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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Hsa-045793
UUCD1 version UUC-HoS-00888
Ensembl Protein ID ENSP00000230122.3
UniProt Accession O43167; Q17RC6; Q5TED5; Q8N455; ZBT24_HUMAN
Genbank Protein ID BAA23713.2; CAI23346.1; AAH36731.1; AAI17375.1; AAI17377.1
Protein Name Zinc finger and BTB domain-containing protein 24; Zinc finger protein 450
Genbank Nucleotide ID AB007901; AL109947; BC036731; BC117374; BC117376
Gene Name ZBTB24; KIAA0441; ZNF450
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000112365.4 ENST00000230122.3 ENSP00000230122.3
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmiRTarBasemicroRNATRANSFAC
TargetScanRepTarSomamiRmiRcode
RAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Disease-associated Variation
ClinVarGWASdbOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB 3.50e-13 51.4 37 100
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_Other: BTB
   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkld 66
           +D++l+v++++f+ahk+ LaasS++F+ +f  e e +  ++ + ++++ ++ f  ll+F+Ytg l 
   Q: 37   CDITLIVENVHFRAHKALLAASSEYFSMMFAEEGEIG--QSIYMLEGMVADTFGILLEFIYTGYLH 100
           8*****************************7766665..57777888****************886 PP
   
Organism Homo sapiens
Functional Description
(View)

Functional Description


     May be involved in BMP2-induced transcription.
 May be involved in BMP2-induced transcription.
Protein Sequence
(Fasta)
MAETSPEPSG QLVVHSDAHS DTVLASFEDQ RKKGFLCDIT LIVENVHFRA HKALLAASSE 60
YFSMMFAEEG EIGQSIYMLE GMVADTFGIL LEFIYTGYLH ASEKSTEQIL ATAQFLKVYD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-045793|E3,BTB_Other|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGCGCTTCCG GGTTGGCTGT GGCTGTGGCT GCGGCGGCGG CGCAGGAGCA GAAACCGGTG 60
CGGCGCAGAA GCCCCAGAGG CGGGCGGGGC GGAGCGGAGG GCCAGCGGGC CCCGGCGTGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-045793|E3,BTB_Other|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0225--Disease mutation
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR000210--BTB/POZ_dom
IPR023413--GFP-like
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2
Pfam

PF00651--BTB
SMART

SM00225--BTB
SM00355--ZnF_C2H2
Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0046872--F:metal ion binding
GO:0002244--P:hematopoietic progenitor cell differentiation
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
KEGG hsa:9841
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001722 Ailuropoda melanoleuca 85.93 0.00e+00 1118.00
IUUC-Apl-003854 Anas platyrhynchos 73.98 0.00e+00 913.00
IUUC-Ame-011090 Astyanax mexicanus 50.30 2.00e-168 586.00
IUUC-Bta-013015 Bos taurus 89.90 0.00e+00 1196.00
IUUC-Cja-019537 Callithrix jacchus 96.56 0.00e+00 1273.00
IUUC-Cfa-021048 Canis familiaris 87.72 0.00e+00 1146.00
IUUC-Cpo-021818 Cavia porcellus 89.02 0.00e+00 1114.00
IUUC-Csa-023709 Chlorocebus sabaeus 97.43 0.00e+00 1293.00
IUUC-Cho-024967 Choloepus hoffmanni 82.09 0.00e+00 984.00
IUUC-Dre-028277 Danio rerio 46.61 1.00e-152 533.00
IUUC-Dno-029444 Dasypus novemcinctus 89.81 0.00e+00 1206.00
IUUC-Dor-030792 Dipodomys ordii 91.12 0.00e+00 1229.00
IUUC-Ete-032398 Echinops telfairi 80.46 0.00e+00 999.00
IUUC-Eca-034254 Equus caballus 91.69 0.00e+00 1201.00
IUUC-Fca-035831 Felis catus 87.83 0.00e+00 1098.00
IUUC-Fal-037055 Ficedula albicollis 71.16 0.00e+00 832.00
IUUC-Gmo-039469 Gadus morhua 46.37 2.00e-144 506.00
IUUC-Gga-040581 Gallus gallus 72.07 0.00e+00 906.00
IUUC-Gac-041537 Gasterosteus aculeatus 49.85 2.00e-154 538.00
IUUC-Ggo-045494 Gorilla gorilla 99.00 0.00e+00 1273.00
IUUC-Itr-048173 Ictidomys tridecemlineatus 92.39 0.00e+00 1159.00
IUUC-Lch-050497 Latimeria chalumnae 55.30 2.00e-132 466.00
IUUC-Loc-052654 Lepisosteus oculatus 59.08 7.00e-160 557.00
IUUC-Laf-053350 Loxodonta africana 89.60 0.00e+00 1123.00
IUUC-Mcc-055866 Macaca mulatta 98.28 0.00e+00 1267.00
IUUC-Meu-056118 Macropus eugenii 73.83 4.00e-123 435.00
IUUC-Mga-060047 Meleagris gallopavo 71.05 0.00e+00 886.00
IUUC-Mmr-060588 Microcebus murinus 89.67 0.00e+00 1141.00
IUUC-Mdo-062336 Monodelphis domestica 80.61 0.00e+00 993.00
IUUC-Mmu-063926 Mus musculus 85.06 0.00e+00 1121.00
IUUC-Mpu-066822 Mustela putorius furo 86.49 0.00e+00 1063.00
IUUC-Mlu-067720 Myotis lucifugus 90.17 0.00e+00 1149.00
IUUC-Nle-070056 Nomascus leucogenys 99.00 0.00e+00 1277.00
IUUC-Opr-070424 Ochotona princeps 78.22 0.00e+00 990.00
IUUC-Ont-072021 Oreochromis niloticus 47.80 6.00e-172 597.00
IUUC-Oan-073359 Ornithorhynchus anatinus 76.24 2.00e-88 320.00
IUUC-Ocu-074138 Oryctolagus cuniculus 87.07 0.00e+00 1119.00
IUUC-Oga-088106 Otolemur garnettii 91.87 0.00e+00 1182.00
IUUC-Oar-089235 Ovis aries 93.03 0.00e+00 1278.00
IUUC-Ptr-090645 Pan troglodytes 99.70 0.00e+00 1263.00
IUUC-Pan-092161 Papio anubis 97.44 0.00e+00 1253.00
IUUC-Psi-093172 Pelodiscus sinensis 74.74 0.00e+00 916.00
IUUC-Pfo-096250 Poecilia formosa 55.33 6.00e-129 454.00
IUUC-Pab-098359 Pongo abelii 98.71 0.00e+00 1271.00
IUUC-Pva-103156 Pteropus vampyrus 92.12 0.00e+00 1264.00
IUUC-Rno-105441 Rattus norvegicus 86.13 0.00e+00 1148.00
IUUC-Sha-107110 Sarcophilus harrisii 76.69 0.00e+00 966.00
IUUC-Sar-113684 Sorex araneus 87.70 0.00e+00 1166.00
IUUC-Ssc-115999 Sus scrofa 91.40 0.00e+00 1252.00
IUUC-Tgu-116975 Taeniopygia guttata 70.86 0.00e+00 835.00
IUUC-Tru-117553 Takifugu rubripes 46.51 1.00e-159 556.00
IUUC-Tsy-119107 Tarsius syrichta 92.61 0.00e+00 644.00
IUUC-Tni-120348 Tetraodon nigroviridis 46.46 1.00e-141 497.00
IUUC-Tbe-127729 Tupaia belangeri 89.26 0.00e+00 1199.00
IUUC-Ttr-129257 Tursiops truncatus 92.55 0.00e+00 1226.00
IUUC-Vpa-130203 Vicugna pacos 91.73 0.00e+00 1171.00
IUUC-Xtr-131980 Xenopus tropicalis 45.52 7.00e-121 427.00
Created Date 25-Jun-2017

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