iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037123

Ensembl Protein ID

ENSFALP00000008100.1

UniProt Accession

U3JZ96; U3JZ96_FICAL

Genbank Protein ID

ENSFALP00000008100

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01010269

Gene Name

HECTD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000007748.1	ENSFALT00000008133.1	ENSFALP00000008100.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	6.30e-89	298.3	417	760

Active Site

Position(s)	Description	Evidence
728	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           k+dlkk+l+v+fvgE+gld+gG+t+e++ ll++++++pd+g+f+y+++++++++ + +      ++ + F+++G l+g+a++++  ld+
   Q: 417  KADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSQCHWFSSFKC-----DNYSEFRLVGALMGLAVYNSITLDI 500
           789***************************************************87766.....789********************** PP
   S: 91   plsksfyklllgkk..............lsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           ++++++yk+ll+ +              ++l+dl +++pel++ l e++++ e ++ee  +  tf+v +e++g +k+++Lkp+G++ipV
   Q: 501  RFPPCCYKKLLSPPivpcdhntlvgicgVTLDDLFQIMPELAHGLSELLSY-EGNVEED-FYSTFQVFQEEFGVIKSYNLKPNGDKIPV 587
           ************9555566666666666**********************9.6788885.***************************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevle 254
           tn N++eYv+l+v++ l+++i +q++af+ Gf++v+    l l+++ee+e+l+cG++e+d+++l++ t+y+ gy++++ +i++ + ++ 
   Q: 588  TNRNRKEYVQLYVDFLLNRSIYKQFAAFYYGFHSVCASYALLLLRPEEVEILVCGSPELDMSALQRSTQYE-GYQKTDLTIRFIIIFIL 675
           **********************************************************************5.5********9999999* PP
   S: 255  efsseerkafLq.....FvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
            f +   + fL       ++g +r+P+gG+a+l+   f i+k ++s+++lP ++TCfn+L+LP+Y++k++lk+kL++ i++++gF+l+
   Q: 676  FFYNVALQHFLLplpsiDTSGIDRVPVGGMADLN---FKISKsETSTNWLPVAHTCFNQLCLPPYKNKKELKQKLIIGISNAEGFGLE 760
           ***********988887799**************...9999967777**************************************985 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

EKQKEKETEG KILPPIPSAS TAAAGGLEEG AKNQFSTFSN FITTINQKKE GIGNRNSPTQ 60
LVIPNIKNGR DLPPLCLDVR QKQRMSIDTL PQELKAPFPP EPSLPIRTKT VKDFQDDMEK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAAAACAAA AAGAAAAGGA GACGGAGGGA AAGATACTGC CGCCCATCCC GTCGGCGTCC 60
ACCGCGGCTG CCGGGGTAGG TCCCGTCAGC GCCCGGGCAG CCGCCCGCGG GCCCGCCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	82.81	0.00e+00	1254.00
IUUC-Apl-003589	Anas platyrhynchos	93.48	0.00e+00	1390.00
IUUC-Aca-004350	Anolis carolinensis	80.19	0.00e+00	1197.00
IUUC-Acl-008288	Aspergillus clavatus	33.66	1.00e-83	305.00
IUUC-Afl-008402	Aspergillus flavus	32.28	8.00e-77	281.00
IUUC-Ang-009791	Aspergillus niger	33.06	2.00e-77	284.00
IUUC-Aor-009921	Aspergillus oryzae	32.12	4.00e-76	279.00
IUUC-Ate-010295	Aspergillus terreus	33.44	3.00e-86	313.00
IUUC-Ame-010660	Astyanax mexicanus	76.32	5.00e-137	479.00
IUUC-Bta-012945	Bos taurus	81.48	0.00e+00	1223.00
IUUC-Cja-019263	Callithrix jacchus	80.24	0.00e+00	1201.00
IUUC-Cfa-020486	Canis familiaris	85.23	0.00e+00	1138.00
IUUC-Cpo-021755	Cavia porcellus	81.79	0.00e+00	1244.00
IUUC-Csa-023814	Chlorocebus sabaeus	80.45	0.00e+00	1140.00
IUUC-Cho-024980	Choloepus hoffmanni	66.85	0.00e+00	954.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	40.35	7.00e-84	305.00
IUUC-Dre-028551	Danio rerio	72.58	0.00e+00	1092.00
IUUC-Dno-029497	Dasypus novemcinctus	81.56	0.00e+00	1112.00
IUUC-Dor-030867	Dipodomys ordii	70.44	0.00e+00	1001.00
IUUC-Dse-031239	Dothistroma septosporum	30.32	6.00e-78	286.00
IUUC-Ete-032902	Echinops telfairi	68.86	0.00e+00	1009.00
IUUC-Eca-033678	Equus caballus	82.04	0.00e+00	1225.00
IUUC-Eeu-035262	Erinaceus europaeus	68.74	0.00e+00	915.00
IUUC-Fca-035590	Felis catus	82.86	0.00e+00	1254.00
IUUC-Fso-038388	Fusarium solani	39.57	6.00e-90	325.00
IUUC-Gmo-039553	Gadus morhua	64.24	0.00e+00	809.00
IUUC-Ggr-040110	Gaeumannomyces graminis	35.01	1.00e-84	308.00
IUUC-Gga-040406	Gallus gallus	92.48	0.00e+00	1408.00
IUUC-Gac-042141	Gasterosteus aculeatus	73.96	0.00e+00	1056.00
IUUC-Ggo-045504	Gorilla gorilla	80.59	0.00e+00	1213.00
IUUC-Hsa-045786	Homo sapiens	81.02	0.00e+00	1218.00
IUUC-Itr-048050	Ictidomys tridecemlineatus	77.95	0.00e+00	1086.00
IUUC-Lch-049824	Latimeria chalumnae	78.30	0.00e+00	1066.00
IUUC-Loc-052173	Lepisosteus oculatus	75.30	0.00e+00	1127.00
IUUC-Laf-054017	Loxodonta africana	84.23	0.00e+00	1185.00
IUUC-Mcc-055713	Macaca mulatta	80.77	0.00e+00	1192.00
IUUC-Meu-056212	Macropus eugenii	70.70	9.00e-107	380.00
IUUC-Mla-059187	Melampsora laricipopulina	42.23	1.00e-78	286.00
IUUC-Mga-059884	Meleagris gallopavo	83.90	0.00e+00	1213.00
IUUC-Mmr-061344	Microcebus murinus	82.29	0.00e+00	1221.00
IUUC-Mdo-062653	Monodelphis domestica	81.43	0.00e+00	1216.00
IUUC-Mmu-063775	Mus musculus	80.22	0.00e+00	1143.00
IUUC-Mpu-066069	Mustela putorius furo	84.26	0.00e+00	1153.00
IUUC-Mlu-067925	Myotis lucifugus	82.04	0.00e+00	1212.00
IUUC-Ncr-068903	Neurospora crassa	35.98	1.00e-80	295.00
IUUC-Nle-070046	Nomascus leucogenys	80.98	0.00e+00	1226.00
IUUC-Opr-071085	Ochotona princeps	89.00	7.00e-112	397.00
IUUC-Ont-072126	Oreochromis niloticus	71.50	0.00e+00	1120.00
IUUC-Oan-072933	Ornithorhynchus anatinus	83.90	0.00e+00	1100.00
IUUC-Ocu-073800	Oryctolagus cuniculus	84.41	0.00e+00	1144.00
IUUC-Ola-086988	Oryzias latipes	74.28	0.00e+00	1071.00
IUUC-Oga-088117	Otolemur garnettii	84.27	0.00e+00	989.00
IUUC-Oar-089371	Ovis aries	82.04	0.00e+00	1200.00
IUUC-Ptr-090551	Pan troglodytes	79.92	0.00e+00	1170.00
IUUC-Pan-092067	Papio anubis	81.21	0.00e+00	1197.00
IUUC-Psi-092963	Pelodiscus sinensis	85.70	0.00e+00	1236.00
IUUC-Pfo-096562	Poecilia formosa	68.64	0.00e+00	1067.00
IUUC-Pab-098680	Pongo abelii	81.02	0.00e+00	1219.00
IUUC-Pca-100986	Procavia capensis	67.44	0.00e+00	801.00
IUUC-Pva-102219	Pteropus vampyrus	67.80	0.00e+00	897.00
IUUC-Pgr-103315	Puccinia graminis	34.53	3.00e-79	290.00
IUUC-Ptt-103736	Puccinia triticina	37.97	5.00e-79	289.00
IUUC-Rno-105270	Rattus norvegicus	80.08	0.00e+00	1147.00
IUUC-Sha-106819	Sarcophilus harrisii	82.99	0.00e+00	1256.00
IUUC-Spo-108271	Schizosaccharomyces pombe	32.03	2.00e-73	270.00
IUUC-Sar-113134	Sorex araneus	74.56	0.00e+00	1065.00
IUUC-Ssc-115441	Sus scrofa	82.17	0.00e+00	1216.00
IUUC-Tgu-117166	Taeniopygia guttata	94.65	0.00e+00	1394.00
IUUC-Tsy-118898	Tarsius syrichta	69.92	0.00e+00	940.00
IUUC-Tvi-122644	Trichoderma virens	37.20	4.00e-82	300.00
IUUC-Tme-127004	Tuber melanosporum	35.14	6.00e-90	326.00
IUUC-Tbe-127292	Tupaia belangeri	64.63	0.00e+00	870.00
IUUC-Ttr-128352	Tursiops truncatus	78.64	0.00e+00	1158.00
IUUC-Vpa-130218	Vicugna pacos	82.37	0.00e+00	903.00
IUUC-Xtr-132594	Xenopus tropicalis	77.08	0.00e+00	1162.00
IUUC-Xma-134157	Xiphophorus maculatus	72.70	0.00e+00	986.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence