iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-021375

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02027790

Gene Name

USP50

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000005401.3	ENSCPOT00000005459.2	ENSCPOP00000004861.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.70e-89	298.3	40	354

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           Gl+NlgNtCYmN+vLQcL+++p+l++++ + ++  +l+     ++  e++++++ l++ +w ++   vsp+e+ +al+++++ f++  q
   Q: 40   GLRNLGNTCYMNAVLQCLASVPPLAQYFRSgQYVTALR-----KDCREVATAFAYLLTDMWLGDADCVSPEEFRAALGRLHPDFTKRTQ 123
           9*****************************44444444.....4567****************************************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           qDaqEfl ++l++l+e+l++     +++ ++e+  ++++   ++   +++s+i++lF+gql  +i+cl+c+n s r+e f+ lslp+p+
   Q: 124  QDAQEFLIYVLNALHEALSR-----YHQRSGEK--RSTQRCCSRGIASETSIITQLFEGQLNYSIMCLKCENCSYRNEVFTVLSLPIPS 205
           ******************44.....33333333..33445667889999**************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfct 266
           + e+   +lqdcL+ f+++++l+ +n+++c+ c+ kqe+  + +++k P+++i+hLkRf  + ++++++k+ + +++pl+ Ldl+p+ +
   Q: 206  EYEC---TLQDCLQCFFQQDTLTWNNQIHCSFCETKQETAVRASISKPPKTIIFHLKRF--DIQGQVKRKLRTDIHYPLTnLDLTPYIC 289
           ****...****************************************************..6677899********************* PP
   S: 267  speekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYk 336
              +k   + kY+L+avv+H G l++GHY+a ++n+  + W+ fdD++V+e++   v++   s aY+lfY 
   Q: 290  PVFRK---HPKYNLCAVVNHFGDLDGGHYTASCRNSVTQaWYSFDDTRVSEIPAPLVQT---SMAYLLFYS 354
           95544...89*************************98888*******************...********6 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

PSSEHSLSAH PHSTERTELP DPLPAREDPA RPPNPPGVAG LRNLGNTCYM NAVLQCLASV 60
PPLAQYFRSG QYVTALRKDC REVATAFAYL LTDMWLGDAD CVSPEEFRAA LGRLHPDFTK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCATCCTCAG AGCATTCTCT CTCTGCCCAT CCACACAGCA CGGAGCGCAC GGAGCTCCCT 60
GACCCGCTTC CCGCCCGCGA GGACCCCGCG CGGCCGCCAA ACCCACCGGG CGTGGCCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002089	Ailuropoda melanoleuca	78.98	4.00e-167	580.00
IUUC-Aca-005256	Anolis carolinensis	46.81	1.00e-87	316.00
IUUC-Bta-012753	Bos taurus	72.45	2.00e-156	544.00
IUUC-Cfa-020054	Canis familiaris	80.63	5.00e-152	530.00
IUUC-Csa-023902	Chlorocebus sabaeus	70.65	2.00e-83	301.00
IUUC-Cho-024755	Choloepus hoffmanni	64.69	2.00e-118	418.00
IUUC-Dor-030311	Dipodomys ordii	86.41	1.00e-95	342.00
IUUC-Ete-032570	Echinops telfairi	59.07	6.00e-94	337.00
IUUC-Eca-034343	Equus caballus	76.99	3.00e-164	570.00
IUUC-Eeu-034510	Erinaceus europaeus	78.10	2.00e-144	504.00
IUUC-Fca-035920	Felis catus	77.21	1.00e-166	578.00
IUUC-Fal-036903	Ficedula albicollis	57.28	3.00e-103	368.00
IUUC-Gac-042261	Gasterosteus aculeatus	41.37	4.00e-71	261.00
IUUC-Hsa-046665	Homo sapiens	73.15	1.00e-140	492.00
IUUC-Itr-048167	Ictidomys tridecemlineatus	80.68	2.00e-173	601.00
IUUC-Lch-049925	Latimeria chalumnae	53.94	1.00e-101	363.00
IUUC-Loc-051880	Lepisosteus oculatus	47.06	8.00e-79	288.00
IUUC-Laf-054494	Loxodonta africana	79.13	1.00e-167	582.00
IUUC-Mcc-055507	Macaca mulatta	79.27	9.00e-160	556.00
IUUC-Meu-055906	Macropus eugenii	68.22	1.00e-133	468.00
IUUC-Mmr-061564	Microcebus murinus	54.72	3.00e-84	304.00
IUUC-Mdo-061800	Monodelphis domestica	71.02	1.00e-154	538.00
IUUC-Mmu-063618	Mus musculus	77.18	1.00e-156	545.00
IUUC-Mpu-066699	Mustela putorius furo	77.56	8.00e-166	576.00
IUUC-Mlu-067672	Myotis lucifugus	77.68	2.00e-162	565.00
IUUC-Opr-070949	Ochotona princeps	76.35	3.00e-133	467.00
IUUC-Oan-073725	Ornithorhynchus anatinus	67.07	3.00e-131	461.00
IUUC-Ocu-074021	Oryctolagus cuniculus	81.48	6.00e-173	599.00
IUUC-Oga-088258	Otolemur garnettii	78.09	1.00e-152	531.00
IUUC-Oar-089881	Ovis aries	74.66	1.00e-164	572.00
IUUC-Ptr-090988	Pan troglodytes	73.10	2.00e-135	475.00
IUUC-Pan-091773	Papio anubis	75.20	8.00e-166	576.00
IUUC-Psi-093243	Pelodiscus sinensis	67.83	9.00e-128	449.00
IUUC-Pab-097713	Pongo abelii	74.47	1.00e-149	522.00
IUUC-Pca-100226	Procavia capensis	59.87	4.00e-111	394.00
IUUC-Pva-103172	Pteropus vampyrus	76.18	2.00e-147	514.00
IUUC-Rno-105950	Rattus norvegicus	77.10	7.00e-160	556.00
IUUC-Sha-107026	Sarcophilus harrisii	71.35	3.00e-155	541.00
IUUC-Ssc-116383	Sus scrofa	77.90	1.00e-167	582.00
IUUC-Tgu-116511	Taeniopygia guttata	54.63	5.00e-95	340.00
IUUC-Tbe-127808	Tupaia belangeri	63.97	4.00e-46	178.00
IUUC-Ttr-129046	Tursiops truncatus	73.75	3.00e-142	497.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence