iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092189

Ensembl Protein ID

ENSPANP00000008313.1

UniProt Accession

A0A096N730; A0A096N730_PAPAN

Genbank Protein ID

ENSPANP00000008313

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01073007

Gene Name

TRIM59

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000007299.1	ENSPANT00000006502.1	ENSPANP00000008313.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.00e-09	37.9	10	60
E3 activity/RING/U-box	2.80e-06	27.4	6	89

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefr..........CPlCr 46
           C+iC++ f+d p+vlpC H+f+++Cl+++     ++s++f+          CP Cr
   Q: 10   CPICYSIFED-PRVLPCSHTFCRNCLENI----LQASGNFYiwrplriplkCPNCR 60
           **********.***************999....567777766666666777****8 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggk...........tcPvtrqpl.....teedlvPnltlrrliqawcee 71
           ee+ CpI + +++dP vlp+ +t+ r+++e  l+ +g+           +cP +r+ +       e+l  n +lr++i+++ +e
   Q: 6    EELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNfyiwrplriplKCPNCRSIIeiaptGIESLPVNFALRAIIEKYQQE 89
           7999*****************************999999**********99999986533321456777799999999999776 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MHNFEEELTC PICYSIFEDP RVLPCSHTFC RNCLENILQA SGNFYIWRPL RIPLKCPNCR 60
SIIEIAPTGI ESLPVNFALR AIIEKYQQED HPDIVTCPEH YRQPLNVYCL LDKKLVCGHC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCACAATT TTGAGGAAGA GTTAACTTGT CCCATATGTT ACAGTATTTT TGAAGATCCT 60
CGTGTACTAC CATGCTCTCA TACATTTTGT AGAAATTGTT TGGAAAACAT TCTTCAGGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00184--RING

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046597--P:negative regulation of viral entry into host cell

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002249	Ailuropoda melanoleuca	90.05	0.00e+00	752.00
IUUC-Apl-003996	Anas platyrhynchos	58.77	4.00e-125	441.00
IUUC-Aca-005141	Anolis carolinensis	57.78	3.00e-134	471.00
IUUC-Ame-011353	Astyanax mexicanus	53.27	4.00e-101	361.00
IUUC-Bta-013440	Bos taurus	91.99	0.00e+00	686.00
IUUC-Cfa-021168	Canis familiaris	89.78	0.00e+00	746.00
IUUC-Cpo-021702	Cavia porcellus	76.37	7.00e-179	619.00
IUUC-Csa-024141	Chlorocebus sabaeus	98.76	0.00e+00	747.00
IUUC-Dre-028408	Danio rerio	47.88	3.00e-89	322.00
IUUC-Dno-029180	Dasypus novemcinctus	89.33	0.00e+00	735.00
IUUC-Ete-033028	Echinops telfairi	88.25	2.00e-168	586.00
IUUC-Eca-034357	Equus caballus	90.07	0.00e+00	722.00
IUUC-Fca-036287	Felis catus	90.82	0.00e+00	753.00
IUUC-Gga-040739	Gallus gallus	58.13	7.00e-137	480.00
IUUC-Ggo-045307	Gorilla gorilla	94.54	0.00e+00	754.00
IUUC-Hsa-045690	Homo sapiens	94.79	0.00e+00	755.00
IUUC-Itr-048230	Ictidomys tridecemlineatus	91.56	0.00e+00	763.00
IUUC-Laf-054522	Loxodonta africana	86.32	0.00e+00	718.00
IUUC-Mcc-055145	Macaca mulatta	99.75	0.00e+00	791.00
IUUC-Meu-056214	Macropus eugenii	48.07	4.00e-62	231.00
IUUC-Mmr-061197	Microcebus murinus	92.80	0.00e+00	772.00
IUUC-Mdo-062631	Monodelphis domestica	60.49	2.00e-136	478.00
IUUC-Mmu-064217	Mus musculus	85.32	0.00e+00	685.00
IUUC-Mpu-065691	Mustela putorius furo	91.81	0.00e+00	763.00
IUUC-Mlu-067742	Myotis lucifugus	87.28	0.00e+00	695.00
IUUC-Nle-069722	Nomascus leucogenys	95.29	0.00e+00	788.00
IUUC-Oan-073382	Ornithorhynchus anatinus	61.29	1.00e-137	482.00
IUUC-Oar-089206	Ovis aries	89.83	0.00e+00	747.00
IUUC-Psi-093523	Pelodiscus sinensis	63.79	4.00e-146	511.00
IUUC-Pma-094162	Petromyzon marinus	33.64	2.00e-47	182.00
IUUC-Pfo-096032	Poecilia formosa	47.88	7.00e-89	320.00
IUUC-Pva-103089	Pteropus vampyrus	89.28	0.00e+00	714.00
IUUC-Pgr-103338	Puccinia graminis	36.23	1.00e-06	47.00
IUUC-Rno-105440	Rattus norvegicus	86.07	0.00e+00	691.00
IUUC-Ssc-115809	Sus scrofa	88.83	0.00e+00	710.00
IUUC-Tru-118402	Takifugu rubripes	44.35	1.00e-94	339.00
IUUC-Tni-119737	Tetraodon nigroviridis	45.13	4.00e-85	307.00
IUUC-Ttr-128921	Tursiops truncatus	89.78	0.00e+00	720.00
IUUC-Vpa-130397	Vicugna pacos	90.55	0.00e+00	754.00
IUUC-Xtr-132752	Xenopus tropicalis	43.51	6.00e-86	310.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence