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Tag Content
UUCD2 ID IUUC-Xtr-131892
UUCD1 version UUC-XeT-01078
Ensembl Protein ID ENSXETP00000021444.3
UniProt Accession F6TAM3; F6TAM3_XENTR
Genbank Protein ID ENSXETP00000021444
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID AAMC01035294
Gene Name usp3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSXETG00000009728.3 ENSXETT00000021444.3 ENSXETP00000021444.3
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 2.40e-84 283.6 180 518
UBD/ZnF/ZnF_UBP 2.90e-26 91.6 26 105
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 14   SvLQcLsnipelrellle...........kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqD 91
           S++  + ni+++ ++++e             +++ + +++ + + +l+++++k + +lw+++++a+sp++l+ +++k+ ++f+gy+qqD
   Q: 180  SLIKYINNIQQFCCYFKElpavelrngktAGRRTYHTRSQGDVNVSLVEEFRKTLCALWQGNQTAFSPESLFYVVWKIMPNFRGYQQQD 268
           77888899**********887777666654444444555577778******************************************** PP
   S: 92   aqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgke 180
           a+Ef+++lld+l+ el+ e + + ++  +++++++s  +++   +  +++++ +F+g l++++ cl c+++s +++pfldlsl++p++ 
   Q: 269  AHEFMRYLLDHLHLELQGEFDGSSHSVLSQANCSRSA-SNKCCINGASTVVTSVFGGVLQNEVNCLICGTESRKFDPFLDLSLDIPSQF 356
           ****************765555555554444444444.4677889999**************************************655 PP
   S: 181  etkke.........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.L 259
            +k           +l+dcL+sft  eel++ + y c kckkkq+++kk++++klP+vL+lhLkRf+++   + r+k++++v+fpl+ L
   Q: 357  RNKRCknqengptcTLRDCLRSFTDLEELDETELYTCLKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTA--YLRNKVDTYVDFPLRgL 443
           33322566789999****************************************************7755..799************** PP
   S: 260  dlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
           d+++f+ +pe+   e++ Y+L avvvH+G +++sGHY+ay+ + kg+W++f+Ds+Vt ++ee+v +   ++aY+lfY +
   Q: 444  DMKSFLLEPENIGPESCLYDLAAVVVHHGsGVGSGHYTAYATH-KGRWFHFNDSTVTLTEEETVAK---AKAYILFYVE 518
           *******************************************.**********************...********76 PP
   

   UBD/ZnF/ZnF_UBP
   S: 1    kkcsvcdktenlWlcLtcgsvgCGRyvegHalkHyeetqhpl..................vlslstlsvycYacddyvhr 62
           ++csvc++++++W+cLtc+sv+CGRyv+gHa+kHye++q pl                  ++++s++s+ycY+cdd+v++
   Q: 26   WCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQAPLnchkrqektdkdrmqhtvCMDCSSYSTYCYRCDDFVVN 105
           9*****************************************************************************85 PP
   
Organism Xenopus tropicalis
Protein Sequence
(Fasta)
MECPHLTTSV CMPDAAVFPN GCPSSWCCSV CRSNKSPWVC LTCSSVHCGR YVNGHAKKHY 60
EDAQAPLNCH KRQEKTDKDR MQHTVCMDCS SYSTYCYRCD DFVVNDTKLC LVQKVREHLQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Xtr-131892|DUB,USP;UBD,ZnF_UBP|Xenopus tropicalis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGAGTGCC CGCACCTGAC CACCAGTGTT TGTATGTCCC GGACGCCGCC GTTTTTCCCA 60
ACGGCTGTCC TTCCTCATGG TGTTGCAGCG GTGAGTCTGG CTCCTCCTCC CCGAACTTTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Xtr-131892|DUB,USP;UBD,ZnF_UBP|Xenopus tropicalis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF00443--UCH
PF02148--zf-UBP
SMART

SM00290--ZnF_UBP
Gene Ontology

GO:0005634--C:nucleus
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016578--P:histone deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001537 Ailuropoda melanoleuca 82.80 0.00e+00 801.00
IUUC-Apl-003358 Anas platyrhynchos 83.17 0.00e+00 764.00
IUUC-Aca-004454 Anolis carolinensis 80.19 0.00e+00 712.00
IUUC-Ame-011544 Astyanax mexicanus 70.92 0.00e+00 663.00
IUUC-Bta-012738 Bos taurus 82.83 0.00e+00 781.00
IUUC-Cja-018893 Callithrix jacchus 82.61 0.00e+00 791.00
IUUC-Cfa-020607 Canis familiaris 83.18 0.00e+00 787.00
IUUC-Cpo-021828 Cavia porcellus 82.61 0.00e+00 777.00
IUUC-Csa-023884 Chlorocebus sabaeus 83.10 0.00e+00 647.00
IUUC-Cho-024863 Choloepus hoffmanni 78.26 0.00e+00 720.00
IUUC-Dre-028452 Danio rerio 69.74 0.00e+00 680.00
IUUC-Dno-029531 Dasypus novemcinctus 83.37 0.00e+00 738.00
IUUC-Dor-030913 Dipodomys ordii 73.47 2.00e-144 505.00
IUUC-Ete-032611 Echinops telfairi 78.64 0.00e+00 736.00
IUUC-Eca-033622 Equus caballus 83.37 0.00e+00 736.00
IUUC-Eeu-035268 Erinaceus europaeus 78.92 0.00e+00 667.00
IUUC-Fca-035801 Felis catus 83.57 0.00e+00 763.00
IUUC-Fal-036749 Ficedula albicollis 83.40 0.00e+00 737.00
IUUC-Gmo-039598 Gadus morhua 70.33 0.00e+00 697.00
IUUC-Gga-040883 Gallus gallus 83.37 0.00e+00 738.00
IUUC-Gac-042235 Gasterosteus aculeatus 69.38 0.00e+00 665.00
IUUC-Ggo-044767 Gorilla gorilla 78.20 0.00e+00 695.00
IUUC-Hsa-046581 Homo sapiens 82.80 0.00e+00 811.00
IUUC-Itr-047898 Ictidomys tridecemlineatus 83.36 0.00e+00 787.00
IUUC-Lch-049732 Latimeria chalumnae 81.59 0.00e+00 816.00
IUUC-Loc-052371 Lepisosteus oculatus 79.43 0.00e+00 796.00
IUUC-Laf-054565 Loxodonta africana 83.18 0.00e+00 784.00
IUUC-Mcc-055522 Macaca mulatta 83.36 0.00e+00 816.00
IUUC-Meu-056754 Macropus eugenii 72.99 5.00e-146 510.00
IUUC-Mga-060095 Meleagris gallopavo 80.06 8.00e-155 539.00
IUUC-Mmr-060839 Microcebus murinus 83.18 0.00e+00 788.00
IUUC-Mdo-062339 Monodelphis domestica 84.62 0.00e+00 647.00
IUUC-Mmu-063638 Mus musculus 82.80 0.00e+00 763.00
IUUC-Mpu-066647 Mustela putorius furo 83.48 0.00e+00 641.00
IUUC-Mlu-067921 Myotis lucifugus 82.57 0.00e+00 755.00
IUUC-Nle-069752 Nomascus leucogenys 82.99 0.00e+00 813.00
IUUC-Opr-070636 Ochotona princeps 73.49 2.00e-175 608.00
IUUC-Ont-071638 Oreochromis niloticus 71.10 0.00e+00 639.00
IUUC-Oan-073417 Ornithorhynchus anatinus 77.88 0.00e+00 752.00
IUUC-Ocu-074620 Oryctolagus cuniculus 81.85 0.00e+00 778.00
IUUC-Ola-087281 Oryzias latipes 70.98 2.00e-160 558.00
IUUC-Olu-087697 Ostreococcus lucimarinus 40.00 3.00e-47 181.00
IUUC-Oga-088448 Otolemur garnettii 82.42 0.00e+00 808.00
IUUC-Oar-090132 Ovis aries 82.80 0.00e+00 785.00
IUUC-Ptr-090696 Pan troglodytes 83.20 0.00e+00 764.00
IUUC-Pan-092124 Papio anubis 83.18 0.00e+00 813.00
IUUC-Psi-093801 Pelodiscus sinensis 83.94 0.00e+00 642.00
IUUC-Pma-094300 Petromyzon marinus 71.86 2.00e-96 345.00
IUUC-Pfo-096330 Poecilia formosa 72.66 0.00e+00 717.00
IUUC-Pab-098191 Pongo abelii 83.18 0.00e+00 815.00
IUUC-Pca-100341 Procavia capensis 80.46 5.00e-173 600.00
IUUC-Pva-103177 Pteropus vampyrus 83.18 0.00e+00 782.00
IUUC-Rno-105048 Rattus norvegicus 80.91 0.00e+00 749.00
IUUC-Sha-107429 Sarcophilus harrisii 83.60 0.00e+00 743.00
IUUC-Sar-113024 Sorex araneus 81.80 0.00e+00 685.00
IUUC-Ssc-115749 Sus scrofa 78.12 2.00e-123 434.00
IUUC-Tgu-117277 Taeniopygia guttata 83.57 0.00e+00 764.00
IUUC-Tru-117844 Takifugu rubripes 71.40 0.00e+00 705.00
IUUC-Tsy-119456 Tarsius syrichta 80.92 0.00e+00 728.00
IUUC-Tni-120251 Tetraodon nigroviridis 68.70 0.00e+00 721.00
IUUC-Tme-126976 Tuber melanosporum 34.04 2.00e-41 163.00
IUUC-Tbe-127423 Tupaia belangeri 80.91 0.00e+00 753.00
IUUC-Ttr-128401 Tursiops truncatus 76.71 0.00e+00 652.00
IUUC-Vpa-130549 Vicugna pacos 70.55 2.00e-130 458.00
Created Date 25-Jun-2017

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