iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049530

Ensembl Protein ID

ENSLACP00000006377.1

UniProt Accession

H3A9Q6; H3A9Q6_LATCH

Genbank Protein ID

ENSLACP00000006377

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AFYH01157619

Gene Name

ABL2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000005659.1	ENSLACT00000006430.1	ENSLACP00000006377.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.40e-12	46.8	92	149

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++q+++W +     ++ +G +P+n+++ ++
   Q: 92   PNVFVALYDFVASGDNTLSITKGEKLRVL-GYNQNGEWSEV--RSKNGQGWVPSNYITPVN 149
           67899************************.*********98..788899*********997 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MGQQVGRVGE GAGPQQRGSR ASSSGAARPA GRRRETAGIG GTGRAGEAGF NIFAQHEALH 60
RPFGCDAESQ ALNEAVRWSS KENLLGATES DPNVFVALYD FVASGDNTLS ITKGEKLRVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCTCTGCT CTGTCAATTT TGTCTATGGT AAAAATGGCA GTAGTTGCTG CAGGAGCGCG 60
GAGCGGCCGA ACGGTGACCG AGCGTCAGTG AGCTTCAGGG GGGACGGGGA AGCCCCGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE

SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

KEGG

lcm:102352150

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002263	Ailuropoda melanoleuca	78.53	0.00e+00	1607.00
IUUC-Apl-003389	Anas platyrhynchos	77.05	0.00e+00	1541.00
IUUC-Ame-010629	Astyanax mexicanus	60.09	0.00e+00	1076.00
IUUC-Bta-013370	Bos taurus	75.64	0.00e+00	1613.00
IUUC-Cja-018894	Callithrix jacchus	77.05	0.00e+00	1615.00
IUUC-Cfa-020398	Canis familiaris	91.22	0.00e+00	1152.00
IUUC-Cpo-022367	Cavia porcellus	75.58	0.00e+00	1540.00
IUUC-Csa-023386	Chlorocebus sabaeus	78.44	0.00e+00	1611.00
IUUC-Cho-024714	Choloepus hoffmanni	86.82	0.00e+00	1281.00
IUUC-Dre-027741	Danio rerio	66.59	0.00e+00	1423.00
IUUC-Dno-029246	Dasypus novemcinctus	77.30	0.00e+00	1600.00
IUUC-Dor-030416	Dipodomys ordii	70.42	0.00e+00	1457.00
IUUC-Ete-032899	Echinops telfairi	54.91	9.00e-165	574.00
IUUC-Eca-033387	Equus caballus	83.06	0.00e+00	1445.00
IUUC-Eeu-035058	Erinaceus europaeus	68.72	0.00e+00	1505.00
IUUC-Fca-036578	Felis catus	72.49	0.00e+00	1425.00
IUUC-Fal-037491	Ficedula albicollis	78.85	0.00e+00	1645.00
IUUC-Gmo-038509	Gadus morhua	70.58	0.00e+00	1168.00
IUUC-Gga-040638	Gallus gallus	78.94	0.00e+00	1630.00
IUUC-Gac-042550	Gasterosteus aculeatus	68.93	0.00e+00	1353.00
IUUC-Ggo-044487	Gorilla gorilla	75.66	0.00e+00	1626.00
IUUC-Hsa-046636	Homo sapiens	75.58	0.00e+00	1625.00
IUUC-Itr-048685	Ictidomys tridecemlineatus	78.77	0.00e+00	1598.00
IUUC-Loc-051933	Lepisosteus oculatus	72.67	0.00e+00	1513.00
IUUC-Laf-053802	Loxodonta africana	75.75	0.00e+00	1677.00
IUUC-Mcc-054836	Macaca mulatta	75.91	0.00e+00	1639.00
IUUC-Mga-059277	Meleagris gallopavo	79.61	0.00e+00	1627.00
IUUC-Mmr-061206	Microcebus murinus	75.88	0.00e+00	1566.00
IUUC-Mdo-062281	Monodelphis domestica	88.08	0.00e+00	1181.00
IUUC-Mmu-063847	Mus musculus	74.55	0.00e+00	1570.00
IUUC-Mac-065247	Musa acuminata	31.45	1.00e-22	101.00
IUUC-Mpu-066309	Mustela putorius furo	86.04	0.00e+00	1200.00
IUUC-Mlu-068070	Myotis lucifugus	78.71	0.00e+00	1597.00
IUUC-Nle-070062	Nomascus leucogenys	84.97	0.00e+00	1172.00
IUUC-Opr-070534	Ochotona princeps	76.55	0.00e+00	858.00
IUUC-Ont-072440	Oreochromis niloticus	70.44	0.00e+00	1278.00
IUUC-Oan-073526	Ornithorhynchus anatinus	83.73	0.00e+00	1445.00
IUUC-Ocu-074051	Oryctolagus cuniculus	78.92	0.00e+00	1576.00
IUUC-Oba-075747	Oryza barthii	33.67	1.00e-21	99.40
IUUC-Obr-076676	Oryza brachyantha	33.67	1.00e-22	101.00
IUUC-Opu-083538	Oryza punctata	34.39	3.00e-23	103.00
IUUC-Oga-088767	Otolemur garnettii	72.53	0.00e+00	1404.00
IUUC-Oar-089800	Ovis aries	78.41	0.00e+00	1582.00
IUUC-Ptr-090857	Pan troglodytes	84.68	0.00e+00	1169.00
IUUC-Pan-092279	Papio anubis	77.01	0.00e+00	1637.00
IUUC-Psi-093573	Pelodiscus sinensis	79.34	0.00e+00	1602.00
IUUC-Pfo-096543	Poecilia formosa	65.11	0.00e+00	1303.00
IUUC-Pab-097949	Pongo abelii	76.84	0.00e+00	1597.00
IUUC-Pca-100370	Procavia capensis	74.32	0.00e+00	1132.00
IUUC-Pva-103220	Pteropus vampyrus	72.06	0.00e+00	1261.00
IUUC-Rno-105924	Rattus norvegicus	74.34	0.00e+00	1572.00
IUUC-Sha-107114	Sarcophilus harrisii	84.62	0.00e+00	1268.00
IUUC-Sit-110219	Setaria italica	30.30	3.00e-20	94.00
IUUC-Ssc-115968	Sus scrofa	75.31	0.00e+00	1632.00
IUUC-Tgu-117301	Taeniopygia guttata	79.02	0.00e+00	1600.00
IUUC-Tru-118410	Takifugu rubripes	66.59	0.00e+00	1400.00
IUUC-Tni-119991	Tetraodon nigroviridis	66.48	0.00e+00	1402.00
IUUC-Tca-121389	Theobroma cacao	34.36	2.00e-24	107.00
IUUC-Tur-126824	Triticum urartu	32.16	7.00e-20	92.40
IUUC-Tbe-127362	Tupaia belangeri	76.56	0.00e+00	1389.00
IUUC-Ttr-129291	Tursiops truncatus	78.39	0.00e+00	1596.00
IUUC-Vpa-130800	Vicugna pacos	85.22	0.00e+00	1348.00
IUUC-Vvi-131057	Vitis vinifera	30.85	9.00e-23	102.00
IUUC-Xtr-132965	Xenopus tropicalis	70.12	0.00e+00	1243.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence