iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000015021.4	ENSCAFT00000023833.4	ENSCAFP00000022125.3
ENSCAFG00000015021.4	ENSCAFT00000047257.2	ENSCAFP00000040152.1
ENSCAFG00000015021.4	ENSCAFT00000044288.1	ENSCAFP00000042980.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.90e-111	372.2	296	922

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS+LQcLsn+p+l+e++l+ ++ e+ln  np ++kge+++++++l+++ w+++++++ p+ ++++++++a++f gy+
   Q: 296  CGLTNLGNTCFMNSALQCLSNVPQLTEYFLKnHYLEELNFCNPLGMKGEIAEAYADLVKQAWSGHHRSIVPHVFKTKVGHFASQFLGYQ 384
           7*****************************98999****************************************************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde...aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           q+D+qE+l+flld+l+e+l++ k+k++ e+++++ +  ++    a++++k++n+s+i+d+F+g +ks+++c++c+nvs++++pf++ls+
   Q: 385  QHDSQELLSFLLDGLHEDLNRVKKKEYVELCDAAGRPDQEVaqeAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSV 473
           *****************************998874333322555********************************************* PP
   S: 175  pvpgkeetkke.............................................................................. 185
           p+p ++++ +e                                                                              
   Q: 474  PLPVSHKRVMEvffvsmdprrkpeqhrlvvpkkgkisdlcvalakhtgmspermmvadvfshrfykiyqleeslssildrddifiyevs 562
           ******99988****************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 563  grsaigensredvvlpiylrertpardynnsyyglmlfghpllvsvprdrlswdalyhillyrlsryvtrpssddeddgdekgkeeedi 651
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 652  edkdnipkpghvagassqdsgpeqagpssgvaggsrapvdnspgpshwpqrarrkhlftlqtvnsngtsdrstfnedthaqpyiaidwe 740
           ***************************************************************************************** PP
   S: 186  ...............................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeq 243
                                           lq+c+e ft+ e+le+en ++c++ck++q a+kkl+l+ lPe+Li+hLkRfs+++  
   Q: 741  pemkkryydeveaegyvkhdcvgyvlkkapvRLQECIELFTTVETLEKENPWFCPTCKQHQLATKKLDLWMLPETLIIHLKRFSYTK-- 827
           ***********************************************************************************8866.. PP
   S: 244  ksrekinkkvefple.Ldlspfctspeekqke.kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgst 329
            srek+++ vefp++ Ld s+f+++p+++++   +kY+Liav +H+G+l+ GHY++++ n ++g+W +fdD++V++v+e+++++   + 
   Q: 828  FSREKLDTLVEFPIRdLDFSEFVIKPQNESAPeLYKYDLIAVSNHYGGLRDGHYTTFACNkDSGQWHYFDDNSVSPVTENQIES---KA 913
           89*********************999887754489*********************988834566*******************...** PP
   S: 330  aYvlfYkrr 338
           aYvlfY+r+
   Q: 914  AYVLFYQRQ 922
           *******96 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MAVAPWLFGG LCFRFRDQNP EVAVEGPLPI SSCGGCERRT VMAAVAANVA AAAEDREPQR 60
EAVPGLESQW RQIENSESGR ERPLRAGESW FLVEQHWYKR WEVYVQGGDQ DSGTFPGCIN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGTAG CCCCCTGGCT GTTTGGGGGG CTCTGTTTCC GTTTCCGGGA CCAGAATCCG 60
GAAGTGGCCG TTGAGGGGCC TCTTCCTATC TCCAGCTGCG GTGGCTGTGA GAGGAGGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH
PF14533--USP7_C2

SMART

SM00695--DUSP

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001760	Ailuropoda melanoleuca	96.86	0.00e+00	1714.00
IUUC-Aca-004532	Anolis carolinensis	66.82	0.00e+00	1144.00
IUUC-Afu-008878	Aspergillus fumigatus	38.99	5.00e-56	213.00
IUUC-Ate-010323	Aspergillus terreus	37.14	4.00e-57	217.00
IUUC-Bta-013284	Bos taurus	91.89	0.00e+00	1627.00
IUUC-Cja-019746	Callithrix jacchus	84.27	0.00e+00	1509.00
IUUC-Cpo-022535	Cavia porcellus	78.08	0.00e+00	1453.00
IUUC-Csa-023828	Chlorocebus sabaeus	83.78	0.00e+00	1593.00
IUUC-Dre-027398	Danio rerio	63.46	0.00e+00	757.00
IUUC-Dno-028853	Dasypus novemcinctus	88.12	0.00e+00	1386.00
IUUC-Dor-030384	Dipodomys ordii	79.42	0.00e+00	1478.00
IUUC-Eca-033271	Equus caballus	94.46	0.00e+00	1677.00
IUUC-Fca-036012	Felis catus	94.68	0.00e+00	1719.00
IUUC-Fso-038291	Fusarium solani	44.12	8.00e-64	239.00
IUUC-Gmo-038697	Gadus morhua	56.32	0.00e+00	638.00
IUUC-Gac-042574	Gasterosteus aculeatus	55.41	0.00e+00	907.00
IUUC-Hsa-046551	Homo sapiens	83.16	0.00e+00	1594.00
IUUC-Itr-048915	Ictidomys tridecemlineatus	81.10	0.00e+00	1504.00
IUUC-Kpa-049332	Komagataella pastoris	33.10	3.00e-69	257.00
IUUC-Laf-054561	Loxodonta africana	85.07	0.00e+00	1641.00
IUUC-Mcc-054881	Macaca mulatta	83.57	0.00e+00	1592.00
IUUC-Meu-056749	Macropus eugenii	82.65	0.00e+00	926.00
IUUC-Mla-058848	Melampsora laricipopulina	41.99	3.00e-72	267.00
IUUC-Mvi-060324	Microbotryum violaceum	31.99	3.00e-81	297.00
IUUC-Mmr-061400	Microcebus murinus	87.17	0.00e+00	1573.00
IUUC-Mdo-062470	Monodelphis domestica	81.80	0.00e+00	802.00
IUUC-Mmu-063241	Mus musculus	77.16	0.00e+00	1422.00
IUUC-Mpu-066507	Mustela putorius furo	95.47	0.00e+00	1745.00
IUUC-Mlu-066961	Myotis lucifugus	83.37	0.00e+00	1507.00
IUUC-Nle-069284	Nomascus leucogenys	84.83	0.00e+00	1543.00
IUUC-Ont-071847	Oreochromis niloticus	59.03	0.00e+00	992.00
IUUC-Oan-073387	Ornithorhynchus anatinus	72.20	0.00e+00	1238.00
IUUC-Ocu-074066	Oryctolagus cuniculus	81.72	0.00e+00	1531.00
IUUC-Oga-088424	Otolemur garnettii	85.49	0.00e+00	1538.00
IUUC-Oar-089732	Ovis aries	87.88	0.00e+00	1668.00
IUUC-Pan-092292	Papio anubis	84.17	0.00e+00	1588.00
IUUC-Pab-098779	Pongo abelii	76.85	0.00e+00	1320.00
IUUC-Pca-100851	Procavia capensis	84.44	0.00e+00	976.00
IUUC-Pva-103244	Pteropus vampyrus	90.52	0.00e+00	1650.00
IUUC-Ptt-103847	Puccinia triticina	36.29	4.00e-64	240.00
IUUC-Rno-105100	Rattus norvegicus	77.95	0.00e+00	1429.00
IUUC-Sha-107502	Sarcophilus harrisii	81.15	0.00e+00	918.00
IUUC-Spo-108291	Schizosaccharomyces pombe	32.57	9.00e-77	281.00
IUUC-Smo-108686	Selaginella moellendorffii	38.63	2.00e-108	386.00
IUUC-Ssc-116345	Sus scrofa	93.83	0.00e+00	1712.00
IUUC-Tru-117788	Takifugu rubripes	57.69	0.00e+00	943.00
IUUC-Tsy-119414	Tarsius syrichta	77.57	0.00e+00	1111.00
IUUC-Tni-120799	Tetraodon nigroviridis	60.26	0.00e+00	739.00
IUUC-Tvi-122422	Trichoderma virens	41.54	2.00e-57	218.00
IUUC-Tme-127062	Tuber melanosporum	34.37	4.00e-80	293.00
IUUC-Tbe-128081	Tupaia belangeri	87.34	0.00e+00	984.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence