iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-061874

Ensembl Protein ID

ENSMODP00000001492.1

UniProt Accession

F7FWS4; F7FWS4_MONDO

Protein Name

Uncharacterized protein

Gene Name

FAF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000001243.3	ENSMODT00000001524.2	ENSMODP00000001492.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.00e-07	32.0	5	45
ULD/UDP/UFD/UBX	7.10e-20	71.5	569	646
ULD/UDP/UBQ/UBQ_Other	8.40e-10	38.6	111	170

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 1    sededkleqlve.MGF.dreealqaLraannnleaAveyLl 39
           +++e++l+ +++ +G+ + +ea++ L+++n++l aA++ ++
   Q: 5    MDREMILADFQAcTGIeNIDEAITLLEQNNWDLVAAINGVI 45
           689**********************************9875 PP

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfveyllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllve 80
           t++ ++l+iR+p+G++l+r+F +s +l+ +++fv+ ++++++d+F+L+s+fPrr++++ + +++l e +L+p+++l++e
   Q: 569  TEPVSKLRIRTPSGEFLERRFLASSQLRVVFDFVA-SKGFPWDEFKLLSTFPRRDVTQLDPNKSLLEVNLFPQETLFLE 646
           5669*******************************.****************************************986 PP

ULD/UDP/UBQ/UBQ_Other

   S: 12   eltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiL...eddktLadyglkdgstihll 70
           + ++ ++ s+tV+e+K+ +e +l ip   +++++kG      ed   L+ ++l+ ++ +++l
   Q: 111  NVDVVLEDSCTVGEIKQILENELQIP--VSKMLLKGWKTgdvEDSTVLKTLHLPKNNCLYVL 170
           5566678999****************..5589999777666699999999999998877776 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MASNMDREMI LADFQACTGI ENIDEAITLL EQNNWDLVAA INGVIPQENG ILQSEYGGET 60
GQGPAYGPAS QSAASASAPS SSAFRPVVPS RQIVERQPRM LDFRVEYRDR NVDVVLEDSC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTCGCTCCG CCCATCGCAG GCGACGCTTG ACAGGAGGTC GGTCACGTGG CAGCCGCAAA 60
GCGACGCTTT GCGACCCCAA TGACAGGCAA AATGTGCGAC AGCGGCGGCG CCGGCCAACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033043--FAF1_UBX
IPR012336--Thioredoxin-like_fold
IPR006577--UAS
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50033--UBX

Pfam

PF00789--UBX

SMART

SM00594--UAS
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0005635--C:nuclear envelope
GO:0048471--C:perinuclear region of cytoplasm
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0008219--P:cell death
GO:0007253--P:cytoplasmic sequestering of NF-kappaB
GO:1902043--P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:0031334--P:positive regulation of protein complex assembly
GO:0030155--P:regulation of cell adhesion
GO:0042176--P:regulation of protein catabolic process

KEGG

mdo:100021009

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002153	Ailuropoda melanoleuca	91.54	0.00e+00	1160.00
IUUC-Apl-004127	Anas platyrhynchos	92.46	0.00e+00	1158.00
IUUC-Aca-005188	Anolis carolinensis	90.42	0.00e+00	1121.00
IUUC-Ame-010696	Astyanax mexicanus	76.23	0.00e+00	862.00
IUUC-Bta-012965	Bos taurus	91.85	0.00e+00	1169.00
IUUC-Cel-018420	Caenorhabditis elegans	28.24	1.00e-28	121.00
IUUC-Cja-019128	Callithrix jacchus	92.04	0.00e+00	1169.00
IUUC-Cfa-021201	Canis familiaris	73.72	0.00e+00	895.00
IUUC-Cpo-021475	Cavia porcellus	92.11	0.00e+00	868.00
IUUC-Csa-024076	Chlorocebus sabaeus	91.85	0.00e+00	1167.00
IUUC-Cho-025067	Choloepus hoffmanni	79.08	0.00e+00	1023.00
IUUC-Cin-025663	Ciona intestinalis	43.22	1.00e-68	253.00
IUUC-Csv-025894	Ciona savignyi	34.17	6.00e-70	258.00
IUUC-Dre-027508	Danio rerio	74.22	0.00e+00	942.00
IUUC-Dno-029336	Dasypus novemcinctus	91.23	0.00e+00	1150.00
IUUC-Dor-030218	Dipodomys ordii	84.92	0.00e+00	1047.00
IUUC-Dme-031581	Drosophila melanogaster	36.44	5.00e-84	305.00
IUUC-Ete-032860	Echinops telfairi	71.01	0.00e+00	636.00
IUUC-Eca-034321	Equus caballus	92.90	0.00e+00	1003.00
IUUC-Eeu-034844	Erinaceus europaeus	69.27	3.00e-136	479.00
IUUC-Fca-036575	Felis catus	92.29	0.00e+00	689.00
IUUC-Fal-037128	Ficedula albicollis	92.15	0.00e+00	1180.00
IUUC-Gmo-038694	Gadus morhua	74.12	0.00e+00	903.00
IUUC-Gga-040826	Gallus gallus	91.85	0.00e+00	1187.00
IUUC-Gac-042125	Gasterosteus aculeatus	74.16	0.00e+00	967.00
IUUC-Ggo-045254	Gorilla gorilla	92.31	0.00e+00	1176.00
IUUC-Hsa-046722	Homo sapiens	92.15	0.00e+00	1174.00
IUUC-Itr-048149	Ictidomys tridecemlineatus	90.80	5.00e-96	342.00
IUUC-Lch-050312	Latimeria chalumnae	81.29	0.00e+00	684.00
IUUC-Loc-051990	Lepisosteus oculatus	80.64	0.00e+00	964.00
IUUC-Laf-054375	Loxodonta africana	92.57	0.00e+00	694.00
IUUC-Mcc-054627	Macaca mulatta	91.84	0.00e+00	1144.00
IUUC-Meu-056611	Macropus eugenii	79.01	7.00e-141	494.00
IUUC-Mga-059400	Meleagris gallopavo	89.69	0.00e+00	1162.00
IUUC-Mmr-060882	Microcebus murinus	91.08	0.00e+00	1137.00
IUUC-Mmu-063444	Mus musculus	90.77	0.00e+00	1159.00
IUUC-Mpu-065713	Mustela putorius furo	91.34	0.00e+00	1121.00
IUUC-Mlu-068122	Myotis lucifugus	89.72	0.00e+00	1114.00
IUUC-Nle-069025	Nomascus leucogenys	91.69	0.00e+00	1162.00
IUUC-Opr-071089	Ochotona princeps	81.08	0.00e+00	1049.00
IUUC-Ont-072421	Oreochromis niloticus	74.55	0.00e+00	957.00
IUUC-Oan-073092	Ornithorhynchus anatinus	89.92	0.00e+00	882.00
IUUC-Ola-086497	Oryzias latipes	74.96	0.00e+00	957.00
IUUC-Oga-088854	Otolemur garnettii	91.54	0.00e+00	1174.00
IUUC-Oar-090120	Ovis aries	91.85	0.00e+00	1150.00
IUUC-Ptr-091554	Pan troglodytes	92.31	0.00e+00	1176.00
IUUC-Pan-091985	Papio anubis	92.00	0.00e+00	1152.00
IUUC-Psi-093548	Pelodiscus sinensis	92.76	0.00e+00	1128.00
IUUC-Pma-094123	Petromyzon marinus	51.74	5.00e-52	196.00
IUUC-Pfo-096729	Poecilia formosa	73.89	0.00e+00	956.00
IUUC-Pab-097810	Pongo abelii	92.31	0.00e+00	1175.00
IUUC-Pca-101079	Procavia capensis	84.06	0.00e+00	852.00
IUUC-Pva-102534	Pteropus vampyrus	84.42	0.00e+00	886.00
IUUC-Rno-105127	Rattus norvegicus	89.90	0.00e+00	1046.00
IUUC-Sha-106667	Sarcophilus harrisii	98.91	0.00e+00	1103.00
IUUC-Sar-113424	Sorex araneus	78.65	6.00e-180	624.00
IUUC-Ssc-115974	Sus scrofa	91.97	0.00e+00	1117.00
IUUC-Tgu-116495	Taeniopygia guttata	92.15	0.00e+00	1181.00
IUUC-Tru-118727	Takifugu rubripes	72.60	0.00e+00	932.00
IUUC-Tsy-118906	Tarsius syrichta	86.15	0.00e+00	1049.00
IUUC-Tni-119717	Tetraodon nigroviridis	75.00	0.00e+00	945.00
IUUC-Tbe-127849	Tupaia belangeri	78.63	0.00e+00	692.00
IUUC-Ttr-128660	Tursiops truncatus	87.27	0.00e+00	1103.00
IUUC-Vpa-130359	Vicugna pacos	92.28	0.00e+00	1145.00
IUUC-Xtr-132212	Xenopus tropicalis	83.64	0.00e+00	713.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence