iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118669

UUCD1 version

UUC-TaR-00317

Ensembl Protein ID

ENSTRUP00000016171.1

UniProt Accession

H2SUT3; H2SUT3_TAKRU

Protein Name

Uncharacterized protein

Gene Name

trip12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000006584.1	ENSTRUT00000016243.1	ENSTRUP00000016171.1
ENSTRUG00000006584.1	ENSTRUT00000016244.1	ENSTRUP00000016172.1
ENSTRUG00000006584.1	ENSTRUT00000016245.1	ENSTRUP00000016173.1
ENSTRUG00000006584.1	ENSTRUT00000016246.1	ENSTRUP00000016174.1
ENSTRUG00000006584.1	ENSTRUT00000016247.1	ENSTRUP00000016175.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.60e-97	327.0	1654	2033

Active Site

Position(s)	Description	Evidence
2000	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 6    kkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp......................ehlkl 70
           ++ le+++++E g++l G+t+ef+al+s+elq++dlgl++ +e   ++ + n++ + k                        +    
   Q: 1654 RAMLEIQYENEVGTGL-GPTQEFYALVSQELQRADLGLWRGEEVTLANPKGNQEGM-K-YmfstrglfavpfgrttkpahiaKIKMK 1737
           56899***********.**********************76666555554444332.2.135667888889**********999999 PP
   S: 71   FeflGrllgkalqdgrlldlplsksfyklllgkklsl..edleevdpelykslkeikenaes......................... 130
           F+flG+l++ka++d rlldlpl  +fyk +l++++s+  +dl ++dp ++ks++ +++   +                         
   Q: 1738 FRFLGKLMAKAIMDFRLLDLPLGLPFYKWMLRHEMSVssHDLVNIDPGVAKSIQHLEDIIRQkkmleqdrsqtretlqqaleslnmn 1824
           *********************************766555******************998334455556666677775444444444 PP
   S: 131  ..dieelgldltfsvseei.....lgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFt 210
             ++e+            +     l+   + eLk gG++ipVt+ N+eeY +lvv ++l+eg+ +q+e+freGf++v+pl++l++F 
   Q: 1825 gcSVED------------LgldftLPGFPNIELKKGGKDIPVTIYNLEEYLRLVVYWTLNEGVSRQFESFREGFESVFPLHHLQYFY 1899
           444444............34455578999********************************************************** PP
   S: 211  eeelellicGe..eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirk.... 291
           +eele+l+cG+  e++dv++l + ++ ++gyt+ds+a+++++ev+++f++e+++ fLqFvTgs+rlP+gGf++l+p l+++rk    
   Q: 1900 PEELEQLLCGSksETWDVKTLMECCRPDHGYTHDSRAVRFLFEVMSGFDAEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKtfes 1986
           **********98889***********************************************************************9 PP
   S: 292  .dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFels 336
            ++ dd lPs++TC+nyLkLP+Yss e+++ekLl+A +e+ ++F+ls
   Q: 1987 tENPDDFLPSVMTCVNYLKLPDYSSIETMREKLLIAAREGqQSFHLS 2033
           88888***************************************985 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MSNRPNSNPG GSLRRSQRNT AATQPQDHTI TGRLQSEQVK HKTNSPPEGR RPNSKASKAT 60
ASSATGQSRG HSSKRSSLAL SIASFALQDE PEAAGTSIED RLGHQSKAET ARALKRSEAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCAACC GGCCTAATTC CAATCCAGGG GGGTCACTGC GCCGTTCACA GAGGAACACT 60
GCTGCGACCC AGCCACAAGA CCACACAATC ACCGGAAGGT AAGGCCACCC CGAGAGCCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000569--HECT_dom
IPR004170--WWE-dom

PROSITE

PS50237--HECT
PS50918--WWE

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000750	Aegilops tauschii	38.23	2.00e-127	451.00
IUUC-Aml-001502	Ailuropoda melanoleuca	82.31	0.00e+00	3061.00
IUUC-Atr-002821	Amborella trichopoda	37.59	7.00e-119	422.00
IUUC-Apl-003531	Anas platyrhynchos	81.23	0.00e+00	2988.00
IUUC-Aly-005962	Arabidopsis lyrata	38.59	7.00e-116	412.00
IUUC-Ath-006636	Arabidopsis thaliana	44.36	2.00e-116	414.00
IUUC-Ago-007875	Ashbya gossypii	36.65	1.00e-82	301.00
IUUC-Acl-008242	Aspergillus clavatus	36.87	8.00e-118	419.00
IUUC-Afl-008736	Aspergillus flavus	41.02	3.00e-116	414.00
IUUC-Afu-008812	Aspergillus fumigatus	37.18	4.00e-120	426.00
IUUC-Ani-009407	Aspergillus nidulans	38.75	9.00e-116	412.00
IUUC-Ang-009763	Aspergillus niger	40.55	1.00e-110	395.00
IUUC-Aor-009941	Aspergillus oryzae	31.72	3.00e-118	420.00
IUUC-Ate-010459	Aspergillus terreus	38.72	1.00e-91	332.00
IUUC-Ame-011761	Astyanax mexicanus	90.71	0.00e+00	3034.00
IUUC-Bgr-012265	Blumeria graminis	35.71	2.00e-105	377.00
IUUC-Bta-013070	Bos taurus	80.40	0.00e+00	3022.00
IUUC-Bci-013890	Botrytis cinerea	40.52	8.00e-105	376.00
IUUC-Bdi-014046	Brachypodium distachyon	37.75	2.00e-124	441.00
IUUC-Bol-015942	Brassica oleracea	43.46	6.00e-115	409.00
IUUC-Bra-016849	Brassica rapa	43.46	2.00e-114	408.00
IUUC-Cja-019046	Callithrix jacchus	87.56	0.00e+00	2968.00
IUUC-Cfa-020521	Canis familiaris	80.84	0.00e+00	2962.00
IUUC-Cpo-021639	Cavia porcellus	79.09	0.00e+00	2971.00
IUUC-Cre-022767	Chlamydomonas reinhardtii	40.08	1.00e-90	326.00
IUUC-Csa-023231	Chlorocebus sabaeus	86.46	0.00e+00	2958.00
IUUC-Cho-024380	Choloepus hoffmanni	74.16	0.00e+00	2762.00
IUUC-Cin-025482	Ciona intestinalis	49.72	2.00e-156	545.00
IUUC-Csv-026121	Ciona savignyi	48.42	0.00e+00	1537.00
IUUC-Cgl-026716	Colletotrichum gloeosporioides	35.74	1.00e-110	395.00
IUUC-Cne-026857	Cryptococcus neoformans	40.49	5.00e-95	343.00
IUUC-Cme-027226	Cyanidioschyzon merolae	34.72	2.00e-73	271.00
IUUC-Dre-028174	Danio rerio	90.58	0.00e+00	3089.00
IUUC-Dor-030939	Dipodomys ordii	77.93	0.00e+00	2495.00
IUUC-Dse-031444	Dothistroma septosporum	40.12	3.00e-108	387.00
IUUC-Dme-032162	Drosophila melanogaster	56.26	0.00e+00	667.00
IUUC-Ete-032345	Echinops telfairi	80.31	0.00e+00	2041.00
IUUC-Eca-033229	Equus caballus	82.06	0.00e+00	3018.00
IUUC-Eeu-035205	Erinaceus europaeus	72.32	0.00e+00	2576.00
IUUC-Fca-036444	Felis catus	80.78	0.00e+00	3048.00
IUUC-Fal-037131	Ficedula albicollis	81.18	0.00e+00	3066.00
IUUC-Fox-038035	Fusarium oxysporum	36.12	2.00e-109	389.00
IUUC-Fso-038320	Fusarium solani	35.41	8.00e-109	389.00
IUUC-Gmo-039497	Gadus morhua	88.14	0.00e+00	3316.00
IUUC-Ggr-040057	Gaeumannomyces graminis	35.15	6.00e-106	379.00
IUUC-Gga-041021	Gallus gallus	81.35	0.00e+00	3069.00
IUUC-Gac-042474	Gasterosteus aculeatus	90.96	0.00e+00	3378.00
IUUC-Gma-043060	Glycine max	38.07	2.00e-120	428.00
IUUC-Ggo-044855	Gorilla gorilla	87.50	0.00e+00	2966.00
IUUC-Hsa-046147	Homo sapiens	87.32	0.00e+00	2975.00
IUUC-Hvu-047775	Hordeum vulgare	38.39	7.00e-126	446.00
IUUC-Itr-048131	Ictidomys tridecemlineatus	86.14	0.00e+00	2946.00
IUUC-Kpa-049098	Komagataella pastoris	37.43	4.00e-84	307.00
IUUC-Lch-049818	Latimeria chalumnae	85.03	0.00e+00	2862.00
IUUC-Lpe-051017	Leersia perrieri	37.04	1.00e-118	422.00
IUUC-Loc-051777	Lepisosteus oculatus	85.84	0.00e+00	3273.00
IUUC-Lma-052990	Leptosphaeria maculans	37.08	4.00e-114	407.00
IUUC-Laf-053727	Loxodonta africana	81.77	0.00e+00	3044.00
IUUC-Mcc-055799	Macaca mulatta	86.57	0.00e+00	2887.00
IUUC-Meu-056065	Macropus eugenii	81.82	0.00e+00	1885.00
IUUC-Mor-057054	Magnaporthe oryzae	38.45	5.00e-105	376.00
IUUC-Mpo-057417	Magnaporthe poae	39.51	1.00e-106	382.00
IUUC-Mtr-057849	Medicago truncatula	36.92	3.00e-113	404.00
IUUC-Mla-058870	Melampsora laricipopulina	42.37	3.00e-108	387.00
IUUC-Mga-059580	Meleagris gallopavo	82.09	0.00e+00	2642.00
IUUC-Mvi-060507	Microbotryum violaceum	40.74	3.00e-116	414.00
IUUC-Mmr-060816	Microcebus murinus	80.84	0.00e+00	3061.00
IUUC-Mdo-062866	Monodelphis domestica	79.08	0.00e+00	2845.00
IUUC-Mmu-063906	Mus musculus	79.72	0.00e+00	2996.00
IUUC-Mac-064675	Musa acuminata	38.01	7.00e-111	394.00
IUUC-Mpu-066199	Mustela putorius furo	78.79	0.00e+00	2931.00
IUUC-Mlu-067110	Myotis lucifugus	79.88	0.00e+00	2970.00
IUUC-Nfi-068482	Neosartorya fischeri	37.03	4.00e-119	423.00
IUUC-Ncr-068906	Neurospora crassa	38.29	5.00e-106	380.00
IUUC-Nle-069410	Nomascus leucogenys	87.37	0.00e+00	2956.00
IUUC-Opr-070401	Ochotona princeps	72.98	0.00e+00	2550.00
IUUC-Ont-072100	Oreochromis niloticus	91.90	0.00e+00	3441.00
IUUC-Oan-073121	Ornithorhynchus anatinus	81.31	0.00e+00	3101.00
IUUC-Ocu-074623	Oryctolagus cuniculus	86.22	0.00e+00	2881.00
IUUC-Oba-075380	Oryza barthii	36.07	2.00e-113	403.00
IUUC-Obr-076915	Oryza brachyantha	36.34	9.00e-119	422.00
IUUC-Ogl-077055	Oryza glaberrima	37.16	2.00e-118	421.00
IUUC-Ogu-078892	Oryza glumaepatula	40.44	5.00e-113	402.00
IUUC-Oin-079256	Oryza indica	36.85	3.00e-117	417.00
IUUC-Olo-080343	Oryza longistaminata	36.99	6.00e-117	416.00
IUUC-Ome-081422	Oryza meridionalis	36.99	6.00e-117	416.00
IUUC-Oni-083047	Oryza nivara	40.95	2.00e-114	407.00
IUUC-Opu-083641	Oryza punctata	40.22	6.00e-110	392.00
IUUC-Oru-084439	Oryza rufipogon	40.77	4.00e-113	403.00
IUUC-Osa-085972	Oryza sativa	37.16	2.00e-116	413.00
IUUC-Ola-087173	Oryzias latipes	87.25	0.00e+00	3284.00
IUUC-Olu-087871	Ostreococcus lucimarinus	36.31	4.00e-89	322.00
IUUC-Oga-087908	Otolemur garnettii	81.48	0.00e+00	3068.00
IUUC-Oar-090277	Ovis aries	79.36	0.00e+00	3003.00
IUUC-Ptr-091543	Pan troglodytes	87.32	0.00e+00	2977.00
IUUC-Pan-092243	Papio anubis	86.51	0.00e+00	2886.00
IUUC-Psi-093150	Pelodiscus sinensis	82.87	0.00e+00	3135.00
IUUC-Pno-094891	Phaeosphaeria nodorum	41.51	8.00e-116	412.00
IUUC-Ppa-095181	Physcomitrella patens	41.75	6.00e-106	378.00
IUUC-Pfo-096267	Poecilia formosa	89.82	0.00e+00	3301.00
IUUC-Pab-098072	Pongo abelii	87.65	0.00e+00	2963.00
IUUC-Pop-099190	Populus trichocarpa	37.29	8.00e-117	416.00
IUUC-Pca-100311	Procavia capensis	75.60	0.00e+00	2744.00
IUUC-Ppe-101284	Prunus persica	37.18	1.00e-116	415.00
IUUC-Pva-102215	Pteropus vampyrus	77.00	0.00e+00	1019.00
IUUC-Pgr-103694	Puccinia graminis	40.80	9.00e-107	382.00
IUUC-Ptt-103916	Puccinia triticina	40.00	8.00e-103	369.00
IUUC-Pte-104346	Pyrenophora teres	41.12	9.00e-114	405.00
IUUC-Pyt-104508	Pyrenophora triticirepentis	41.12	3.00e-113	404.00
IUUC-Rno-105315	Rattus norvegicus	86.28	0.00e+00	2858.00
IUUC-Sce-106273	Saccharomyces cerevisiae	34.07	1.00e-69	259.00
IUUC-Sha-106835	Sarcophilus harrisii	80.35	0.00e+00	3115.00
IUUC-Sja-107943	Schizosaccharomyces japonicus	39.19	6.00e-98	352.00
IUUC-Spo-108081	Schizosaccharomyces pombe	40.37	1.00e-97	352.00
IUUC-Ssl-108560	Sclerotinia sclerotiorum	40.68	3.00e-108	387.00
IUUC-Smo-108776	Selaginella moellendorffii	43.47	4.00e-113	403.00
IUUC-Sit-109757	Setaria italica	37.73	6.00e-122	432.00
IUUC-Sly-111469	Solanum lycopersicum	38.71	2.00e-120	428.00
IUUC-Stu-112896	Solanum tuberosum	37.41	4.00e-105	375.00
IUUC-Sar-113224	Sorex araneus	70.62	0.00e+00	1512.00
IUUC-Sbi-114313	Sorghum bicolor	37.43	2.00e-123	438.00
IUUC-Sre-114993	Sporisorium reilianum	33.38	2.00e-101	365.00
IUUC-Ssc-115535	Sus scrofa	76.41	0.00e+00	2890.00
IUUC-Tgu-117493	Taeniopygia guttata	81.59	0.00e+00	2399.00
IUUC-Tsy-119373	Tarsius syrichta	80.84	0.00e+00	1632.00
IUUC-Tni-120049	Tetraodon nigroviridis	86.61	0.00e+00	948.00
IUUC-Tca-121779	Theobroma cacao	37.91	2.00e-114	408.00
IUUC-Tre-122195	Trichoderma reesei	36.42	1.00e-105	379.00
IUUC-Tvi-122650	Trichoderma virens	35.64	4.00e-106	380.00
IUUC-Tae-123580	Triticum aestivum	38.15	1.00e-125	444.00
IUUC-Tur-126295	Triticum urartu	38.39	4.00e-127	449.00
IUUC-Tme-126964	Tuber melanosporum	41.07	2.00e-107	385.00
IUUC-Tbe-128149	Tupaia belangeri	74.02	0.00e+00	1122.00
IUUC-Ttr-128165	Tursiops truncatus	85.05	0.00e+00	2753.00
IUUC-Uma-129365	Ustilago maydis	35.18	3.00e-88	321.00
IUUC-Vda-129725	Verticillium dahliae	41.08	6.00e-108	386.00
IUUC-Vpa-130678	Vicugna pacos	85.79	0.00e+00	2394.00
IUUC-Vvi-131147	Vitis vinifera	38.41	4.00e-120	426.00
IUUC-Xtr-132636	Xenopus tropicalis	78.72	0.00e+00	2929.00
IUUC-Xma-133458	Xiphophorus maculatus	89.92	0.00e+00	3353.00
IUUC-Yli-134481	Yarrowia lipolytica	38.45	2.00e-99	357.00
IUUC-Zma-135782	Zea mays	37.32	1.00e-117	419.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence