• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Tag Content
iUUCD ID IUUC-Gga-040802
Ensembl Protein ID ENSGALP00000045209.1
UniProt Accession Q5F3R2; KDM5B_CHICK
Genbank Protein ID CAH65222.1
Protein Name Lysine-specific demethylase 5B; Histone demethylase JARID1B; Jumonji/ARID domain-containing protein 1B
Genbank Nucleotide ID AJ851588
Gene Name KDM5B; JARID1B; RCJMB04_9d3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSGALG00000038948.2 ENSGALT00000056356.1 ENSGALP00000045209.1
ENSGALG00000038948.2 ENSGALT00000071675.2 ENSGALP00000056668.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 2.60e-17 63.1 286 332
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           vCl+Cg+g +++  l+ C+ C++ +H  Cl ++   ++p+ + w Cp+C 
   Q: 286  VCLLCGSGNDED-RLLLCDGCDDSYHTFCLIPP-LHDVPKGD-WRCPQCL 332
           8********988.6*******************.*******7.******5 PP
   
Organism Gallus gallus
Functional Description
(View)

Functional Description


     Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor. May repress the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2.
 Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor. May repress the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2.
Protein Sequence
(Fasta)
MAEFLPPPEC PVFEPSWEEF ADPFAFIHKI RPIAEQTGIC KVRPPPDWQP PFACDVDKLH 60
FTPRIQRLNE LEAQTRVKLN FLDQIAKFWE LQGCTLKIPH VERKILDLFQ LNRLVAEEGG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Gga-040802|E3,PHD|Gallus gallus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGGCGCTCCC CGAACCAGCG GTGCTGGGGG GAGCGGTGCG GGGCAGGAGG TCCGCGGGGC 60
GCGCACAAAG GCGCGGGGCC GCCGCTCGGA GCTCCCGGCT CGGCTCGTTC CGCGGCCGGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Gga-040802|E3,PHD|Gallus gallus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0090--Biological rhythms
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0223--Dioxygenase
KW-0408--Iron
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0560--Oxidoreductase
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51011--ARID
PS51184--JMJC
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
Pfam

PF01388--ARID
PF02373--JmjC
PF02375--JmjN
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2
SMART

SM00501--BRIGHT
SM00558--JmjC
SM00545--JmjN
SM00249--PHD
Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0034648--F:histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034647--F:histone demethylase activity (H3-trimethyl-K4 specific)
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0008270--F:zinc ion binding
GO:0034720--P:histone H3-K4 demethylation
GO:0006355--P:regulation of transcription, DNA-templated
GO:0048511--P:rhythmic process
GO:0006351--P:transcription, DNA-templated
KEGG gga:421168
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000552 Aegilops tauschii 33.62 2.00e-94 341.00
IUUC-Aml-001963 Ailuropoda melanoleuca 83.36 0.00e+00 2336.00
IUUC-Apl-003770 Anas platyrhynchos 93.83 0.00e+00 2377.00
IUUC-Aca-004867 Anolis carolinensis 83.13 0.00e+00 2489.00
IUUC-Acl-008162 Aspergillus clavatus 30.81 5.00e-112 399.00
IUUC-Ani-009139 Aspergillus nidulans 31.66 1.00e-112 401.00
IUUC-Ame-010620 Astyanax mexicanus 62.69 0.00e+00 1856.00
IUUC-Bgr-012241 Blumeria graminis 29.08 7.00e-108 385.00
IUUC-Bta-012733 Bos taurus 81.64 0.00e+00 2300.00
IUUC-Bci-013992 Botrytis cinerea 31.37 3.00e-111 397.00
IUUC-Bdi-014050 Brachypodium distachyon 30.67 6.00e-121 429.00
IUUC-Bol-015336 Brassica oleracea 34.43 3.00e-15 78.60
IUUC-Bra-017998 Brassica rapa 33.33 6.00e-14 74.30
IUUC-Cja-019050 Callithrix jacchus 83.47 0.00e+00 2430.00
IUUC-Cfa-021015 Canis familiaris 83.41 0.00e+00 2331.00
IUUC-Cpo-022340 Cavia porcellus 83.21 0.00e+00 2306.00
IUUC-Csa-023441 Chlorocebus sabaeus 83.84 0.00e+00 2419.00
IUUC-Cho-024823 Choloepus hoffmanni 89.08 0.00e+00 1560.00
IUUC-Cgl-026613 Colletotrichum gloeosporioides 31.06 3.00e-112 400.00
IUUC-Cne-026851 Cryptococcus neoformans 29.61 1.00e-109 392.00
IUUC-Dre-027707 Danio rerio 61.91 0.00e+00 1794.00
IUUC-Dno-028978 Dasypus novemcinctus 83.95 0.00e+00 2417.00
IUUC-Dor-030854 Dipodomys ordii 74.21 0.00e+00 1583.00
IUUC-Ete-032760 Echinops telfairi 80.51 0.00e+00 1648.00
IUUC-Eca-034370 Equus caballus 83.55 0.00e+00 2272.00
IUUC-Eeu-035012 Erinaceus europaeus 67.98 0.00e+00 1664.00
IUUC-Fca-035494 Felis catus 83.64 0.00e+00 2338.00
IUUC-Fal-037631 Ficedula albicollis 90.66 0.00e+00 2564.00
IUUC-Fox-037694 Fusarium oxysporum 32.16 2.00e-99 357.00
IUUC-Fso-038127 Fusarium solani 30.16 8.00e-109 389.00
IUUC-Gmo-039522 Gadus morhua 67.06 0.00e+00 1601.00
IUUC-Ggr-039929 Gaeumannomyces graminis 29.04 3.00e-105 377.00
IUUC-Gac-041461 Gasterosteus aculeatus 61.16 0.00e+00 1805.00
IUUC-Gma-042675 Glycine max 32.68 2.00e-103 370.00
IUUC-Ggo-044856 Gorilla gorilla 67.14 0.00e+00 1770.00
IUUC-Hsa-045888 Homo sapiens 81.78 0.00e+00 2422.00
IUUC-Hvu-047583 Hordeum vulgare 39.00 1.00e-16 82.00
IUUC-Itr-048297 Ictidomys tridecemlineatus 83.91 0.00e+00 2397.00
IUUC-Lch-050483 Latimeria chalumnae 65.71 0.00e+00 1951.00
IUUC-Loc-052550 Lepisosteus oculatus 73.34 0.00e+00 2024.00
IUUC-Laf-053761 Loxodonta africana 82.72 0.00e+00 2315.00
IUUC-Mcc-055505 Macaca mulatta 81.84 0.00e+00 2426.00
IUUC-Mpo-057317 Magnaporthe poae 34.07 5.00e-105 376.00
IUUC-Mga-059358 Meleagris gallopavo 97.01 0.00e+00 2731.00
IUUC-Mmr-060863 Microcebus murinus 83.51 0.00e+00 2396.00
IUUC-Mdo-061957 Monodelphis domestica 84.82 0.00e+00 2504.00
IUUC-Mmu-063944 Mus musculus 82.48 0.00e+00 2369.00
IUUC-Mac-065069 Musa acuminata 31.03 3.00e-08 55.50
IUUC-Mpu-066719 Mustela putorius furo 82.23 0.00e+00 2394.00
IUUC-Mlu-067366 Myotis lucifugus 78.28 0.00e+00 2233.00
IUUC-Nfi-068430 Neosartorya fischeri 29.81 1.00e-108 388.00
IUUC-Ncr-068763 Neurospora crassa 30.43 3.00e-112 400.00
IUUC-Nle-069256 Nomascus leucogenys 80.88 0.00e+00 2385.00
IUUC-Ont-071756 Oreochromis niloticus 61.32 0.00e+00 1800.00
IUUC-Oan-073568 Ornithorhynchus anatinus 85.52 0.00e+00 2519.00
IUUC-Ocu-073961 Oryctolagus cuniculus 82.11 0.00e+00 2358.00
IUUC-Oba-075388 Oryza barthii 28.80 4.00e-83 303.00
IUUC-Ogl-077886 Oryza glaberrima 35.48 1.00e-16 81.60
IUUC-Ogu-079040 Oryza glumaepatula 28.39 4.00e-83 303.00
IUUC-Oin-079273 Oryza indica 50.00 2.00e-13 68.60
IUUC-Olo-080668 Oryza longistaminata 35.48 2.00e-16 82.00
IUUC-Ome-081764 Oryza meridionalis 30.30 4.00e-101 363.00
IUUC-Oni-083012 Oryza nivara 28.80 8.00e-83 302.00
IUUC-Opu-083164 Oryza punctata 34.90 1.00e-98 355.00
IUUC-Oru-084630 Oryza rufipogon 28.78 8.00e-84 306.00
IUUC-Osa-085487 Oryza sativa 38.83 1.00e-16 81.60
IUUC-Ola-086448 Oryzias latipes 59.92 0.00e+00 1733.00
IUUC-Oga-088501 Otolemur garnettii 79.01 0.00e+00 1971.00
IUUC-Oar-090162 Ovis aries 80.94 0.00e+00 2284.00
IUUC-Ptr-090816 Pan troglodytes 81.97 0.00e+00 2435.00
IUUC-Pan-092764 Papio anubis 83.84 0.00e+00 2420.00
IUUC-Psi-093918 Pelodiscus sinensis 86.02 0.00e+00 2259.00
IUUC-Pfo-096777 Poecilia formosa 61.70 0.00e+00 1835.00
IUUC-Pab-097854 Pongo abelii 83.78 0.00e+00 1983.00
IUUC-Pca-100241 Procavia capensis 77.88 0.00e+00 1472.00
IUUC-Ppe-101504 Prunus persica 32.88 5.00e-103 369.00
IUUC-Pva-103035 Pteropus vampyrus 77.95 0.00e+00 2010.00
IUUC-Pgr-103434 Puccinia graminis 33.54 8.00e-28 117.00
IUUC-Rno-105574 Rattus norvegicus 81.25 0.00e+00 2320.00
IUUC-Sce-106207 Saccharomyces cerevisiae 35.59 1.00e-74 273.00
IUUC-Ssl-108489 Sclerotinia sclerotiorum 31.64 4.00e-114 406.00
IUUC-Sly-111298 Solanum lycopersicum 42.89 3.00e-101 363.00
IUUC-Sar-113477 Sorex araneus 82.26 0.00e+00 2179.00
IUUC-Ssc-116132 Sus scrofa 85.46 0.00e+00 2202.00
IUUC-Tgu-117452 Taeniopygia guttata 91.69 0.00e+00 2585.00
IUUC-Tru-117561 Takifugu rubripes 63.07 0.00e+00 1726.00
IUUC-Tsy-119271 Tarsius syrichta 81.73 0.00e+00 1816.00
IUUC-Tni-119650 Tetraodon nigroviridis 64.96 0.00e+00 1748.00
IUUC-Tca-121478 Theobroma cacao 42.12 2.00e-102 368.00
IUUC-Tae-125894 Triticum aestivum 29.95 7.00e-112 399.00
IUUC-Tur-126632 Triticum urartu 33.10 7.00e-95 342.00
IUUC-Tbe-127890 Tupaia belangeri 74.14 0.00e+00 1206.00
IUUC-Ttr-128546 Tursiops truncatus 82.38 0.00e+00 1837.00
IUUC-Vda-129733 Verticillium dahliae 29.42 3.00e-105 377.00
IUUC-Vpa-130432 Vicugna pacos 80.46 0.00e+00 1402.00
IUUC-Vvi-131071 Vitis vinifera 31.40 1.00e-82 301.00
IUUC-Xtr-132008 Xenopus tropicalis 71.56 0.00e+00 2087.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved