iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062600

Ensembl Protein ID

ENSMODP00000034131.1

UniProt Accession

F7DJP0; F7DJP0_MONDO

Protein Name

Uncharacterized protein

Gene Name

PACSIN3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000019903.4	ENSMODT00000035717.1	ENSMODP00000034131.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.40e-13	48.8	367	421

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v++lydy +q+ deL++++G+ +l +  +e ++gW++g+   +g+ Gl P+n+ve 
   Q: 367  RVRALYDYAGQEADELSFRAGEELLKM-SDEDEQGWCQGQ-LQSGRIGLYPANYVEC 421
           689********************9999.999********7.99************86 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MAPEDDAAGE IPGGSFWEAG NYKRTVQRVE DGHRLCGDLV GCFQERARIE KAYAQQLADW 60
ARKWRGAVEK GPQYGTLEKA WHAFLTAAER LSALHLEVRD KLHGEDSDRV RAWQREAFHR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTCCGG AGGACGACGC GGCCGGGGAG ATCCCTGGGG GCAGTTTCTG GGAGGTGAGA 60
GATGGAGGGA TGGAGGAGTT TGGGGCGGCG GGGGGGCGCT GTCTGAATTC TCCCCCTTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR027267--AH/BAR-dom
IPR031160--F_BAR
IPR001060--FCH_dom
IPR028523--PACSIN3
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005768--C:endosome
GO:0070062--C:extracellular exosome
GO:0005886--C:plasma membrane
GO:0019855--F:calcium channel inhibitor activity
GO:0008289--F:lipid binding
GO:0051926--P:negative regulation of calcium ion transport
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0051044--P:positive regulation of membrane protein ectodomain proteolysis
GO:0030100--P:regulation of endocytosis

KEGG

mdo:100012158

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001906	Ailuropoda melanoleuca	87.09	4.00e-174	604.00
IUUC-Apl-003211	Anas platyrhynchos	64.63	0.00e+00	630.00
IUUC-Aca-004256	Anolis carolinensis	64.18	4.00e-178	617.00
IUUC-Ame-011049	Astyanax mexicanus	60.36	5.00e-154	537.00
IUUC-Bta-013322	Bos taurus	85.20	0.00e+00	727.00
IUUC-Cel-018168	Caenorhabditis elegans	31.96	7.00e-47	181.00
IUUC-Cja-018907	Callithrix jacchus	87.03	0.00e+00	755.00
IUUC-Cfa-021126	Canis familiaris	87.03	0.00e+00	749.00
IUUC-Cpo-021491	Cavia porcellus	87.03	0.00e+00	755.00
IUUC-Csa-023107	Chlorocebus sabaeus	88.44	0.00e+00	761.00
IUUC-Cin-025707	Ciona intestinalis	41.76	8.00e-97	347.00
IUUC-Csv-026244	Ciona savignyi	45.61	1.00e-48	186.00
IUUC-Dre-027933	Danio rerio	60.32	5.00e-149	520.00
IUUC-Dno-029002	Dasypus novemcinctus	86.56	0.00e+00	723.00
IUUC-Dor-030122	Dipodomys ordii	50.96	4.00e-123	434.00
IUUC-Dme-032120	Drosophila melanogaster	44.15	1.00e-77	283.00
IUUC-Eca-033824	Equus caballus	87.03	0.00e+00	757.00
IUUC-Eeu-035122	Erinaceus europaeus	79.04	5.00e-163	566.00
IUUC-Fca-036420	Felis catus	87.26	0.00e+00	777.00
IUUC-Fal-037277	Ficedula albicollis	64.77	0.00e+00	632.00
IUUC-Gmo-039681	Gadus morhua	51.49	4.00e-117	414.00
IUUC-Gga-040941	Gallus gallus	64.55	0.00e+00	627.00
IUUC-Gac-041374	Gasterosteus aculeatus	59.95	1.00e-140	492.00
IUUC-Ggo-045211	Gorilla gorilla	88.21	0.00e+00	760.00
IUUC-Hsa-046053	Homo sapiens	88.44	0.00e+00	761.00
IUUC-Itr-047939	Ictidomys tridecemlineatus	87.50	0.00e+00	760.00
IUUC-Lch-050070	Latimeria chalumnae	47.23	3.00e-120	425.00
IUUC-Loc-052808	Lepisosteus oculatus	62.64	4.00e-158	550.00
IUUC-Laf-054211	Loxodonta africana	86.56	0.00e+00	723.00
IUUC-Mcc-055044	Macaca mulatta	88.44	0.00e+00	761.00
IUUC-Mga-059216	Meleagris gallopavo	64.49	0.00e+00	629.00
IUUC-Mmr-061172	Microcebus murinus	87.97	0.00e+00	763.00
IUUC-Mmu-063218	Mus musculus	86.56	0.00e+00	749.00
IUUC-Mpu-066819	Mustela putorius furo	87.69	3.00e-175	608.00
IUUC-Mlu-067597	Myotis lucifugus	84.69	0.00e+00	759.00
IUUC-Nle-069195	Nomascus leucogenys	87.97	0.00e+00	757.00
IUUC-Opr-071050	Ochotona princeps	86.82	0.00e+00	743.00
IUUC-Ont-071612	Oreochromis niloticus	55.65	4.00e-144	504.00
IUUC-Oan-073256	Ornithorhynchus anatinus	87.32	0.00e+00	747.00
IUUC-Ocu-074653	Oryctolagus cuniculus	86.32	0.00e+00	721.00
IUUC-Ola-087188	Oryzias latipes	49.43	1.00e-103	370.00
IUUC-Oga-089040	Otolemur garnettii	86.56	0.00e+00	754.00
IUUC-Oar-089918	Ovis aries	87.32	0.00e+00	740.00
IUUC-Ptr-091307	Pan troglodytes	88.44	0.00e+00	761.00
IUUC-Pan-092512	Papio anubis	88.44	0.00e+00	761.00
IUUC-Psi-093704	Pelodiscus sinensis	49.79	2.00e-122	432.00
IUUC-Pfo-096881	Poecilia formosa	59.87	2.00e-154	538.00
IUUC-Pab-098620	Pongo abelii	88.44	0.00e+00	761.00
IUUC-Pva-102464	Pteropus vampyrus	85.61	0.00e+00	728.00
IUUC-Rno-106091	Rattus norvegicus	85.85	0.00e+00	745.00
IUUC-Sha-107474	Sarcophilus harrisii	93.63	0.00e+00	830.00
IUUC-Sar-113461	Sorex araneus	50.11	2.00e-119	422.00
IUUC-Ssc-116128	Sus scrofa	86.79	0.00e+00	755.00
IUUC-Tgu-117511	Taeniopygia guttata	61.89	5.00e-178	617.00
IUUC-Tru-118005	Takifugu rubripes	59.91	4.00e-141	494.00
IUUC-Tsy-118901	Tarsius syrichta	45.70	1.00e-70	260.00
IUUC-Tni-119851	Tetraodon nigroviridis	64.82	2.00e-142	498.00
IUUC-Ttr-129313	Tursiops truncatus	86.32	0.00e+00	764.00
IUUC-Vpa-130760	Vicugna pacos	87.98	8.00e-93	333.00
IUUC-Xtr-132697	Xenopus tropicalis	57.41	3.00e-142	498.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence