iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005326

UUCD1 version

UUC-AnC-00680

Ensembl Protein ID

ENSACAP00000009775.2

UniProt Accession

G1KJJ1; G1KJJ1_ANOCA

Protein Name

Uncharacterized protein

Gene Name

RNF139

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000009979.2	ENSACAT00000009974.2	ENSACAP00000009775.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.60e-08	33.1	552	590

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           CaiC+ +f    +++pC+H fha Cl kw       + +++CP C
   Q: 552  CAICYHEFTVSARITPCNHYFHALCLRKW------LYIQDTCPMC 590
           ********88899****************......********** PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

GMAAPDPPQA PPLRLGPRLW AGVEVALRVP SLFLIDAIFN SPPAFPGESL WNSLLGALLR 60
LMGVFVFMVV LVLSQRALFR FYVISCALLL AATSVLVNYY AFLHINFHSA SYTTAFGVQL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGATGGCGG CCCCGGACCC CCCTCAGGCG CCGCCTCTAC GGCTAGGCCC ACGGCTCTGG 60
GCCGGCGTGG AGGTGGCGCT GCGGGTGCCC AGCCTCTTCC TCATCGACGC CATCTTCAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR025754--TRC8_N_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13705--TRC8_N
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0005783--C:endoplasmic reticulum
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0036503--P:ERAD pathway
GO:0008285--P:negative regulation of cell proliferation
GO:0017148--P:negative regulation of translation
GO:2000060--P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0031648--P:protein destabilization
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0060628--P:regulation of ER to Golgi vesicle-mediated transport
GO:0070613--P:regulation of protein processing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002401	Ailuropoda melanoleuca	76.59	0.00e+00	922.00
IUUC-Apl-004214	Anas platyrhynchos	86.18	0.00e+00	943.00
IUUC-Ame-011687	Astyanax mexicanus	71.45	0.00e+00	816.00
IUUC-Bta-013394	Bos taurus	76.43	0.00e+00	943.00
IUUC-Cja-019499	Callithrix jacchus	77.07	0.00e+00	956.00
IUUC-Cfa-020357	Canis familiaris	76.43	0.00e+00	921.00
IUUC-Cpo-021924	Cavia porcellus	79.39	0.00e+00	936.00
IUUC-Csa-023513	Chlorocebus sabaeus	76.27	0.00e+00	942.00
IUUC-Cho-024285	Choloepus hoffmanni	70.54	0.00e+00	800.00
IUUC-Cin-025223	Ciona intestinalis	53.18	1.00e-73	269.00
IUUC-Csv-026018	Ciona savignyi	46.98	1.00e-65	243.00
IUUC-Cgl-026601	Colletotrichum gloeosporioides	36.00	8.00e-08	52.00
IUUC-Dre-028660	Danio rerio	69.74	0.00e+00	732.00
IUUC-Dno-029463	Dasypus novemcinctus	82.65	3.00e-108	385.00
IUUC-Dor-030728	Dipodomys ordii	81.23	0.00e+00	913.00
IUUC-Dme-032186	Drosophila melanogaster	46.21	8.00e-100	358.00
IUUC-Ete-032368	Echinops telfairi	77.81	0.00e+00	922.00
IUUC-Eca-034325	Equus caballus	76.75	0.00e+00	909.00
IUUC-Fca-035537	Felis catus	76.12	0.00e+00	915.00
IUUC-Fal-037459	Ficedula albicollis	86.72	0.00e+00	935.00
IUUC-Fso-038284	Fusarium solani	34.57	9.00e-10	58.50
IUUC-Gmo-039442	Gadus morhua	79.40	1.00e-99	357.00
IUUC-Ggr-039921	Gaeumannomyces graminis	33.96	9.00e-08	52.40
IUUC-Gga-041071	Gallus gallus	84.80	0.00e+00	983.00
IUUC-Gac-042483	Gasterosteus aculeatus	67.46	0.00e+00	841.00
IUUC-Ggo-044672	Gorilla gorilla	76.27	0.00e+00	940.00
IUUC-Hsa-045836	Homo sapiens	75.96	0.00e+00	917.00
IUUC-Itr-048588	Ictidomys tridecemlineatus	79.26	0.00e+00	960.00
IUUC-Lch-050073	Latimeria chalumnae	74.45	0.00e+00	915.00
IUUC-Loc-052908	Lepisosteus oculatus	73.98	0.00e+00	884.00
IUUC-Laf-053519	Loxodonta africana	76.11	0.00e+00	949.00
IUUC-Mcc-054674	Macaca mulatta	63.59	5.00e-52	196.00
IUUC-Mor-057262	Magnaporthe oryzae	30.19	2.00e-09	57.80
IUUC-Mpo-057601	Magnaporthe poae	36.73	4.00e-09	56.20
IUUC-Mga-059922	Meleagris gallopavo	87.36	0.00e+00	932.00
IUUC-Mmr-061452	Microcebus murinus	77.63	0.00e+00	926.00
IUUC-Mdo-062412	Monodelphis domestica	77.92	0.00e+00	955.00
IUUC-Mmu-063147	Mus musculus	77.61	0.00e+00	944.00
IUUC-Mpu-065929	Mustela putorius furo	77.50	0.00e+00	919.00
IUUC-Mlu-067899	Myotis lucifugus	77.65	0.00e+00	926.00
IUUC-Nle-070083	Nomascus leucogenys	76.27	0.00e+00	942.00
IUUC-Opr-070461	Ochotona princeps	75.65	0.00e+00	930.00
IUUC-Ont-072256	Oreochromis niloticus	69.57	0.00e+00	845.00
IUUC-Oan-073150	Ornithorhynchus anatinus	81.45	0.00e+00	866.00
IUUC-Ocu-073748	Oryctolagus cuniculus	77.31	0.00e+00	912.00
IUUC-Oga-088565	Otolemur garnettii	76.27	0.00e+00	942.00
IUUC-Oar-089432	Ovis aries	80.24	0.00e+00	935.00
IUUC-Ptr-091422	Pan troglodytes	76.11	0.00e+00	941.00
IUUC-Pan-092331	Papio anubis	76.27	0.00e+00	942.00
IUUC-Psi-092933	Pelodiscus sinensis	87.76	0.00e+00	961.00
IUUC-Pfo-097466	Poecilia formosa	68.24	0.00e+00	837.00
IUUC-Pab-098702	Pongo abelii	76.27	0.00e+00	939.00
IUUC-Pca-100125	Procavia capensis	77.18	0.00e+00	941.00
IUUC-Pva-102628	Pteropus vampyrus	76.18	0.00e+00	926.00
IUUC-Rno-104886	Rattus norvegicus	75.80	0.00e+00	957.00
IUUC-Sha-106702	Sarcophilus harrisii	78.45	0.00e+00	943.00
IUUC-Ssc-116164	Sus scrofa	78.89	0.00e+00	952.00
IUUC-Tgu-116829	Taeniopygia guttata	85.02	0.00e+00	957.00
IUUC-Tru-118557	Takifugu rubripes	69.67	0.00e+00	817.00
IUUC-Tsy-119399	Tarsius syrichta	75.74	3.00e-157	547.00
IUUC-Tni-120006	Tetraodon nigroviridis	64.34	0.00e+00	719.00
IUUC-Tbe-127664	Tupaia belangeri	77.54	0.00e+00	920.00
IUUC-Ttr-129144	Tursiops truncatus	78.52	0.00e+00	970.00
IUUC-Vpa-130226	Vicugna pacos	76.43	0.00e+00	942.00
IUUC-Xtr-132461	Xenopus tropicalis	74.04	0.00e+00	848.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence