iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050217

Ensembl Protein ID

ENSLACP00000012148.1

UniProt Accession

H3AR77; H3AR77_LATCH

Genbank Protein ID

ENSLACP00000012148

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

AFYH01154524

Gene Name

WHSC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000010693.1	ENSLACT00000012240.1	ENSLACP00000012148.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	5.10e-16	58.8	820	860

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +C vC +gg+    l++Ce C  +fHp+Cl+++    +p+ + w+C++Cr
   Q: 820  WCFVCSKGGS----LLCCESCPAAFHPDCLNIE----MPDGS-WYCNDCR 860
           8*********....*******************....9***8.******8 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MDLSAKGSSL LLKQELLNPI SMKPAAGILG SANGKTQNGE MNPDPAVLID KVAATLHEGV 60
ITKLNSHDAL PFLQADKLKN LTSRVLNGDS ETQESKLAAD AQEVMGTRTP PHNTPKKSGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGTTGAGT CAGTTATGAA TGAGCAATAA CCTCAAAAAA ATCATGGCAT ACATTTAAAA 60
AAAAAATTAC TGTATTTTAA ATGTAACGGT TCAGGCGTCA TGGAAATCTT CCTAACAGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR006560--AWS_dom
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51215--AWS
PS50118--HMG_BOX_2
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00505--HMG_box
PF00855--PWWP
PF00856--SET

SMART

SM00570--AWS
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0051216--P:cartilage development
GO:0048706--P:embryonic skeletal system development
GO:0010452--P:histone H3-K36 methylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002181	Ailuropoda melanoleuca	65.72	0.00e+00	1757.00
IUUC-Apl-003677	Anas platyrhynchos	68.94	0.00e+00	1826.00
IUUC-Aca-004278	Anolis carolinensis	69.88	0.00e+00	1318.00
IUUC-Ame-011932	Astyanax mexicanus	70.39	0.00e+00	1074.00
IUUC-Bta-012522	Bos taurus	64.91	0.00e+00	1666.00
IUUC-Bdi-014781	Brachypodium distachyon	30.86	2.00e-13	71.20
IUUC-Cja-018908	Callithrix jacchus	66.87	0.00e+00	1735.00
IUUC-Cfa-020894	Canis familiaris	66.22	0.00e+00	1771.00
IUUC-Cpo-021982	Cavia porcellus	66.47	0.00e+00	1729.00
IUUC-Csa-023807	Chlorocebus sabaeus	66.42	0.00e+00	1750.00
IUUC-Cho-024405	Choloepus hoffmanni	49.82	1.00e-138	487.00
IUUC-Csv-026298	Ciona savignyi	42.28	1.00e-60	226.00
IUUC-Dre-027492	Danio rerio	71.53	0.00e+00	1118.00
IUUC-Dno-030020	Dasypus novemcinctus	64.38	0.00e+00	1494.00
IUUC-Dor-031103	Dipodomys ordii	62.01	0.00e+00	1577.00
IUUC-Dme-032193	Drosophila melanogaster	37.42	3.00e-121	430.00
IUUC-Ete-032488	Echinops telfairi	61.93	0.00e+00	1569.00
IUUC-Eca-034066	Equus caballus	67.16	0.00e+00	1795.00
IUUC-Eeu-035199	Erinaceus europaeus	53.98	1.00e-162	567.00
IUUC-Fca-035434	Felis catus	66.23	0.00e+00	1505.00
IUUC-Fal-037113	Ficedula albicollis	66.81	0.00e+00	1830.00
IUUC-Gmo-039686	Gadus morhua	67.91	0.00e+00	1041.00
IUUC-Gga-040273	Gallus gallus	67.54	0.00e+00	1811.00
IUUC-Gac-042123	Gasterosteus aculeatus	49.59	0.00e+00	1250.00
IUUC-Ggo-044643	Gorilla gorilla	66.92	0.00e+00	1762.00
IUUC-Hsa-046380	Homo sapiens	66.54	0.00e+00	1744.00
IUUC-Itr-048658	Ictidomys tridecemlineatus	76.20	0.00e+00	1218.00
IUUC-Loc-052766	Lepisosteus oculatus	70.80	0.00e+00	1177.00
IUUC-Laf-053780	Loxodonta africana	66.04	0.00e+00	1761.00
IUUC-Mcc-054928	Macaca mulatta	67.01	0.00e+00	1777.00
IUUC-Mga-059576	Meleagris gallopavo	68.05	0.00e+00	1805.00
IUUC-Mmr-061045	Microcebus murinus	66.42	0.00e+00	1772.00
IUUC-Mdo-062576	Monodelphis domestica	67.08	0.00e+00	1797.00
IUUC-Mmu-063640	Mus musculus	67.20	0.00e+00	1746.00
IUUC-Mac-065303	Musa acuminata	29.22	2.00e-10	61.20
IUUC-Mpu-066512	Mustela putorius furo	66.92	0.00e+00	1759.00
IUUC-Nle-069896	Nomascus leucogenys	66.95	0.00e+00	1675.00
IUUC-Ont-072197	Oreochromis niloticus	74.78	0.00e+00	1068.00
IUUC-Oan-072724	Ornithorhynchus anatinus	68.99	0.00e+00	1176.00
IUUC-Ocu-074758	Oryctolagus cuniculus	66.47	0.00e+00	1711.00
IUUC-Obr-076122	Oryza brachyantha	31.55	2.00e-10	59.30
IUUC-Ogl-077641	Oryza glaberrima	28.32	6.00e-12	64.70
IUUC-Ogu-078030	Oryza glumaepatula	29.27	4.00e-14	72.00
IUUC-Oin-079557	Oryza indica	26.11	6.00e-12	64.70
IUUC-Olo-080702	Oryza longistaminata	41.01	6.00e-45	176.00
IUUC-Opu-083371	Oryza punctata	44.22	5.00e-46	179.00
IUUC-Osa-085353	Oryza sativa	28.32	5.00e-12	65.10
IUUC-Oga-088702	Otolemur garnettii	65.23	0.00e+00	1519.00
IUUC-Oar-089736	Ovis aries	61.94	0.00e+00	1493.00
IUUC-Ptr-091055	Pan troglodytes	66.54	0.00e+00	1744.00
IUUC-Pan-092752	Papio anubis	77.00	0.00e+00	1210.00
IUUC-Psi-093620	Pelodiscus sinensis	69.82	0.00e+00	1863.00
IUUC-Pfo-097464	Poecilia formosa	74.10	0.00e+00	1087.00
IUUC-Pab-098051	Pongo abelii	67.21	0.00e+00	1771.00
IUUC-Pop-099927	Populus trichocarpa	28.93	4.00e-11	63.50
IUUC-Pca-100273	Procavia capensis	67.05	0.00e+00	1734.00
IUUC-Pva-102473	Pteropus vampyrus	61.35	0.00e+00	1484.00
IUUC-Rno-105056	Rattus norvegicus	67.42	0.00e+00	1766.00
IUUC-Sha-107494	Sarcophilus harrisii	67.86	0.00e+00	1786.00
IUUC-Sar-113310	Sorex araneus	68.67	0.00e+00	1395.00
IUUC-Sbi-114581	Sorghum bicolor	34.26	3.00e-11	62.40
IUUC-Ssc-116344	Sus scrofa	65.03	0.00e+00	1671.00
IUUC-Tgu-116786	Taeniopygia guttata	68.59	0.00e+00	1825.00
IUUC-Tru-117638	Takifugu rubripes	50.26	0.00e+00	1270.00
IUUC-Tsy-118937	Tarsius syrichta	74.11	0.00e+00	1251.00
IUUC-Tbe-127291	Tupaia belangeri	69.23	0.00e+00	1223.00
IUUC-Ttr-129017	Tursiops truncatus	58.96	0.00e+00	1230.00
IUUC-Xtr-132673	Xenopus tropicalis	62.63	0.00e+00	1635.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence