iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048891

Ensembl Protein ID

ENSSTOP00000015964.1

UniProt Accession

I3MV19; I3MV19_ICTTR

Genbank Protein ID

ENSSTOP00000015964

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01068906

Gene Name

ZNRF4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000022733.1	ENSSTOT00000029892.1	ENSSTOP00000015964.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.50e-08	34.3	236	279

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdg..plvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiCl+++++g  +++lpC H++h  C+  w     s+  + +CP+C+
   Q: 236  CAICLDEYEEGdrLKILPCSHTYHCRCIGPW----FSQAARRSCPVCK 279
           ********55544999***************....99999*******7 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

AGAMGWPGPA LAALVLAVLL GPSRAVVRAV LEGNGSSVDF ADLPALFGVP LAPGGMRGYL 60
MEAKPANACQ PIEGPRPGNR SLGAIALIRR YDCTFDLKVL NAQRAGFEAA IVHNVRSDDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGGAGCCA TGGGGTGGCC TGGCCCGGCC CTGGCCGCGC TGGTCCTGGC CGTGCTGCTG 60
GGGCCCTCGC GGGCCGTGGT GCGCGCCGTG CTGGAGGGCA ACGGCAGCTC GGTGGACTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0732--Signal

Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF02225--PA
PF17123--zf-RING_11

SMART

SM00184--RING

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0008270--F:zinc ion binding
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001654	Ailuropoda melanoleuca	78.95	3.00e-125	441.00
IUUC-Bta-012572	Bos taurus	81.29	1.00e-116	412.00
IUUC-Cja-019445	Callithrix jacchus	75.66	2.00e-112	398.00
IUUC-Cfa-020828	Canis familiaris	84.93	2.00e-126	445.00
IUUC-Csa-023281	Chlorocebus sabaeus	81.68	2.00e-112	399.00
IUUC-Dor-030690	Dipodomys ordii	63.46	4.00e-62	230.00
IUUC-Ete-032610	Echinops telfairi	79.06	1.00e-120	426.00
IUUC-Ggo-045531	Gorilla gorilla	78.91	1.00e-113	402.00
IUUC-Hsa-045802	Homo sapiens	78.68	7.00e-111	393.00
IUUC-Laf-053469	Loxodonta africana	72.44	5.00e-124	436.00
IUUC-Mcc-054662	Macaca mulatta	78.32	2.00e-112	398.00
IUUC-Meu-056499	Macropus eugenii	61.65	7.00e-102	363.00
IUUC-Mdo-062468	Monodelphis domestica	59.21	7.00e-99	353.00
IUUC-Mmu-064409	Mus musculus	55.86	1.00e-61	229.00
IUUC-Mpu-066553	Mustela putorius furo	83.81	1.00e-124	439.00
IUUC-Oan-073710	Ornithorhynchus anatinus	49.23	3.00e-68	251.00
IUUC-Ptr-090842	Pan troglodytes	77.82	2.00e-112	399.00
IUUC-Pan-092278	Papio anubis	78.32	2.00e-112	398.00
IUUC-Pab-097537	Pongo abelii	82.03	2.00e-109	389.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence