iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034357

UUCD1 version

UUC-EqC-00879

Ensembl Protein ID

ENSECAP00000005740.1

UniProt Accession

F7DHM2; F7DHM2_HORSE

Protein Name

Uncharacterized protein

Gene Name

TRIM59

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000007762.1	ENSECAT00000007777.1	ENSECAP00000005740.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.60e-09	38.3	10	60
E3 activity/RING/U-box	2.90e-06	27.4	6	89

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefr..........CPlCr 46
           C+iC++ f+d p+vlpC H+f+++Cl+++     ++s++f+          CP Cr
   Q: 10   CPICYSIFED-PRVLPCSHTFCRNCLENV----LQASGNFYiwrplriplkCPNCR 60
           **********.***************999....667777766667777777****8 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggk...........tcPvtrqpl.....teedlvPnltlrrliqawcee 71
           +e+ CpI + +++dP vlp+ +t+ r+++e  l+ +g+           +cP +r+ +       e+l  n +lr++i+++ +e
   Q: 6    DELTCPICYSIFEDPRVLPCSHTFCRNCLENVLQASGNfyiwrplriplKCPNCRSIIeiaptGIESLPVNFALRAIIEKYQQE 89
           7899*****************************999999**********99999986533321456777799999999999776 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MHNFEDELTC PICYSIFEDP RVLPCSHTFC RNCLENVLQA SGNFYIWRPL RIPLKCPNCR 60
SIIEIAPTGI ESLPVNFALR AIIEKYQQED HPDIITCPEH YRQPLNVYCL LDKKLVCGHC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCACAATT TTGAGGATGA GTTAACGTGT CCTATTTGCT ACAGTATTTT TGAAGATCCT 60
CGTGTACTCC CATGCTCTCA TACATTTTGT AGAAACTGCT TAGAAAACGT TCTTCAGGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00184--RING

Gene Ontology

GO:0005813--C:centrosome
GO:0005929--C:cilium
GO:0005783--C:endoplasmic reticulum
GO:0016021--C:integral component of membrane
GO:0030992--C:intraciliary transport particle B
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0060271--P:cilium assembly
GO:0045087--P:innate immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046597--P:negative regulation of viral entry into host cell

KEGG

ecb:100049895

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002249	Ailuropoda melanoleuca	91.04	0.00e+00	742.00
IUUC-Apl-003996	Anas platyrhynchos	58.02	2.00e-123	435.00
IUUC-Aca-005141	Anolis carolinensis	57.53	8.00e-133	466.00
IUUC-Ame-011353	Astyanax mexicanus	51.43	5.00e-98	351.00
IUUC-Bta-013440	Bos taurus	92.82	0.00e+00	673.00
IUUC-Cfa-021168	Canis familiaris	92.00	0.00e+00	743.00
IUUC-Cpo-021702	Cavia porcellus	77.94	5.00e-180	623.00
IUUC-Csa-024141	Chlorocebus sabaeus	89.33	0.00e+00	669.00
IUUC-Dre-028408	Danio rerio	48.59	9.00e-91	327.00
IUUC-Dno-029180	Dasypus novemcinctus	89.83	0.00e+00	724.00
IUUC-Ete-033028	Echinops telfairi	87.30	7.00e-166	577.00
IUUC-Fca-036287	Felis catus	93.05	0.00e+00	750.00
IUUC-Gga-040739	Gallus gallus	57.39	6.00e-133	466.00
IUUC-Ggo-045307	Gorilla gorilla	87.34	0.00e+00	696.00
IUUC-Hsa-045690	Homo sapiens	88.09	0.00e+00	697.00
IUUC-Itr-048230	Ictidomys tridecemlineatus	92.06	0.00e+00	751.00
IUUC-Laf-054522	Loxodonta africana	87.06	0.00e+00	708.00
IUUC-Mcc-055145	Macaca mulatta	89.83	0.00e+00	712.00
IUUC-Meu-056214	Macropus eugenii	46.88	7.00e-61	227.00
IUUC-Mmr-061197	Microcebus murinus	93.55	0.00e+00	761.00
IUUC-Mdo-062631	Monodelphis domestica	60.85	8.00e-131	459.00
IUUC-Mmu-064217	Mus musculus	86.32	0.00e+00	692.00
IUUC-Mpu-065691	Mustela putorius furo	93.30	0.00e+00	757.00
IUUC-Mlu-067742	Myotis lucifugus	90.27	0.00e+00	702.00
IUUC-Nle-069722	Nomascus leucogenys	88.34	0.00e+00	728.00
IUUC-Oan-073382	Ornithorhynchus anatinus	59.70	4.00e-135	474.00
IUUC-Oar-089206	Ovis aries	91.32	0.00e+00	748.00
IUUC-Pan-092189	Papio anubis	90.07	0.00e+00	714.00
IUUC-Psi-093523	Pelodiscus sinensis	62.32	7.00e-144	503.00
IUUC-Pma-094162	Petromyzon marinus	32.61	4.00e-47	181.00
IUUC-Pfo-096032	Poecilia formosa	46.30	5.00e-88	318.00
IUUC-Pva-103089	Pteropus vampyrus	91.52	0.00e+00	708.00
IUUC-Pgr-103338	Puccinia graminis	38.71	2.00e-06	46.20
IUUC-Rno-105440	Rattus norvegicus	87.56	0.00e+00	699.00
IUUC-Ssc-115809	Sus scrofa	90.07	0.00e+00	707.00
IUUC-Tru-118402	Takifugu rubripes	44.07	7.00e-94	337.00
IUUC-Tni-119737	Tetraodon nigroviridis	44.05	8.00e-84	303.00
IUUC-Ttr-128921	Tursiops truncatus	91.00	0.00e+00	712.00
IUUC-Vpa-130397	Vicugna pacos	92.29	0.00e+00	746.00
IUUC-Xtr-132752	Xenopus tropicalis	48.05	4.00e-83	301.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence