-114	405.00
IUUC-Mlu-067003	Myotis lucifugus	88.48	3.00e-115	407.00
IUUC-Opr-071051	Ochotona princeps	66.82	8.00e-78	282.00
IUUC-Ont-071576	Oreochromis niloticus	59.72	2.00e-77	281.00
IUUC-Oan-073107	Ornithorhynchus anatinus	64.19	3.00e-79	287.00
IUUC-Ocu-074963	Oryctolagus cuniculus	88.07	2.00e-103	368.00
IUUC-Ola-086725	Oryzias latipes	55.86	6.00e-70	256.00
IUUC-Oga-088158	Otolemur garnettii	88.48	4.00e-116	410.00
IUUC-Oar-090223	Ovis aries	85.71	9.00e-111	392.00
IUUC-Pan-092422	Papio anubis	90.78	9.00e-118	415.00
IUUC-Psi-093655	Pelodiscus sinensis	74.66	3.00e-98	350.00
IUUC-Pfo-096278	Poecilia formosa	58.33	1.00e-73	268.00
IUUC-Pca-100573	Procavia capensis	86.19	5.00e-94	336.00
IUUC-Pva-102471	Pteropus vampyrus	88.48	3.00e-101	360.00
IUUC-Sha-107209	Sarcophilus harrisii	80.18	7.00e-98	349.00
IUUC-Tru-118065	Takifugu rubripes	56.94	7.00e-72	263.00
IUUC-Tni-120563	Tetraodon nigroviridis	55.56	3.00e-68	250.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence