iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010629

Ensembl Protein ID

ENSAMXP00000002359.1

UniProt Accession

W5K448; W5K448_ASTMX

Genbank Protein ID

ENSAMXP00000002359

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

APWO01044193

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000002300.1	ENSAMXT00000002359.1	ENSAMXP00000002359.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.30e-12	46.9	70	127

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++q+++W +     ++ +G +P+n+++ ++
   Q: 70   PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNQNGEWSEV--RSKNGQGWVPSNYITPVN 127
           67899************************.*********98..788899*********997 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MPLRTLLSSS SFEEDRSRLS GPRGPGFRDV ARCYLPEALH RPFGLDSAAL TEAVRWSSKE 60
NLLGAAESDP NLFVALYDFV ASGDNTLSIT KGEKLRVLGY NQNGEWSEVR SKNGQGWVPS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGACTTTCTC GCTTTCACAC TTTCTCTACA GAAGCTAGGG TGATGGTTAT TGGAGGCAGC 60
TGCCTCCACA AACATTTCCC CTGTGTGTGT GTGTGTATCA GCATGTGTGT GTGTGTGTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS50001--SH2
PS50002--SH3

Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN

SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002263	Ailuropoda melanoleuca	57.60	0.00e+00	1063.00
IUUC-Apl-003389	Anas platyrhynchos	57.79	0.00e+00	1024.00
IUUC-Bta-013370	Bos taurus	56.97	0.00e+00	1055.00
IUUC-Cja-018894	Callithrix jacchus	58.11	0.00e+00	1070.00
IUUC-Cpo-022367	Cavia porcellus	57.57	0.00e+00	1036.00
IUUC-Csa-023386	Chlorocebus sabaeus	57.74	0.00e+00	1073.00
IUUC-Dre-027741	Danio rerio	70.61	0.00e+00	1293.00
IUUC-Dno-029246	Dasypus novemcinctus	56.97	0.00e+00	1045.00
IUUC-Ete-032899	Echinops telfairi	94.72	1.00e-129	457.00
IUUC-Eca-033387	Equus caballus	60.58	0.00e+00	942.00
IUUC-Eeu-035058	Erinaceus europaeus	53.45	0.00e+00	971.00
IUUC-Fal-037491	Ficedula albicollis	58.98	0.00e+00	1090.00
IUUC-Gga-040638	Gallus gallus	58.61	0.00e+00	1058.00
IUUC-Gac-042550	Gasterosteus aculeatus	64.36	0.00e+00	1165.00
IUUC-Ggo-044487	Gorilla gorilla	57.79	0.00e+00	1072.00
IUUC-Hsa-046636	Homo sapiens	57.88	0.00e+00	1073.00
IUUC-Itr-048685	Ictidomys tridecemlineatus	57.93	0.00e+00	1073.00
IUUC-Lch-049530	Latimeria chalumnae	59.79	0.00e+00	1067.00
IUUC-Loc-051933	Lepisosteus oculatus	65.93	0.00e+00	1262.00
IUUC-Laf-053802	Loxodonta africana	60.19	0.00e+00	973.00
IUUC-Mcc-054836	Macaca mulatta	58.08	0.00e+00	1072.00
IUUC-Meu-056057	Macropus eugenii	87.91	5.00e-149	522.00
IUUC-Mga-059277	Meleagris gallopavo	59.05	0.00e+00	1070.00
IUUC-Mmr-061206	Microcebus murinus	57.48	0.00e+00	1030.00
IUUC-Mmu-063847	Mus musculus	57.98	0.00e+00	1046.00
IUUC-Mlu-068070	Myotis lucifugus	57.23	0.00e+00	1056.00
IUUC-Ont-072440	Oreochromis niloticus	64.92	0.00e+00	1141.00
IUUC-Oan-073526	Ornithorhynchus anatinus	57.24	0.00e+00	1037.00
IUUC-Ocu-074051	Oryctolagus cuniculus	60.11	0.00e+00	917.00
IUUC-Oga-088767	Otolemur garnettii	55.45	0.00e+00	998.00
IUUC-Oar-089800	Ovis aries	56.97	0.00e+00	1055.00
IUUC-Pan-092279	Papio anubis	57.75	0.00e+00	1071.00
IUUC-Psi-093573	Pelodiscus sinensis	59.00	0.00e+00	1018.00
IUUC-Pfo-096543	Poecilia formosa	63.00	0.00e+00	1127.00
IUUC-Pab-097949	Pongo abelii	57.49	0.00e+00	1046.00
IUUC-Pca-100370	Procavia capensis	49.05	2.00e-177	616.00
IUUC-Rno-105924	Rattus norvegicus	57.47	0.00e+00	1041.00
IUUC-Ssc-115968	Sus scrofa	57.99	0.00e+00	1061.00
IUUC-Tgu-117301	Taeniopygia guttata	58.96	0.00e+00	1070.00
IUUC-Tru-118410	Takifugu rubripes	65.83	0.00e+00	1222.00
IUUC-Tni-119991	Tetraodon nigroviridis	64.24	0.00e+00	1207.00
IUUC-Ttr-129291	Tursiops truncatus	58.08	0.00e+00	1071.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence