iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059312

Ensembl Protein ID

ENSMGAP00000003065.1

UniProt Accession

G1MWE2; G1MWE2_MELGA

Protein Name

Inhibitor of growth protein

Gene Name

ING5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000003364.1	ENSMGAT00000003759.1	ENSMGAP00000003065.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.80e-09	37.4	151	198

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C  ewfH+aC+ l+   ++p+ + w+Cp+C +
   Q: 151  TYC-LCHQVSYGE--MIGCDNpdCPiEWFHFACVDLT---TKPKGK-WFCPRCVQ 198
           69*.*******99..*********99***********...999997.******87 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

DKKAEIDRLA AEYIESVKNM SAEQRVEHLR RIQSAYGKCK EYSDDKVQLA MQTYEMVDKH 60
IRRLDADLAR FEADLKDKLE GSDFESSGSR NLKKGKSQKD KRSSRGRGKR TSEEDTPKKK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGATAAGAAA GCCGAAATTG ACCGCCTGGC CGCGGAGTAC ATCGAGTCGG TGAAGAACAT 60
GTCAGCCGAG CAGCGAGTGG AGCACCTGAG GAGGATCCAG AGCGCCTACG GTAAATGCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028638--ING5
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0070776--C:MOZ/MORF histone acetyltransferase complex
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0016573--P:histone acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:2001235--P:positive regulation of apoptotic signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002381	Ailuropoda melanoleuca	88.12	1.00e-90	325.00
IUUC-Apl-003516	Anas platyrhynchos	92.08	3.00e-101	360.00
IUUC-Aca-005009	Anolis carolinensis	83.17	1.00e-91	328.00
IUUC-Ame-011879	Astyanax mexicanus	71.08	9.00e-85	305.00
IUUC-Bta-012590	Bos taurus	89.11	1.00e-96	345.00
IUUC-Cja-019518	Callithrix jacchus	88.12	4.00e-99	353.00
IUUC-Cfa-020620	Canis familiaris	89.60	1.00e-103	368.00
IUUC-Cpo-022085	Cavia porcellus	90.10	3.00e-93	333.00
IUUC-Csa-023421	Chlorocebus sabaeus	89.11	8.00e-92	328.00
IUUC-Dre-027588	Danio rerio	70.24	2.00e-83	301.00
IUUC-Dor-030910	Dipodomys ordii	59.90	3.00e-67	247.00
IUUC-Eca-033493	Equus caballus	88.12	9.00e-98	348.00
IUUC-Fca-035635	Felis catus	96.10	5.00e-46	177.00
IUUC-Fal-036998	Ficedula albicollis	93.56	9.00e-102	362.00
IUUC-Gmo-039035	Gadus morhua	72.06	3.00e-82	297.00
IUUC-Gga-040578	Gallus gallus	98.51	2.00e-106	377.00
IUUC-Gac-042172	Gasterosteus aculeatus	72.55	1.00e-89	322.00
IUUC-Hsa-045965	Homo sapiens	89.11	8.00e-92	328.00
IUUC-Loc-052725	Lepisosteus oculatus	79.21	2.00e-82	298.00
IUUC-Mcc-055455	Macaca mulatta	89.11	2.00e-91	327.00
IUUC-Mtr-058089	Medicago truncatula	40.00	1.00e-32	132.00
IUUC-Mmr-061351	Microcebus murinus	89.11	3.00e-91	327.00
IUUC-Mdo-062282	Monodelphis domestica	89.60	2.00e-93	334.00
IUUC-Mmu-063201	Mus musculus	88.61	1.00e-95	342.00
IUUC-Mpu-066302	Mustela putorius furo	89.11	6.00e-93	332.00
IUUC-Mlu-068192	Myotis lucifugus	91.58	3.00e-94	337.00
IUUC-Ont-072055	Oreochromis niloticus	72.06	5.00e-81	293.00
IUUC-Oan-073652	Ornithorhynchus anatinus	90.59	4.00e-98	350.00
IUUC-Ocu-073871	Oryctolagus cuniculus	88.67	5.00e-96	343.00
IUUC-Ola-087103	Oryzias latipes	69.12	3.00e-77	280.00
IUUC-Olu-087851	Ostreococcus lucimarinus	41.83	5.00e-20	90.50
IUUC-Oga-088066	Otolemur garnettii	89.60	9.00e-93	332.00
IUUC-Ptr-091665	Pan troglodytes	89.11	8.00e-92	328.00
IUUC-Pan-091875	Papio anubis	89.11	8.00e-92	328.00
IUUC-Psi-093904	Pelodiscus sinensis	90.10	2.00e-98	350.00
IUUC-Pfo-096981	Poecilia formosa	74.02	3.00e-81	293.00
IUUC-Pca-100600	Procavia capensis	58.42	5.00e-65	240.00
IUUC-Pva-102282	Pteropus vampyrus	88.12	3.00e-100	357.00
IUUC-Rno-105646	Rattus norvegicus	89.11	9.00e-96	342.00
IUUC-Sha-107031	Sarcophilus harrisii	90.10	1.00e-93	334.00
IUUC-Tgu-116837	Taeniopygia guttata	93.07	3.00e-101	360.00
IUUC-Tru-117974	Takifugu rubripes	69.79	1.00e-79	288.00
IUUC-Tni-120024	Tetraodon nigroviridis	68.23	1.00e-70	259.00
IUUC-Tca-121597	Theobroma cacao	38.79	7.00e-29	120.00
IUUC-Vvi-131487	Vitis vinifera	39.39	5.00e-30	124.00
IUUC-Xtr-132189	Xenopus tropicalis	79.70	5.00e-96	343.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence