iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059922

UUCD1 version

UUC-MeG-00713

Ensembl Protein ID

ENSMGAP00000016810.1

UniProt Accession

G1NRT1; G1NRT1_MELGA

Protein Name

Uncharacterized protein

Gene Name

RNF139

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000015869.1	ENSMGAT00000017784.1	ENSMGAP00000016810.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.90e-09	35.3	490	528

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           CaiC+ +f +  +++pC+H fha Cl kw       + +++CP C
   Q: 490  CAICYHEFTTSARITPCNHYFHALCLRKW------LYIQDTCPMC 528
           ********999******************......********** PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

GVFLSSIVLV LQQRALFKFY MIASAFLLAA TSVLVNYYAS LHINFYSAYY TAAFGIQFLP 60
HKGPSLWMAL SILQLTFGIG YVTLLNMQSV YSQLIILDIL IPVIGLVVEL PLHVRQMLVF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTGTCTTTC TATCCAGCAT TGTTCTGGTG TTACAACAGC GAGCACTTTT CAAGTTTTAT 60
ATGATCGCCT CGGCATTTCT GCTGGCTGCA ACTTCAGTGT TGGTGAATTA CTATGCTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR025754--TRC8_N_dom
IPR001841--Znf_RING
IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13705--TRC8_N
PF13639--zf-RING_2

SMART

SM00184--RING
SM00744--RINGv

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0016021--C:integral component of membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0036503--P:ERAD pathway
GO:0008285--P:negative regulation of cell proliferation
GO:0017148--P:negative regulation of translation
GO:2000060--P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0031648--P:protein destabilization
GO:0060628--P:regulation of ER to Golgi vesicle-mediated transport
GO:0070613--P:regulation of protein processing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002401	Ailuropoda melanoleuca	80.83	0.00e+00	971.00
IUUC-Apl-004214	Anas platyrhynchos	94.61	0.00e+00	1073.00
IUUC-Aca-005326	Anolis carolinensis	87.36	0.00e+00	988.00
IUUC-Ame-011687	Astyanax mexicanus	77.43	0.00e+00	843.00
IUUC-Bta-013394	Bos taurus	81.09	0.00e+00	999.00
IUUC-Bci-013813	Botrytis cinerea	62.96	2.00e-07	49.70
IUUC-Cja-019499	Callithrix jacchus	80.07	0.00e+00	999.00
IUUC-Cfa-020357	Canis familiaris	81.71	0.00e+00	978.00
IUUC-Cpo-021924	Cavia porcellus	80.10	0.00e+00	1011.00
IUUC-Csa-023513	Chlorocebus sabaeus	81.22	0.00e+00	998.00
IUUC-Cho-024285	Choloepus hoffmanni	74.84	0.00e+00	850.00
IUUC-Cin-025223	Ciona intestinalis	53.18	8.00e-74	269.00
IUUC-Csv-026018	Ciona savignyi	47.62	1.00e-65	242.00
IUUC-Cgl-026601	Colletotrichum gloeosporioides	36.00	2.00e-07	50.80
IUUC-Dre-028660	Danio rerio	70.20	0.00e+00	755.00
IUUC-Dno-029463	Dasypus novemcinctus	82.91	5.00e-114	404.00
IUUC-Dor-030728	Dipodomys ordii	80.27	0.00e+00	969.00
IUUC-Dme-032186	Drosophila melanogaster	44.49	1.00e-101	363.00
IUUC-Ete-032368	Echinops telfairi	78.29	0.00e+00	984.00
IUUC-Eca-034325	Equus caballus	80.86	0.00e+00	968.00
IUUC-Fca-035537	Felis catus	82.49	0.00e+00	969.00
IUUC-Fal-037459	Ficedula albicollis	92.10	0.00e+00	1052.00
IUUC-Fso-038284	Fusarium solani	33.33	1.00e-08	54.70
IUUC-Gmo-039442	Gadus morhua	79.10	3.00e-100	358.00
IUUC-Gga-041071	Gallus gallus	98.83	0.00e+00	1100.00
IUUC-Gac-042483	Gasterosteus aculeatus	70.78	0.00e+00	879.00
IUUC-Ggo-044672	Gorilla gorilla	81.38	0.00e+00	998.00
IUUC-Hsa-045836	Homo sapiens	81.05	0.00e+00	971.00
IUUC-Itr-048588	Ictidomys tridecemlineatus	80.49	0.00e+00	1004.00
IUUC-Lch-050073	Latimeria chalumnae	76.73	0.00e+00	935.00
IUUC-Loc-052908	Lepisosteus oculatus	75.70	0.00e+00	919.00
IUUC-Laf-053519	Loxodonta africana	79.64	0.00e+00	998.00
IUUC-Mmr-061452	Microcebus murinus	85.41	0.00e+00	981.00
IUUC-Mdo-062412	Monodelphis domestica	82.35	0.00e+00	1006.00
IUUC-Mmu-063147	Mus musculus	80.65	0.00e+00	996.00
IUUC-Mpu-065929	Mustela putorius furo	81.22	0.00e+00	976.00
IUUC-Mlu-067899	Myotis lucifugus	78.78	0.00e+00	969.00
IUUC-Nle-070083	Nomascus leucogenys	81.22	0.00e+00	998.00
IUUC-Opr-070461	Ochotona princeps	77.40	0.00e+00	972.00
IUUC-Ont-072256	Oreochromis niloticus	74.24	0.00e+00	871.00
IUUC-Oan-073150	Ornithorhynchus anatinus	80.03	0.00e+00	905.00
IUUC-Ocu-073748	Oryctolagus cuniculus	78.85	0.00e+00	957.00
IUUC-Oga-088565	Otolemur garnettii	81.09	0.00e+00	998.00
IUUC-Oar-089432	Ovis aries	81.05	0.00e+00	1018.00
IUUC-Ptr-091422	Pan troglodytes	81.38	0.00e+00	997.00
IUUC-Pan-092331	Papio anubis	81.22	0.00e+00	998.00
IUUC-Psi-092933	Pelodiscus sinensis	90.19	0.00e+00	1013.00
IUUC-Pfo-097466	Poecilia formosa	72.98	0.00e+00	877.00
IUUC-Pab-098702	Pongo abelii	81.38	0.00e+00	997.00
IUUC-Pca-100125	Procavia capensis	79.46	0.00e+00	983.00
IUUC-Pva-102628	Pteropus vampyrus	81.99	0.00e+00	972.00
IUUC-Rno-104886	Rattus norvegicus	81.32	0.00e+00	1001.00
IUUC-Sce-106223	Saccharomyces cerevisiae	34.38	5.00e-07	47.00
IUUC-Sha-106702	Sarcophilus harrisii	82.30	0.00e+00	1002.00
IUUC-Ssc-116164	Sus scrofa	81.25	0.00e+00	1001.00
IUUC-Tgu-116829	Taeniopygia guttata	95.22	0.00e+00	1067.00
IUUC-Tru-118557	Takifugu rubripes	74.36	0.00e+00	844.00
IUUC-Tsy-119399	Tarsius syrichta	79.71	2.00e-177	614.00
IUUC-Tni-120006	Tetraodon nigroviridis	64.69	0.00e+00	704.00
IUUC-Tbe-127664	Tupaia belangeri	84.41	0.00e+00	963.00
IUUC-Ttr-129144	Tursiops truncatus	85.82	0.00e+00	1011.00
IUUC-Vpa-130226	Vicugna pacos	81.25	0.00e+00	1003.00
IUUC-Vvi-131278	Vitis vinifera	42.59	1.00e-10	58.90
IUUC-Xtr-132461	Xenopus tropicalis	73.29	0.00e+00	892.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence