iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011903

Ensembl Protein ID

ENSAMXP00000009431.1

UniProt Accession

W5KPB9; W5KPB9_ASTMX

Genbank Protein ID

ENSAMXP00000009431

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

APWO01101327

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000009178.1	ENSAMXT00000009431.1	ENSAMXP00000009431.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.00e-14	53.0	79	136

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++++++W+++  ++++ +G +P+n+++ ++
   Q: 79   PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNHNGEWCEA--QTKNGQGWVPSNYITPVN 136
           68899************************.***********..79999**********997 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MGQQPGKSVG DQRRPSLPAL NFIKGGGKRD SSRHGAHNCN VFTVHEALQR PDFDSPGLSE 60
AARWNSKENL LAGPSENDPN LFVALYDFVA SGDNTLSITK GEKLRVLGYN HNGEWCEAQT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGCAGC AGCCAGGGAA GTCTGTTGGG GACCAAAGGA GACCAAGTCT GCCTGCTCTG 60
AACTTCATCA AGGGTGGCGG GAAGCGGGAC TCATCAAGGC ATGGCGCTCA CAACTGCAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR033221--ABL1
IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE

SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001550	Ailuropoda melanoleuca	77.00	0.00e+00	1174.00
IUUC-Apl-003452	Anas platyrhynchos	68.79	0.00e+00	1310.00
IUUC-Aca-005312	Anolis carolinensis	75.16	0.00e+00	1093.00
IUUC-Bta-012351	Bos taurus	68.04	0.00e+00	1291.00
IUUC-Cja-019491	Callithrix jacchus	68.64	0.00e+00	1373.00
IUUC-Cfa-021256	Canis familiaris	68.87	0.00e+00	1373.00
IUUC-Cpo-022046	Cavia porcellus	77.44	0.00e+00	1206.00
IUUC-Csa-023046	Chlorocebus sabaeus	67.98	0.00e+00	1325.00
IUUC-Cho-024714	Choloepus hoffmanni	79.23	0.00e+00	904.00
IUUC-Dre-028190	Danio rerio	79.95	0.00e+00	1512.00
IUUC-Dno-029853	Dasypus novemcinctus	69.10	0.00e+00	1369.00
IUUC-Dor-030635	Dipodomys ordii	70.12	0.00e+00	1059.00
IUUC-Dme-032098	Drosophila melanogaster	74.47	0.00e+00	772.00
IUUC-Eca-033720	Equus caballus	68.21	0.00e+00	1291.00
IUUC-Eeu-035173	Erinaceus europaeus	73.47	0.00e+00	1130.00
IUUC-Fca-035967	Felis catus	76.39	0.00e+00	1190.00
IUUC-Fal-036723	Ficedula albicollis	68.67	0.00e+00	1310.00
IUUC-Gmo-039550	Gadus morhua	83.60	0.00e+00	1243.00
IUUC-Gga-040481	Gallus gallus	68.31	0.00e+00	1284.00
IUUC-Gac-041643	Gasterosteus aculeatus	76.40	0.00e+00	1477.00
IUUC-Gma-043854	Glycine max	29.71	4.00e-21	96.70
IUUC-Ggo-045299	Gorilla gorilla	68.04	0.00e+00	1393.00
IUUC-Hsa-047033	Homo sapiens	91.89	3.00e-36	142.00
IUUC-Itr-047935	Ictidomys tridecemlineatus	68.60	0.00e+00	1291.00
IUUC-Lch-050530	Latimeria chalumnae	73.56	0.00e+00	1208.00
IUUC-Loc-052430	Lepisosteus oculatus	85.20	0.00e+00	1040.00
IUUC-Laf-053609	Loxodonta africana	68.84	0.00e+00	1351.00
IUUC-Mcc-055654	Macaca mulatta	69.38	0.00e+00	1404.00
IUUC-Meu-056488	Macropus eugenii	67.06	0.00e+00	996.00
IUUC-Mga-059270	Meleagris gallopavo	68.74	0.00e+00	1301.00
IUUC-Mmr-060593	Microcebus murinus	75.85	0.00e+00	1122.00
IUUC-Mdo-062227	Monodelphis domestica	78.80	0.00e+00	1129.00
IUUC-Mmu-064002	Mus musculus	69.40	0.00e+00	1388.00
IUUC-Mac-065247	Musa acuminata	30.43	3.00e-23	103.00
IUUC-Mpu-066197	Mustela putorius furo	76.12	0.00e+00	1189.00
IUUC-Mlu-067255	Myotis lucifugus	68.90	0.00e+00	1291.00
IUUC-Nle-069977	Nomascus leucogenys	62.29	0.00e+00	1197.00
IUUC-Opr-070327	Ochotona princeps	69.73	0.00e+00	996.00
IUUC-Ont-072307	Oreochromis niloticus	74.65	0.00e+00	1468.00
IUUC-Oan-073100	Ornithorhynchus anatinus	76.80	0.00e+00	1157.00
IUUC-Ocu-074892	Oryctolagus cuniculus	74.00	0.00e+00	1036.00
IUUC-Opu-083538	Oryza punctata	33.00	4.00e-23	103.00
IUUC-Ola-087389	Oryzias latipes	76.50	0.00e+00	1226.00
IUUC-Oga-088145	Otolemur garnettii	69.79	0.00e+00	1295.00
IUUC-Oar-090432	Ovis aries	75.82	0.00e+00	1110.00
IUUC-Ptr-090800	Pan troglodytes	68.36	0.00e+00	1397.00
IUUC-Psi-093078	Pelodiscus sinensis	69.97	0.00e+00	1346.00
IUUC-Pma-094420	Petromyzon marinus	77.16	0.00e+00	891.00
IUUC-Pfo-096979	Poecilia formosa	78.00	0.00e+00	1202.00
IUUC-Pca-100874	Procavia capensis	95.00	0.00e+00	734.00
IUUC-Pva-102415	Pteropus vampyrus	76.41	0.00e+00	1197.00
IUUC-Rno-105682	Rattus norvegicus	69.57	0.00e+00	1396.00
IUUC-Sha-106711	Sarcophilus harrisii	76.11	0.00e+00	1141.00
IUUC-Sit-110444	Setaria italica	31.66	4.00e-19	90.10
IUUC-Sbi-114480	Sorghum bicolor	31.66	1.00e-23	105.00
IUUC-Ssc-115472	Sus scrofa	76.47	0.00e+00	1199.00
IUUC-Tgu-117037	Taeniopygia guttata	69.02	0.00e+00	1384.00
IUUC-Tru-118324	Takifugu rubripes	66.64	0.00e+00	1317.00
IUUC-Tsy-119216	Tarsius syrichta	91.74	0.00e+00	1068.00
IUUC-Tni-119950	Tetraodon nigroviridis	66.86	0.00e+00	1266.00
IUUC-Tca-121389	Theobroma cacao	32.82	5.00e-23	103.00
IUUC-Tae-122912	Triticum aestivum	28.70	4.00e-19	90.10
IUUC-Tbe-127362	Tupaia belangeri	63.92	0.00e+00	894.00
IUUC-Ttr-128209	Tursiops truncatus	73.90	0.00e+00	1210.00
IUUC-Vpa-130800	Vicugna pacos	66.98	0.00e+00	902.00
IUUC-Xtr-132477	Xenopus tropicalis	69.36	0.00e+00	984.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence