iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045421

UUCD1 version

UUC-GoG-00834

Ensembl Protein ID

ENSGGOP00000025463.1

UniProt Accession

G3SBI7; G3SBI7_GORGO

Protein Name

Uncharacterized protein

Gene Name

RNF126

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000015912.2	ENSGGOT00000025668.1	ENSGGOP00000026325.1
ENSGGOG00000015912.2	ENSGGOT00000030605.1	ENSGGOP00000025463.1
ENSGGOG00000015912.2	ENSGGOT00000015968.2	ENSGGOP00000015523.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.00e-06	28.6	229	259

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf...kdgplvlpCgHvfhadClqkw 29
           C++C++d+   ++ ++ lpC+H+fh  C+  w
   Q: 229  CPVCKDDYalgER-VRQLPCNHLFHDGCIVPW 259
           ********99777.***************988 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MAEASPHPGR YFCHCCSVEI VPRLPDYICP RCESGFIEEL PEETRSTENG SAPSTAPTDQ 60
SRPPLEHVDQ HLFTLPQGYG QFAFGIFDDS FEIPTFPPGA QADDGRDPES RRERDHPSRH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGAGG CGTCGCCGCA TCCCGGACGG TACTTCTGCC ACTGCTGCTC CGTGGAGATC 60
GTCCCGCGCC TGCCGGTGAG GCCCGGGCCG GGGCGGCGGG CGGCAGGGTC TGTGCCGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042059--P:negative regulation of epidermal growth factor receptor signaling pathway
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0042127--P:regulation of cell proliferation
GO:0042147--P:retrograde transport, endosome to Golgi
GO:0071629--P:ubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002001	Ailuropoda melanoleuca	91.85	9.00e-128	449.00
IUUC-Apl-003778	Anas platyrhynchos	74.35	5.00e-79	287.00
IUUC-Aca-005166	Anolis carolinensis	76.28	1.00e-104	372.00
IUUC-Ame-010626	Astyanax mexicanus	69.55	1.00e-98	352.00
IUUC-Bta-012808	Bos taurus	90.41	5.00e-119	420.00
IUUC-Cja-019575	Callithrix jacchus	88.89	3.00e-119	421.00
IUUC-Cfa-020142	Canis familiaris	91.09	2.00e-112	398.00
IUUC-Cpo-022451	Cavia porcellus	89.63	7.00e-125	439.00
IUUC-Csa-023433	Chlorocebus sabaeus	95.90	1.00e-151	528.00
IUUC-Dre-027400	Danio rerio	70.00	1.00e-98	352.00
IUUC-Dno-029349	Dasypus novemcinctus	88.83	2.00e-87	315.00
IUUC-Dor-030103	Dipodomys ordii	91.43	2.00e-102	365.00
IUUC-Eca-034240	Equus caballus	90.24	4.00e-87	313.00
IUUC-Fal-037027	Ficedula albicollis	77.73	4.00e-86	310.00
IUUC-Gmo-039694	Gadus morhua	68.63	3.00e-104	371.00
IUUC-Gga-040682	Gallus gallus	80.00	3.00e-106	377.00
IUUC-Gac-041369	Gasterosteus aculeatus	65.95	9.00e-96	343.00
IUUC-Hsa-046723	Homo sapiens	97.76	3.00e-143	500.00
IUUC-Itr-048435	Ictidomys tridecemlineatus	91.50	3.00e-108	384.00
IUUC-Lch-050071	Latimeria chalumnae	77.78	2.00e-107	382.00
IUUC-Loc-052470	Lepisosteus oculatus	59.70	2.00e-76	278.00
IUUC-Laf-054249	Loxodonta africana	70.43	4.00e-67	247.00
IUUC-Mcc-055739	Macaca mulatta	97.01	1.00e-142	498.00
IUUC-Meu-056622	Macropus eugenii	65.66	8.00e-50	190.00
IUUC-Mga-059349	Meleagris gallopavo	77.27	2.00e-93	335.00
IUUC-Mmr-060653	Microcebus murinus	92.22	3.00e-135	474.00
IUUC-Mdo-062442	Monodelphis domestica	85.56	1.00e-126	446.00
IUUC-Mmu-064148	Mus musculus	90.74	1.00e-125	442.00
IUUC-Mpu-065917	Mustela putorius furo	88.42	1.00e-113	402.00
IUUC-Mlu-067495	Myotis lucifugus	91.85	3.00e-128	451.00
IUUC-Nle-069274	Nomascus leucogenys	97.01	9.00e-133	466.00
IUUC-Opr-070359	Ochotona princeps	88.02	5.00e-85	306.00
IUUC-Ont-071505	Oreochromis niloticus	71.21	3.00e-102	364.00
IUUC-Oan-073225	Ornithorhynchus anatinus	79.50	2.00e-96	345.00
IUUC-Ola-086315	Oryzias latipes	65.12	2.00e-95	342.00
IUUC-Oga-088067	Otolemur garnettii	91.48	9.00e-122	429.00
IUUC-Ptr-091404	Pan troglodytes	99.55	5.00e-118	416.00
IUUC-Pan-092424	Papio anubis	87.42	2.00e-147	514.00
IUUC-Psi-093171	Pelodiscus sinensis	80.97	7.00e-97	346.00
IUUC-Pma-094408	Petromyzon marinus	43.73	2.00e-53	202.00
IUUC-Pfo-097402	Poecilia formosa	69.06	2.00e-98	351.00
IUUC-Pab-097834	Pongo abelii	97.32	3.00e-114	404.00
IUUC-Pca-100442	Procavia capensis	89.39	1.00e-82	298.00
IUUC-Pva-103240	Pteropus vampyrus	83.59	4.00e-139	487.00
IUUC-Rno-105203	Rattus norvegicus	91.11	4.00e-126	444.00
IUUC-Sha-107638	Sarcophilus harrisii	83.00	1.00e-111	395.00
IUUC-Tgu-117502	Taeniopygia guttata	81.06	3.00e-102	364.00
IUUC-Tru-117681	Takifugu rubripes	68.30	2.00e-98	352.00
IUUC-Tni-120092	Tetraodon nigroviridis	63.26	1.00e-92	332.00
IUUC-Ttr-128843	Tursiops truncatus	91.48	2.00e-126	445.00
IUUC-Xtr-132815	Xenopus tropicalis	52.45	2.00e-75	275.00
IUUC-Xma-133481	Xiphophorus maculatus	68.68	5.00e-98	350.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence