iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093635

Ensembl Protein ID

ENSPSIP00000015466.1

UniProt Accession

K7G5A5; K7G5A5_PELSI

Genbank Protein ID

ENSPSIP00000015466

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01034607

Gene Name

KLHL8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000013743.1	ENSPSIT00000015538.1	ENSPSIP00000015466.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.30e-17	63.1	142	207
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	6.60e-10	38.1	241	272

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l+vg + +++hk+vLa   ++F+a+fl+e+ e k +  +eikd + ++ ++l+kF+Y+++l++
   Q: 142  CDVTLKVGSKLISCHKLVLACVIPYFRAMFLSEMAEAK-QTLIEIKDFDGDAIEDLVKFVYSSQLTL 207
           9************************************9.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Ncl++++fA+ ++  dL+d a+++++ hF+
   Q: 241  PSNCLAVRAFAESHNRIDLMDMADRYACEHFT 272
           89*****************************7 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MELRMCQRSS SLASSQPRSS DAVLCQESSA HAREAAPGET VAAGLLPPAV PWALGERRRR 60
RVAQRAGVFE YSCCERRKHP MASESMIPES AKHYQIKGKR RQQQQDRSLN SDGEEVFVFE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCGCCTCCT CGCGCCTCGA TGGAACTGCG CATGTGCCAG CGATCTTCCT CTCTCGCCTC 60
CTCCCAGCCG CGTAGTTCTG ATGCCGTCCT CTGTCAGGAA AGCAGCGCGC ATGCGCGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030605--KLHL8
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005654--C:nucleoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001443	Ailuropoda melanoleuca	89.32	0.00e+00	1117.00
IUUC-Atr-002726	Amborella trichopoda	38.36	5.00e-43	169.00
IUUC-Apl-003978	Anas platyrhynchos	89.90	0.00e+00	1115.00
IUUC-Aca-004958	Anolis carolinensis	87.07	0.00e+00	1077.00
IUUC-Ame-011139	Astyanax mexicanus	81.76	0.00e+00	1032.00
IUUC-Bta-013142	Bos taurus	89.29	0.00e+00	1110.00
IUUC-Bol-015710	Brassica oleracea	24.91	2.00e-11	63.20
IUUC-Cel-018551	Caenorhabditis elegans	39.76	7.00e-129	454.00
IUUC-Cja-019650	Callithrix jacchus	88.44	0.00e+00	1115.00
IUUC-Cfa-021046	Canis familiaris	89.47	0.00e+00	1113.00
IUUC-Cpo-022445	Cavia porcellus	87.63	0.00e+00	1069.00
IUUC-Csa-023642	Chlorocebus sabaeus	88.94	0.00e+00	1120.00
IUUC-Cho-025012	Choloepus hoffmanni	73.36	0.00e+00	812.00
IUUC-Dre-027723	Danio rerio	79.90	0.00e+00	1010.00
IUUC-Dno-028964	Dasypus novemcinctus	89.02	0.00e+00	954.00
IUUC-Dor-030899	Dipodomys ordii	78.02	5.00e-121	427.00
IUUC-Dse-031158	Dothistroma septosporum	31.08	4.00e-05	41.60
IUUC-Ete-032815	Echinops telfairi	87.08	0.00e+00	1088.00
IUUC-Eca-034162	Equus caballus	89.49	0.00e+00	1096.00
IUUC-Eeu-034660	Erinaceus europaeus	88.29	0.00e+00	1098.00
IUUC-Fca-035659	Felis catus	89.15	0.00e+00	1113.00
IUUC-Fal-037619	Ficedula albicollis	91.74	0.00e+00	1147.00
IUUC-Gmo-038546	Gadus morhua	83.78	0.00e+00	1004.00
IUUC-Gga-040770	Gallus gallus	89.80	0.00e+00	1108.00
IUUC-Gac-042557	Gasterosteus aculeatus	78.43	0.00e+00	1001.00
IUUC-Ggo-044741	Gorilla gorilla	88.94	0.00e+00	1121.00
IUUC-Hsa-046025	Homo sapiens	88.94	0.00e+00	1121.00
IUUC-Itr-048541	Ictidomys tridecemlineatus	92.69	0.00e+00	1028.00
IUUC-Loc-052834	Lepisosteus oculatus	83.05	0.00e+00	994.00
IUUC-Lma-052959	Leptosphaeria maculans	30.56	3.00e-06	45.40
IUUC-Laf-054513	Loxodonta africana	88.59	0.00e+00	1104.00
IUUC-Mcc-054707	Macaca mulatta	88.78	0.00e+00	1117.00
IUUC-Meu-056779	Macropus eugenii	88.98	0.00e+00	1110.00
IUUC-Mtr-058180	Medicago truncatula	33.33	2.00e-36	146.00
IUUC-Mga-059676	Meleagris gallopavo	89.63	0.00e+00	1109.00
IUUC-Mmr-061359	Microcebus murinus	88.16	0.00e+00	1092.00
IUUC-Mdo-062527	Monodelphis domestica	88.61	0.00e+00	1113.00
IUUC-Mmu-063112	Mus musculus	85.81	0.00e+00	1088.00
IUUC-Mac-064682	Musa acuminata	36.52	1.00e-41	164.00
IUUC-Mpu-065800	Mustela putorius furo	88.98	0.00e+00	1112.00
IUUC-Mlu-067536	Myotis lucifugus	87.29	0.00e+00	1077.00
IUUC-Nle-069397	Nomascus leucogenys	88.94	0.00e+00	1120.00
IUUC-Opr-070599	Ochotona princeps	87.87	0.00e+00	946.00
IUUC-Ont-072580	Oreochromis niloticus	80.81	0.00e+00	1018.00
IUUC-Oan-073180	Ornithorhynchus anatinus	90.44	0.00e+00	1117.00
IUUC-Ocu-074026	Oryctolagus cuniculus	88.64	0.00e+00	1087.00
IUUC-Obr-076181	Oryza brachyantha	32.03	6.00e-36	146.00
IUUC-Ola-086776	Oryzias latipes	79.73	0.00e+00	967.00
IUUC-Oga-088651	Otolemur garnettii	89.19	0.00e+00	1103.00
IUUC-Oar-089567	Ovis aries	88.10	0.00e+00	1085.00
IUUC-Ptr-091564	Pan troglodytes	88.94	0.00e+00	1121.00
IUUC-Pan-092578	Papio anubis	88.94	0.00e+00	1120.00
IUUC-Pma-094660	Petromyzon marinus	61.14	0.00e+00	721.00
IUUC-Pfo-097507	Poecilia formosa	80.59	0.00e+00	982.00
IUUC-Pab-098025	Pongo abelii	88.94	0.00e+00	1121.00
IUUC-Pca-101046	Procavia capensis	81.25	4.00e-164	570.00
IUUC-Ppe-101154	Prunus persica	34.35	8.00e-39	155.00
IUUC-Pva-102359	Pteropus vampyrus	92.27	0.00e+00	865.00
IUUC-Rno-105750	Rattus norvegicus	86.45	0.00e+00	1079.00
IUUC-Sha-107513	Sarcophilus harrisii	90.95	0.00e+00	1133.00
IUUC-Sly-111482	Solanum lycopersicum	33.91	5.00e-41	162.00
IUUC-Stu-112032	Solanum tuberosum	34.78	4.00e-42	166.00
IUUC-Sar-113616	Sorex araneus	67.24	4.00e-113	401.00
IUUC-Ssc-116205	Sus scrofa	88.87	0.00e+00	957.00
IUUC-Tgu-117435	Taeniopygia guttata	90.91	0.00e+00	1125.00
IUUC-Tru-118709	Takifugu rubripes	80.10	0.00e+00	1005.00
IUUC-Tsy-119466	Tarsius syrichta	92.68	0.00e+00	1024.00
IUUC-Tni-119988	Tetraodon nigroviridis	79.46	0.00e+00	1000.00
IUUC-Tbe-127704	Tupaia belangeri	90.56	0.00e+00	982.00
IUUC-Ttr-128892	Tursiops truncatus	91.47	0.00e+00	845.00
IUUC-Vpa-130545	Vicugna pacos	89.43	0.00e+00	961.00
IUUC-Xtr-132289	Xenopus tropicalis	84.11	0.00e+00	1033.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence