iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-072580

Ensembl Protein ID

ENSONIP00000009629.1

UniProt Accession

I3JL85; I3JL85_ORENI

Genbank Protein ID

ENSONIP00000009629

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01026639

Gene Name

klhl8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000007641.1	ENSONIT00000009635.1	ENSONIP00000009629.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	4.50e-18	65.8	61	126
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.40e-09	35.3	160	191

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l+vg + +++hk+vLa   ++F+a+fl+e++e k ++ +eikd + ++ ++l++F Y++kl++
   Q: 61   CDVTLKVGSRLIQCHKLVLACVIPYFRAMFLSEMSEAK-QELIEIKDFDGDAIQDLVHFAYSSKLTL 126
           9************************************9.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           + Ncl++++fA+ ++  dL+d a+++++ hF+
   Q: 160  PTNCLAVRTFAESHNRVDLMDMADRYACEHFT 191
           78*****************************7 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MAPGDVVPDH AKQLKSKEKR PANRALKSEC EPDGSFVFEA HEAWKDFHNS LRHFYEVGEL 60
CDVTLKVGSR LIQCHKLVLA CVIPYFRAMF LSEMSEAKQE LIEIKDFDGD AIQDLVHFAY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCACCGG GGGATGTGGT GCCAGACCAT GCCAAACAGC TGAAGTCCAA GGAGAAGCGG 60
CCTGCAAACA GGGCTTTGAA ATCAGAATGT GAGCCTGACG GGTCCTTTGT CTTTGAGGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030605--KLHL8
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001443	Ailuropoda melanoleuca	81.46	0.00e+00	1034.00
IUUC-Apl-003978	Anas platyrhynchos	84.02	0.00e+00	1051.00
IUUC-Aca-004958	Anolis carolinensis	78.16	0.00e+00	992.00
IUUC-Ame-011139	Astyanax mexicanus	90.23	0.00e+00	1162.00
IUUC-Bta-013142	Bos taurus	80.88	0.00e+00	1035.00
IUUC-Bdi-014143	Brachypodium distachyon	36.19	6.00e-42	166.00
IUUC-Cel-018551	Caenorhabditis elegans	39.11	7.00e-129	454.00
IUUC-Cja-019650	Callithrix jacchus	81.24	0.00e+00	1055.00
IUUC-Cfa-021046	Canis familiaris	81.68	0.00e+00	1040.00
IUUC-Cpo-022445	Cavia porcellus	80.56	0.00e+00	1010.00
IUUC-Csa-023642	Chlorocebus sabaeus	80.97	0.00e+00	1061.00
IUUC-Cho-025012	Choloepus hoffmanni	66.90	0.00e+00	765.00
IUUC-Dre-027723	Danio rerio	86.86	0.00e+00	1117.00
IUUC-Dno-028964	Dasypus novemcinctus	80.98	0.00e+00	872.00
IUUC-Dor-030899	Dipodomys ordii	72.19	1.00e-117	417.00
IUUC-Ete-032815	Echinops telfairi	79.19	0.00e+00	1029.00
IUUC-Eca-034162	Equus caballus	84.02	0.00e+00	1031.00
IUUC-Eeu-034660	Erinaceus europaeus	80.26	0.00e+00	1032.00
IUUC-Fca-035659	Felis catus	81.95	0.00e+00	1039.00
IUUC-Fal-037619	Ficedula albicollis	81.36	0.00e+00	1061.00
IUUC-Gmo-038546	Gadus morhua	91.57	0.00e+00	1160.00
IUUC-Ggr-040041	Gaeumannomyces graminis	32.88	2.00e-08	53.90
IUUC-Gga-040770	Gallus gallus	81.36	0.00e+00	1042.00
IUUC-Gac-042557	Gasterosteus aculeatus	94.95	0.00e+00	1224.00
IUUC-Ggo-044741	Gorilla gorilla	82.33	0.00e+00	1059.00
IUUC-Hsa-046025	Homo sapiens	82.33	0.00e+00	1059.00
IUUC-Itr-048541	Ictidomys tridecemlineatus	84.34	0.00e+00	978.00
IUUC-Loc-052834	Lepisosteus oculatus	86.32	0.00e+00	1048.00
IUUC-Laf-054513	Loxodonta africana	81.46	0.00e+00	1048.00
IUUC-Mcc-054707	Macaca mulatta	80.81	0.00e+00	1057.00
IUUC-Meu-056779	Macropus eugenii	85.49	0.00e+00	1058.00
IUUC-Mtr-058180	Medicago truncatula	33.21	5.00e-36	146.00
IUUC-Mga-059676	Meleagris gallopavo	80.88	0.00e+00	1038.00
IUUC-Mmr-061359	Microcebus murinus	82.17	0.00e+00	1025.00
IUUC-Mdo-062527	Monodelphis domestica	84.31	0.00e+00	1046.00
IUUC-Mmu-063112	Mus musculus	83.28	0.00e+00	1051.00
IUUC-Mpu-065800	Mustela putorius furo	81.38	0.00e+00	1038.00
IUUC-Mlu-067536	Myotis lucifugus	83.89	0.00e+00	1003.00
IUUC-Nle-069397	Nomascus leucogenys	82.33	0.00e+00	1059.00
IUUC-Opr-070599	Ochotona princeps	81.65	0.00e+00	866.00
IUUC-Oan-073180	Ornithorhynchus anatinus	81.29	0.00e+00	1056.00
IUUC-Ocu-074026	Oryctolagus cuniculus	82.26	0.00e+00	1026.00
IUUC-Ola-086776	Oryzias latipes	92.47	0.00e+00	1146.00
IUUC-Oga-088651	Otolemur garnettii	80.52	0.00e+00	1035.00
IUUC-Oar-089567	Ovis aries	79.74	0.00e+00	1014.00
IUUC-Ptr-091564	Pan troglodytes	82.33	0.00e+00	1059.00
IUUC-Pan-092578	Papio anubis	80.97	0.00e+00	1061.00
IUUC-Psi-093635	Pelodiscus sinensis	80.81	0.00e+00	1001.00
IUUC-Pma-094660	Petromyzon marinus	59.53	0.00e+00	741.00
IUUC-Pfo-097507	Poecilia formosa	96.00	0.00e+00	1157.00
IUUC-Pab-098025	Pongo abelii	82.33	0.00e+00	1059.00
IUUC-Pca-101046	Procavia capensis	75.07	8.00e-160	557.00
IUUC-Pva-102359	Pteropus vampyrus	85.23	0.00e+00	805.00
IUUC-Rno-105750	Rattus norvegicus	83.62	0.00e+00	1044.00
IUUC-Sha-107513	Sarcophilus harrisii	81.29	0.00e+00	1056.00
IUUC-Stu-112032	Solanum tuberosum	31.23	6.00e-40	159.00
IUUC-Ssc-116205	Sus scrofa	81.29	0.00e+00	863.00
IUUC-Tgu-117435	Taeniopygia guttata	81.20	0.00e+00	1063.00
IUUC-Tru-118709	Takifugu rubripes	94.46	0.00e+00	1207.00
IUUC-Tsy-119466	Tarsius syrichta	84.85	0.00e+00	977.00
IUUC-Tni-119988	Tetraodon nigroviridis	94.96	0.00e+00	1209.00
IUUC-Tbe-127704	Tupaia belangeri	83.03	0.00e+00	933.00
IUUC-Ttr-128892	Tursiops truncatus	82.94	0.00e+00	805.00
IUUC-Vpa-130545	Vicugna pacos	81.85	0.00e+00	870.00
IUUC-Xtr-132289	Xenopus tropicalis	79.41	0.00e+00	986.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence