iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
miRNAMap	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	5.20e-17	62.4	68	133
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.40e-09	37.1	167	198

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l+vg + +++hk+ La   ++F+a+fl+e++e k +  +ei+d + +++++l+kF+Y+++l++
   Q: 68   CDVTLKVGSKLISCHKLALACVIPYFRAMFLSEMSEAK-QALIEIRDFDGDAVEDLVKFVYSSRLTL 133
           9************************************9.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Ncl++++fA+ ++ +dL+d a+ +++ hF+
   Q: 167  PSNCLAVRAFAESHNRTDLMDMADQYACEHFT 198
           89*****************************7 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MASESTNGKL ARSHVTKGRR QQQQQQQVRS RSSVSECDGD DSFIFEANEA WKDFHGSLLG 60
FYENGELCDV TLKVGSKLIS CHKLALACVI PYFRAMFLSE MSEAKQALIE IRDFDGDAVE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCTCCGCG GAGCCGGGCA CGAGCAAGCG GGCGGGCAAG TGAGCGCGTC CGCCGAGTGT 60
CGGAGCTGGG CTGGCGCGGC GCCGGCACGG AGCGGGTGTG GCGGCTCGGC CTGCGCGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030605--KLHL8
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005654--C:nucleoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

rno:289457

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001443	Ailuropoda melanoleuca	93.40	0.00e+00	1170.00
IUUC-Atr-002726	Amborella trichopoda	36.32	6.00e-42	166.00
IUUC-Apl-003978	Anas platyrhynchos	87.76	0.00e+00	1130.00
IUUC-Aca-004958	Anolis carolinensis	87.65	0.00e+00	1055.00
IUUC-Ame-011139	Astyanax mexicanus	85.15	0.00e+00	1058.00
IUUC-Bta-013142	Bos taurus	92.59	0.00e+00	1171.00
IUUC-Cel-018551	Caenorhabditis elegans	40.27	2.00e-128	453.00
IUUC-Cja-019650	Callithrix jacchus	92.27	0.00e+00	1186.00
IUUC-Cfa-021046	Canis familiaris	93.56	0.00e+00	1174.00
IUUC-Cpo-022445	Cavia porcellus	91.63	0.00e+00	1130.00
IUUC-Csa-023642	Chlorocebus sabaeus	92.91	0.00e+00	1194.00
IUUC-Cho-025012	Choloepus hoffmanni	77.30	0.00e+00	872.00
IUUC-Dre-027723	Danio rerio	82.76	0.00e+00	1045.00
IUUC-Dno-028964	Dasypus novemcinctus	90.86	0.00e+00	966.00
IUUC-Dor-030899	Dipodomys ordii	82.45	7.00e-135	474.00
IUUC-Ete-032815	Echinops telfairi	90.18	0.00e+00	1155.00
IUUC-Eca-034162	Equus caballus	93.40	0.00e+00	1161.00
IUUC-Eeu-034660	Erinaceus europaeus	91.47	0.00e+00	1153.00
IUUC-Fca-035659	Felis catus	93.72	0.00e+00	1174.00
IUUC-Fal-037619	Ficedula albicollis	87.30	0.00e+00	1125.00
IUUC-Gmo-038546	Gadus morhua	83.96	0.00e+00	1043.00
IUUC-Gga-040770	Gallus gallus	87.78	0.00e+00	1107.00
IUUC-Gac-042557	Gasterosteus aculeatus	81.91	0.00e+00	1028.00
IUUC-Ggo-044741	Gorilla gorilla	92.75	0.00e+00	1193.00
IUUC-Hsa-046025	Homo sapiens	92.59	0.00e+00	1191.00
IUUC-Itr-048541	Ictidomys tridecemlineatus	95.63	0.00e+00	1083.00
IUUC-Loc-052834	Lepisosteus oculatus	85.64	0.00e+00	991.00
IUUC-Laf-054513	Loxodonta africana	92.91	0.00e+00	1173.00
IUUC-Mcc-054707	Macaca mulatta	92.75	0.00e+00	1190.00
IUUC-Meu-056779	Macropus eugenii	87.78	0.00e+00	1129.00
IUUC-Mga-059676	Meleagris gallopavo	87.62	0.00e+00	1106.00
IUUC-Mmr-061359	Microcebus murinus	92.11	0.00e+00	1148.00
IUUC-Mdo-062527	Monodelphis domestica	86.52	0.00e+00	1121.00
IUUC-Mmu-063112	Mus musculus	96.98	0.00e+00	1233.00
IUUC-Mac-064682	Musa acuminata	35.93	3.00e-42	166.00
IUUC-Mpu-065800	Mustela putorius furo	92.91	0.00e+00	1165.00
IUUC-Mlu-067536	Myotis lucifugus	92.05	0.00e+00	1122.00
IUUC-Nle-069397	Nomascus leucogenys	92.91	0.00e+00	1194.00
IUUC-Opr-070599	Ochotona princeps	91.42	0.00e+00	962.00
IUUC-Ont-072580	Oreochromis niloticus	83.62	0.00e+00	1044.00
IUUC-Oan-073180	Ornithorhynchus anatinus	91.92	0.00e+00	1130.00
IUUC-Ocu-074026	Oryctolagus cuniculus	93.08	0.00e+00	1161.00
IUUC-Ola-086776	Oryzias latipes	82.76	0.00e+00	998.00
IUUC-Oga-088651	Otolemur garnettii	94.04	0.00e+00	1172.00
IUUC-Oar-089567	Ovis aries	91.63	0.00e+00	1147.00
IUUC-Ptr-091564	Pan troglodytes	92.75	0.00e+00	1193.00
IUUC-Pan-092578	Papio anubis	92.91	0.00e+00	1194.00
IUUC-Psi-093635	Pelodiscus sinensis	86.45	0.00e+00	1061.00
IUUC-Pma-094660	Petromyzon marinus	61.38	0.00e+00	757.00
IUUC-Pfo-097507	Poecilia formosa	83.55	0.00e+00	976.00
IUUC-Pab-098025	Pongo abelii	92.75	0.00e+00	1193.00
IUUC-Pca-101046	Procavia capensis	84.93	4.00e-179	621.00
IUUC-Ppe-101154	Prunus persica	31.89	4.00e-38	153.00
IUUC-Pva-102359	Pteropus vampyrus	95.45	0.00e+00	887.00
IUUC-Sha-107513	Sarcophilus harrisii	88.75	0.00e+00	1136.00
IUUC-Sly-111482	Solanum lycopersicum	31.52	6.00e-41	162.00
IUUC-Stu-112032	Solanum tuberosum	32.68	2.00e-42	167.00
IUUC-Sar-113616	Sorex araneus	70.31	3.00e-116	412.00
IUUC-Ssc-116205	Sus scrofa	92.61	0.00e+00	976.00
IUUC-Tgu-117435	Taeniopygia guttata	87.78	0.00e+00	1126.00
IUUC-Tru-118709	Takifugu rubripes	82.42	0.00e+00	1033.00
IUUC-Tsy-119466	Tarsius syrichta	95.99	0.00e+00	1083.00
IUUC-Tni-119988	Tetraodon nigroviridis	82.45	0.00e+00	1030.00
IUUC-Tbe-127704	Tupaia belangeri	94.16	0.00e+00	1039.00
IUUC-Ttr-128892	Tursiops truncatus	95.25	0.00e+00	905.00
IUUC-Vpa-130545	Vicugna pacos	92.79	0.00e+00	978.00
IUUC-Xtr-132289	Xenopus tropicalis	81.99	0.00e+00	997.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence