iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132283

UUCD1 version

UUC-XeT-00935

Ensembl Protein ID

ENSXETP00000031072.2

UniProt Accession

Q5XGC0; FXL15_XENTR

Genbank Protein ID

CAJ82498.1; AAH84522.1

Protein Name

F-box/LRR-repeat protein 15

Genbank Nucleotide ID

CR762261; BC084522

Gene Name

fbxl15; TGas057g02.1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000014210.2	ENSXETT00000031072.2	ENSXETP00000031072.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	56.51	2.00e-98	356.00	IUUC-Hsa-046910

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Xenopus tropicalis

Functional Description
(View)

Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXL15).

Protein Sequence
(Fasta)

MAKDEDNSSV HLLDLPWEDV LVPHILRNLP LRHILSLQRV SKPFQSLVHL YLANCRHFDS 60
TQLGSQLPKS TFSELLRNNT VLQKLDLQSC CDWLTDKELL PVIGQNHHLI HINLNSCGQL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGCAGGGAA ATGGTCCATT CGAGTCAGGG GCAGGTCATT TCTTTCCATA CATGGTTTCC 60
TTTCAAACAG GAATCAGGTA TGTTAATGTT AAAAAAAAAA TATGTCTGTT AATTTCTGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0433--Leucine-rich repeat
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp

Pfam

PF00646--F-box

SMART

SM00367--LRR_CC

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0030282--P:bone mineralization
GO:0009953--P:dorsal/ventral pattern formation
GO:0000086--P:G2/M transition of mitotic cell cycle
GO:0030513--P:positive regulation of BMP signaling pathway
GO:0016567--P:protein ubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

xtr:496536

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002259	Ailuropoda melanoleuca	54.11	7.00e-86	310.00
IUUC-Apl-003471	Anas platyrhynchos	75.11	1.00e-90	325.00
IUUC-Aca-005211	Anolis carolinensis	68.97	5.00e-108	384.00
IUUC-Ame-011477	Astyanax mexicanus	64.85	1.00e-110	392.00
IUUC-Bta-013461	Bos taurus	56.51	4.00e-99	353.00
IUUC-Cja-019278	Callithrix jacchus	56.51	2.00e-88	318.00
IUUC-Cfa-020248	Canis familiaris	56.85	8.00e-92	329.00
IUUC-Cpo-021313	Cavia porcellus	54.14	3.00e-80	291.00
IUUC-Csa-023633	Chlorocebus sabaeus	56.51	7.00e-99	353.00
IUUC-Cin-025760	Ciona intestinalis	34.12	7.00e-35	140.00
IUUC-Csv-025866	Ciona savignyi	31.54	2.00e-35	142.00
IUUC-Dre-027366	Danio rerio	66.55	1.00e-109	389.00
IUUC-Dno-029700	Dasypus novemcinctus	56.85	1.00e-91	329.00
IUUC-Dor-031069	Dipodomys ordii	55.33	5.00e-95	340.00
IUUC-Dme-031701	Drosophila melanogaster	30.68	1.00e-27	116.00
IUUC-Ete-032998	Echinops telfairi	55.14	7.00e-81	293.00
IUUC-Eca-034140	Equus caballus	56.51	5.00e-87	313.00
IUUC-Fca-035431	Felis catus	56.51	4.00e-91	327.00
IUUC-Fal-036960	Ficedula albicollis	75.80	3.00e-116	411.00
IUUC-Gmo-039411	Gadus morhua	70.57	3.00e-115	407.00
IUUC-Gga-040351	Gallus gallus	70.82	8.00e-108	382.00
IUUC-Gac-041972	Gasterosteus aculeatus	69.86	9.00e-106	375.00
IUUC-Ggo-044538	Gorilla gorilla	56.51	2.00e-88	318.00
IUUC-Hsa-046910	Homo sapiens	56.51	6.00e-88	317.00
IUUC-Itr-048011	Ictidomys tridecemlineatus	56.51	1.00e-90	325.00
IUUC-Lch-049710	Latimeria chalumnae	70.21	8.00e-116	409.00
IUUC-Loc-052288	Lepisosteus oculatus	68.88	1.00e-114	405.00
IUUC-Laf-053590	Loxodonta africana	51.88	2.00e-82	298.00
IUUC-Meu-056548	Macropus eugenii	61.51	2.00e-99	354.00
IUUC-Mga-059794	Meleagris gallopavo	72.60	2.00e-109	388.00
IUUC-Mmr-060829	Microcebus murinus	57.88	2.00e-93	335.00
IUUC-Mdo-062207	Monodelphis domestica	60.62	7.00e-103	366.00
IUUC-Mmu-063353	Mus musculus	56.51	1.00e-91	328.00
IUUC-Mpu-065841	Mustela putorius furo	56.51	4.00e-91	327.00
IUUC-Mlu-068035	Myotis lucifugus	57.09	1.00e-89	322.00
IUUC-Nle-069269	Nomascus leucogenys	56.51	9.00e-89	319.00
IUUC-Opr-070289	Ochotona princeps	53.71	2.00e-62	232.00
IUUC-Ont-072581	Oreochromis niloticus	68.15	4.00e-113	400.00
IUUC-Oan-073529	Ornithorhynchus anatinus	65.92	1.00e-80	292.00
IUUC-Ocu-074827	Oryctolagus cuniculus	57.19	5.00e-96	343.00
IUUC-Ola-087306	Oryzias latipes	69.52	1.00e-113	402.00
IUUC-Oga-088596	Otolemur garnettii	55.52	4.00e-85	307.00
IUUC-Oar-089473	Ovis aries	51.64	4.00e-55	207.00
IUUC-Ptr-091197	Pan troglodytes	56.51	2.00e-88	318.00
IUUC-Pan-092908	Papio anubis	56.16	2.00e-95	341.00
IUUC-Psi-093318	Pelodiscus sinensis	65.57	9.00e-75	273.00
IUUC-Pfo-097479	Poecilia formosa	70.45	4.00e-116	410.00
IUUC-Pab-097744	Pongo abelii	56.16	3.00e-89	322.00
IUUC-Pca-100930	Procavia capensis	55.48	3.00e-85	308.00
IUUC-Pva-102763	Pteropus vampyrus	46.21	6.00e-28	117.00
IUUC-Rno-105651	Rattus norvegicus	56.85	1.00e-94	338.00
IUUC-Tgu-117097	Taeniopygia guttata	75.44	3.00e-115	407.00
IUUC-Tru-118057	Takifugu rubripes	70.21	2.00e-114	405.00
IUUC-Tni-120693	Tetraodon nigroviridis	65.75	9.00e-109	385.00
IUUC-Tbe-127992	Tupaia belangeri	60.85	1.00e-65	243.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence