iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-004035

Ensembl Protein ID

ENSAPLP00000001252.1

UniProt Accession

R0LMQ6; R0LMQ6_ANAPL

Genbank Protein ID

EOB06989.1

Protein Name

Suppressor of cytokine signaling 6

Genbank Nucleotide ID

ADON01021129

Gene Name

SOCS6; Anapl_15043

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000001830.1	ENSAPLT00000001823.1	ENSAPLP00000001252.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	2.60e-17	62.2	487	534

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
            ++ +++ ++rSLq+LCR++Ir++++++ +   +kLPLP+++kdYL++++y
   Q: 487  TNPVSRFMQVRSLQYLCRFVIRQYTRIDLI---QKLPLPNKMKDYLQEKHY 534
           5788999********************888...***************997 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

MKKISLKTIR KSFNLNKSKD ESDFVVVQQP SLSEFGKDDS LFGSCYGKDL ASCEVNSEDE 60
KGGKNRSKSE SLMGTLKRRL SAKQKQKGKG STPSVSSADD DTFSSSSAPI TFKDVRAQRP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGAAAA TTAGTCTCAA AACAATTCGC AAGTCCTTTA ACTTAAATAA AAGTAAAGAT 60
GAAAGTGACT TTGTAGTGGT TCAGCAGCCA TCGTTAAGTG AATTTGGAAA AGATGACTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028421--SOCS6
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0001772--C:immunological synapse
GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0050868--P:negative regulation of T cell activation
GO:0010498--P:proteasomal protein catabolic process
GO:0040008--P:regulation of growth

KEGG

apla:101800355

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001911	Ailuropoda melanoleuca	90.84	0.00e+00	910.00
IUUC-Aca-004782	Anolis carolinensis	93.83	0.00e+00	915.00
IUUC-Ame-011790	Astyanax mexicanus	70.20	0.00e+00	649.00
IUUC-Bta-012579	Bos taurus	94.20	2.00e-108	385.00
IUUC-Cel-018643	Caenorhabditis elegans	33.59	8.00e-12	63.20
IUUC-Cja-019528	Callithrix jacchus	90.84	0.00e+00	956.00
IUUC-Cfa-020678	Canis familiaris	90.47	0.00e+00	935.00
IUUC-Cpo-021947	Cavia porcellus	90.47	0.00e+00	961.00
IUUC-Csa-023935	Chlorocebus sabaeus	90.28	0.00e+00	930.00
IUUC-Cho-024477	Choloepus hoffmanni	88.22	0.00e+00	931.00
IUUC-Cin-025413	Ciona intestinalis	68.24	2.00e-66	245.00
IUUC-Csv-026247	Ciona savignyi	67.47	4.00e-65	241.00
IUUC-Cne-026906	Cryptococcus neoformans	22.92	1.00e+00	28.10
IUUC-Dre-027636	Danio rerio	70.34	0.00e+00	650.00
IUUC-Dno-029048	Dasypus novemcinctus	90.84	0.00e+00	934.00
IUUC-Dor-030401	Dipodomys ordii	86.57	0.00e+00	875.00
IUUC-Dme-031876	Drosophila melanogaster	46.34	9.00e-38	152.00
IUUC-Ete-033116	Echinops telfairi	48.76	6.00e-58	217.00
IUUC-Eca-033825	Equus caballus	91.40	0.00e+00	892.00
IUUC-Fca-036253	Felis catus	89.53	0.00e+00	835.00
IUUC-Fal-037614	Ficedula albicollis	98.31	0.00e+00	964.00
IUUC-Fox-037898	Fusarium oxysporum	28.05	5.00e-03	34.70
IUUC-Gmo-038928	Gadus morhua	68.75	0.00e+00	673.00
IUUC-Gga-040177	Gallus gallus	99.06	0.00e+00	972.00
IUUC-Gac-042263	Gasterosteus aculeatus	71.40	0.00e+00	717.00
IUUC-Ggo-045288	Gorilla gorilla	90.09	0.00e+00	932.00
IUUC-Hsa-046409	Homo sapiens	90.47	0.00e+00	933.00
IUUC-Itr-048996	Ictidomys tridecemlineatus	88.60	0.00e+00	887.00
IUUC-Lch-050354	Latimeria chalumnae	87.31	0.00e+00	897.00
IUUC-Loc-052319	Lepisosteus oculatus	82.46	0.00e+00	842.00
IUUC-Laf-054070	Loxodonta africana	88.41	0.00e+00	888.00
IUUC-Mcc-055045	Macaca mulatta	89.91	0.00e+00	926.00
IUUC-Meu-055917	Macropus eugenii	94.77	0.00e+00	1003.00
IUUC-Mga-059273	Meleagris gallopavo	99.06	0.00e+00	971.00
IUUC-Mmr-061597	Microcebus murinus	90.28	0.00e+00	929.00
IUUC-Mdo-062492	Monodelphis domestica	71.43	6.00e-122	429.00
IUUC-Mmu-063374	Mus musculus	79.18	0.00e+00	805.00
IUUC-Mpu-065967	Mustela putorius furo	86.17	0.00e+00	868.00
IUUC-Mlu-067532	Myotis lucifugus	88.97	0.00e+00	893.00
IUUC-Nle-069373	Nomascus leucogenys	90.65	0.00e+00	933.00
IUUC-Opr-070873	Ochotona princeps	87.85	0.00e+00	929.00
IUUC-Ont-072498	Oreochromis niloticus	71.40	0.00e+00	746.00
IUUC-Oan-072943	Ornithorhynchus anatinus	73.80	2.00e-101	361.00
IUUC-Ocu-073870	Oryctolagus cuniculus	89.16	0.00e+00	910.00
IUUC-Ola-086866	Oryzias latipes	88.48	7.00e-105	372.00
IUUC-Oga-089057	Otolemur garnettii	87.85	0.00e+00	882.00
IUUC-Oar-089841	Ovis aries	58.77	3.00e-159	554.00
IUUC-Ptr-091054	Pan troglodytes	90.47	0.00e+00	932.00
IUUC-Pma-094253	Petromyzon marinus	44.44	7.00e-104	370.00
IUUC-Pfo-097179	Poecilia formosa	65.99	2.00e-180	625.00
IUUC-Pab-097702	Pongo abelii	90.65	0.00e+00	933.00
IUUC-Pca-100671	Procavia capensis	79.45	3.00e-121	428.00
IUUC-Rno-106044	Rattus norvegicus	77.54	0.00e+00	794.00
IUUC-Sha-107139	Sarcophilus harrisii	94.18	0.00e+00	919.00
IUUC-Smo-108823	Selaginella moellendorffii	33.96	4.50e-02	31.20
IUUC-Ssc-115343	Sus scrofa	87.66	0.00e+00	909.00
IUUC-Tgu-117061	Taeniopygia guttata	98.88	0.00e+00	970.00
IUUC-Tni-119829	Tetraodon nigroviridis	68.21	0.00e+00	658.00
IUUC-Tae-123723	Triticum aestivum	34.15	5.40e-01	29.60
IUUC-Ttr-129148	Tursiops truncatus	87.29	0.00e+00	860.00
IUUC-Vpa-130780	Vicugna pacos	84.86	0.00e+00	834.00
IUUC-Vvi-130966	Vitis vinifera	32.69	6.90e-02	30.80
IUUC-Xtr-132513	Xenopus tropicalis	86.73	0.00e+00	887.00
IUUC-Xma-133904	Xiphophorus maculatus	70.24	0.00e+00	681.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence