iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062834

Ensembl Protein ID

ENSMODP00000016389.3

UniProt Accession

F7EXM4; F7EXM4_MONDO

Protein Name

Uncharacterized protein

Gene Name

EML1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000013095.3	ENSMODT00000016691.3	ENSMODP00000016389.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.70e-19	67.9	572	602

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gHtd+ ++la  s+   ++++++D+ + +WD
   Q: 572  GHTDELWGLAIhSSkSQFLTCGHDKHVTLWD 602
           8**********966689************** PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MEDGFSSYSS LYDTSSLLQF CNDDSASAAS SMEVTDRIAS LEQRVQMQED DIQLLKSALA 60
DVVRRLNITE EQQAMLNRKG PTKDQNLTKK ASTGEADKHV SSAISARPLV QTLPLRTTVN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGACG GATTTTCTAG CTACAGCAGC CTCTATGACA CTTCTTCGCT GCTGCAGTTC 60
TGCAACGGTA AGGAGAGAAG ACCTGGGGAG AAGTGTGGGG GTGGTGGTGT TGGTGGTGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR002469--Peptidase_S9B_N
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0015630--C:microtubule cytoskeleton
GO:1990023--C:mitotic spindle midzone
GO:0097431--C:mitotic spindle pole
GO:0008017--F:microtubule binding
GO:0007420--P:brain development
GO:0002244--P:hematopoietic progenitor cell differentiation
GO:0007052--P:mitotic spindle organization
GO:0007405--P:neuroblast proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002077	Ailuropoda melanoleuca	86.96	0.00e+00	1450.00
IUUC-Apl-004179	Anas platyrhynchos	91.50	0.00e+00	1472.00
IUUC-Aca-004993	Anolis carolinensis	85.91	0.00e+00	1400.00
IUUC-Ame-011332	Astyanax mexicanus	74.94	0.00e+00	1306.00
IUUC-Bta-013419	Bos taurus	75.36	0.00e+00	1205.00
IUUC-Cel-018623	Caenorhabditis elegans	29.48	5.00e-83	302.00
IUUC-Cja-018976	Callithrix jacchus	88.97	0.00e+00	1464.00
IUUC-Cfa-021276	Canis familiaris	89.39	0.00e+00	1460.00
IUUC-Csa-023355	Chlorocebus sabaeus	88.85	0.00e+00	1448.00
IUUC-Cin-025784	Ciona intestinalis	54.77	0.00e+00	743.00
IUUC-Csv-026305	Ciona savignyi	47.30	0.00e+00	752.00
IUUC-Dre-028728	Danio rerio	77.78	0.00e+00	1335.00
IUUC-Dno-029055	Dasypus novemcinctus	86.33	0.00e+00	1469.00
IUUC-Dor-030628	Dipodomys ordii	88.32	0.00e+00	1440.00
IUUC-Dme-032093	Drosophila melanogaster	37.48	5.00e-122	432.00
IUUC-Ete-032845	Echinops telfairi	91.04	0.00e+00	796.00
IUUC-Eca-034266	Equus caballus	89.81	0.00e+00	1520.00
IUUC-Eeu-035302	Erinaceus europaeus	64.03	9.00e-153	533.00
IUUC-Fca-035446	Felis catus	90.07	0.00e+00	1444.00
IUUC-Fal-036734	Ficedula albicollis	88.06	0.00e+00	1466.00
IUUC-Gmo-038689	Gadus morhua	71.81	0.00e+00	1259.00
IUUC-Gga-040934	Gallus gallus	93.15	0.00e+00	1139.00
IUUC-Gac-042476	Gasterosteus aculeatus	73.10	0.00e+00	1260.00
IUUC-Ggo-044828	Gorilla gorilla	88.53	0.00e+00	1499.00
IUUC-Hsa-045664	Homo sapiens	89.25	0.00e+00	1519.00
IUUC-Lch-050508	Latimeria chalumnae	88.77	0.00e+00	1484.00
IUUC-Loc-052823	Lepisosteus oculatus	85.07	0.00e+00	1416.00
IUUC-Laf-054164	Loxodonta africana	85.23	0.00e+00	1366.00
IUUC-Mcc-055810	Macaca mulatta	88.74	0.00e+00	1463.00
IUUC-Mga-059405	Meleagris gallopavo	90.29	0.00e+00	1468.00
IUUC-Mmr-061144	Microcebus murinus	92.23	0.00e+00	1497.00
IUUC-Mmu-063955	Mus musculus	89.83	0.00e+00	1460.00
IUUC-Mpu-066240	Mustela putorius furo	89.34	0.00e+00	1421.00
IUUC-Mlu-067847	Myotis lucifugus	88.54	0.00e+00	1067.00
IUUC-Nle-069783	Nomascus leucogenys	88.27	0.00e+00	1480.00
IUUC-Opr-070409	Ochotona princeps	81.12	0.00e+00	1299.00
IUUC-Ont-072468	Oreochromis niloticus	77.36	0.00e+00	1323.00
IUUC-Oan-073315	Ornithorhynchus anatinus	90.73	0.00e+00	1460.00
IUUC-Ocu-074604	Oryctolagus cuniculus	90.40	0.00e+00	1230.00
IUUC-Ola-086734	Oryzias latipes	73.73	0.00e+00	1255.00
IUUC-Oga-089105	Otolemur garnettii	88.21	0.00e+00	1461.00
IUUC-Oar-090057	Ovis aries	90.41	0.00e+00	1491.00
IUUC-Ptr-091138	Pan troglodytes	89.02	0.00e+00	1515.00
IUUC-Pan-092691	Papio anubis	82.27	0.00e+00	1333.00
IUUC-Psi-093076	Pelodiscus sinensis	89.07	0.00e+00	1466.00
IUUC-Pma-094555	Petromyzon marinus	56.70	0.00e+00	822.00
IUUC-Pfo-096794	Poecilia formosa	71.28	0.00e+00	1214.00
IUUC-Pab-097787	Pongo abelii	88.63	0.00e+00	1501.00
IUUC-Pva-102676	Pteropus vampyrus	86.71	0.00e+00	1409.00
IUUC-Rno-105971	Rattus norvegicus	81.94	0.00e+00	1260.00
IUUC-Sha-107530	Sarcophilus harrisii	93.48	0.00e+00	1496.00
IUUC-Ssc-116169	Sus scrofa	77.89	0.00e+00	1001.00
IUUC-Tgu-117046	Taeniopygia guttata	91.30	0.00e+00	1450.00
IUUC-Tru-118596	Takifugu rubripes	72.36	0.00e+00	1249.00
IUUC-Tsy-119142	Tarsius syrichta	84.62	0.00e+00	1061.00
IUUC-Tni-120377	Tetraodon nigroviridis	74.41	0.00e+00	1269.00
IUUC-Tbe-127916	Tupaia belangeri	74.31	0.00e+00	956.00
IUUC-Ttr-129042	Tursiops truncatus	88.37	0.00e+00	1491.00
IUUC-Xtr-132117	Xenopus tropicalis	82.52	0.00e+00	1354.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence