iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000018988.8	ENSRNOT00000025683.8	ENSRNOP00000025683.7
ENSRNOG00000018988.8	ENSRNOT00000065058.3	ENSRNOP00000062509.3

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC	RAID2
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.40e-09	37.1	187	234

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C  ewfH+aC+ l+   ++p+ + w+Cp+C +
   Q: 187  TYC-LCHQVSYGE--MIGCDNpdCPiEWFHFACVDLT---TKPKGK-WFCPRCVQ 234
           69*.*******99..*********99***********...999997.******87 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MATAMYLEHY LDSIENLPCE LQRNFQLMRE LDQRTEDKKA EIDILAAEYI STVKTLSSAQ 60
RVEHLQKIQS AYSKCKEYSD DKVQLAMQTY EMVDKHIRRL DADLARFEAD LKDRMDGSDF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCACCGCCC GCTCGCGCAG ACCCCGAGCG TGGCCGCAGC GAAGATGGCG ACTGCCATGT 60
ACTTGGAGCA CTATCTGGAC AGTAAGCACT CTGGCCGAGC CGCCACCCGC GCGGGTCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028638--ING5
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0070776--C:MOZ/MORF histone acetyltransferase complex
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0016573--P:histone acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:2001235--P:positive regulation of apoptotic signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002381	Ailuropoda melanoleuca	92.54	8.00e-109	385.00
IUUC-Apl-003516	Anas platyrhynchos	88.24	2.00e-96	344.00
IUUC-Aca-005009	Anolis carolinensis	85.29	3.00e-111	394.00
IUUC-Ame-011879	Astyanax mexicanus	75.93	2.00e-105	374.00
IUUC-Bta-012590	Bos taurus	93.39	7.00e-114	402.00
IUUC-Cja-019518	Callithrix jacchus	93.75	4.00e-121	427.00
IUUC-Cfa-020620	Canis familiaris	94.58	6.00e-131	459.00
IUUC-Cpo-022085	Cavia porcellus	95.34	2.00e-117	414.00
IUUC-Csa-023421	Chlorocebus sabaeus	94.17	7.00e-118	416.00
IUUC-Dre-027588	Danio rerio	76.45	4.00e-104	370.00
IUUC-Eca-033493	Equus caballus	92.95	7.00e-116	409.00
IUUC-Fca-035635	Felis catus	93.64	1.00e-54	206.00
IUUC-Fal-036998	Ficedula albicollis	89.57	2.00e-111	394.00
IUUC-Gmo-039035	Gadus morhua	75.93	6.00e-103	366.00
IUUC-Gga-040578	Gallus gallus	90.42	7.00e-121	426.00
IUUC-Gac-042172	Gasterosteus aculeatus	75.10	7.00e-105	372.00
IUUC-Hsa-045965	Homo sapiens	94.17	7.00e-118	416.00
IUUC-Loc-052725	Lepisosteus oculatus	82.50	3.00e-104	370.00
IUUC-Mcc-055455	Macaca mulatta	93.01	9.00e-110	389.00
IUUC-Mga-059312	Meleagris gallopavo	89.11	2.00e-97	348.00
IUUC-Mmr-061351	Microcebus murinus	93.39	3.00e-109	387.00
IUUC-Mdo-062282	Monodelphis domestica	92.50	3.00e-115	407.00
IUUC-Mmu-063201	Mus musculus	99.17	2.00e-127	447.00
IUUC-Mpu-066302	Mustela putorius furo	94.17	7.00e-119	419.00
IUUC-Mlu-068192	Myotis lucifugus	95.00	3.00e-119	420.00
IUUC-Ont-072055	Oreochromis niloticus	76.35	1.00e-100	358.00
IUUC-Oan-073652	Ornithorhynchus anatinus	92.98	2.00e-112	397.00
IUUC-Ocu-073871	Oryctolagus cuniculus	92.95	1.00e-120	425.00
IUUC-Oin-079049	Oryza indica	33.99	5.00e-35	140.00
IUUC-Oni-082218	Oryza nivara	33.99	5.00e-35	140.00
IUUC-Ola-087103	Oryzias latipes	75.21	7.00e-97	346.00
IUUC-Oga-088066	Otolemur garnettii	84.08	7.00e-102	362.00
IUUC-Ptr-091665	Pan troglodytes	94.17	7.00e-118	416.00
IUUC-Pan-091875	Papio anubis	94.17	7.00e-118	416.00
IUUC-Psi-093904	Pelodiscus sinensis	89.67	8.00e-102	362.00
IUUC-Pfo-096981	Poecilia formosa	76.76	2.00e-100	358.00
IUUC-Pva-102282	Pteropus vampyrus	89.17	2.00e-123	434.00
IUUC-Sha-107031	Sarcophilus harrisii	90.87	2.00e-107	381.00
IUUC-Smo-109441	Selaginella moellendorffii	36.59	1.00e-42	166.00
IUUC-Tgu-116837	Taeniopygia guttata	88.31	5.00e-111	393.00
IUUC-Tru-117974	Takifugu rubripes	76.03	2.00e-98	352.00
IUUC-Tni-120024	Tetraodon nigroviridis	75.52	4.00e-90	323.00
IUUC-Vvi-131487	Vitis vinifera	35.02	5.00e-33	134.00
IUUC-Xtr-132189	Xenopus tropicalis	81.17	5.00e-111	393.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence