iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054249

UUCD1 version

UUC-LoA-00719

Ensembl Protein ID

ENSLAFP00000019017.1

UniProt Accession

G3TTV9; G3TTV9_LOXAF

Protein Name

Uncharacterized protein

Gene Name

RNF126

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000028994.1	ENSLAFT00000035352.1	ENSLAFP00000019017.1
ENSLAFG00000028994.1	ENSLAFT00000031066.1	ENSLAFP00000028577.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	70.82	2.00e-67	253.00	IUUC-Hsa-046723
UBD/ZnF/ZnF_A20	70.82	2.00e-67	253.00	IUUC-Hsa-046723

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MAEASPQPGR YFCHCCLVEI VPRLPDYICP RCESGFIEEL LEETRSTESG PAPSTAPTDQ 60
SRQPLENVDQ HLFTLPQSYG QFAFGIFDDS FEIPTFTPGA QPDDSRDPES RREREHPSRH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGAGG CGTCGCCGCA GCCCGGACGG TACTTCTGCC ACTGCTGCTT GGTCGAGATC 60
GTCCCGCGCC TGCCGGTGAG GCCCGACCGG GGGCGGCGGC GGGCGGGCGG CGGGACCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF17123--zf-RING_11

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042059--P:negative regulation of epidermal growth factor receptor signaling pathway
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0042127--P:regulation of cell proliferation
GO:0042147--P:retrograde transport, endosome to Golgi
GO:0071629--P:ubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002001	Ailuropoda melanoleuca	69.38	2.00e-78	285.00
IUUC-Aca-005166	Anolis carolinensis	54.62	8.00e-63	233.00
IUUC-Bta-012808	Bos taurus	69.50	3.00e-72	265.00
IUUC-Cja-019575	Callithrix jacchus	64.86	2.00e-69	255.00
IUUC-Cfa-020142	Canis familiaris	66.38	2.00e-63	235.00
IUUC-Cpo-022451	Cavia porcellus	69.77	1.00e-79	289.00
IUUC-Csa-023433	Chlorocebus sabaeus	70.04	5.00e-97	347.00
IUUC-Dre-027400	Danio rerio	54.23	3.00e-60	224.00
IUUC-Dor-030103	Dipodomys ordii	69.10	3.00e-57	215.00
IUUC-Gmo-039694	Gadus morhua	52.06	9.00e-68	249.00
IUUC-Gga-040682	Gallus gallus	60.77	3.00e-66	244.00
IUUC-Ggo-045421	Gorilla gorilla	70.43	8.00e-87	313.00
IUUC-Hsa-046723	Homo sapiens	70.82	1.00e-88	318.00
IUUC-Itr-048435	Ictidomys tridecemlineatus	69.20	2.00e-63	235.00
IUUC-Lch-050071	Latimeria chalumnae	62.40	4.00e-71	261.00
IUUC-Loc-052470	Lepisosteus oculatus	53.94	9.00e-56	209.00
IUUC-Mcc-055739	Macaca mulatta	70.82	7.00e-89	320.00
IUUC-Meu-056622	Macropus eugenii	80.49	5.00e-39	154.00
IUUC-Mmr-060653	Microcebus murinus	71.54	4.00e-90	324.00
IUUC-Mdo-062442	Monodelphis domestica	65.38	5.00e-83	300.00
IUUC-Mmu-064148	Mus musculus	70.77	3.00e-81	294.00
IUUC-Mpu-065917	Mustela putorius furo	64.78	3.00e-64	238.00
IUUC-Mlu-067495	Myotis lucifugus	70.54	7.00e-82	296.00
IUUC-Nle-069274	Nomascus leucogenys	70.82	1.00e-78	286.00
IUUC-Opr-070359	Ochotona princeps	62.39	3.00e-45	174.00
IUUC-Oan-073225	Ornithorhynchus anatinus	57.87	1.00e-56	213.00
IUUC-Oga-088067	Otolemur garnettii	72.87	6.00e-77	280.00
IUUC-Ptr-091404	Pan troglodytes	73.79	1.00e-72	265.00
IUUC-Pan-092424	Papio anubis	70.82	1.00e-88	319.00
IUUC-Psi-093171	Pelodiscus sinensis	60.76	8.00e-57	213.00
IUUC-Pab-097834	Pongo abelii	71.84	9.00e-69	252.00
IUUC-Pva-103240	Pteropus vampyrus	68.99	5.00e-88	317.00
IUUC-Rno-105203	Rattus norvegicus	69.62	2.00e-79	289.00
IUUC-Sha-107638	Sarcophilus harrisii	61.73	2.00e-68	252.00
IUUC-Tgu-117502	Taeniopygia guttata	60.77	2.00e-59	222.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence