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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Dme-032172
UUCD1 version UUC-DrM-00108
Ensembl Protein ID FBpp0080596
UniProt Accession Q04652; F0JAF0; Q04653; Q86PA7; Q9VJA2; KELC_DROME
Genbank Protein ID AAA53471.1; AAA53472.2; AAF53651.1; AAN11182.3; ADZ05867.1
Protein Name Ring canal kelch protein; Kelch short protein
Genbank Nucleotide ID L08483; L08483; AE014134; AE014134; BT003250
Gene Name kel; CG7210
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0001301 FBtr0081043 FBpp0080596
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IIDiRefIndexPINAMentha
Post-translational Modifications (PTMs)
dbPAFdbPTMPhospho.ELMUniProt
Protein Expression/Proteomics
GPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
E3 adaptor/Cullin RING/BCR/BTB_3-box BTB_3-box 23487316
Classification
Family E-value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB 6.30e-18 64.9 157 223
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box 3.50e-12 45.3 256 286
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB
   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dvilv +++e++ah+ vLa++S++Fya+f + +ees+ + +++++ v++ +++ l++++Yt +++ ne
   Q: 157  CDVILVADDVEIHAHRMVLASCSPYFYAMF-TSFEESR-QARITLQSVDARALELLIDYVYTATVEVNE 223
           8*****************************.56****9.*************************99886 PP
   

   E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box
   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
           +Nclgi+ fAd++ c +L  +a+++i++hF+
   Q: 256  SNCLGIREFADIHACVELLNYAETYIEQHFN 286
           8*****************************6 PP
   
Organism Drosophila melanogaster
Functional Description
(View)

Functional Description


     Component of ring canals that regulates the flow of cytoplasm between cells. May be involved in the regulation of cytoplasm flow from nurse cells to the oocyte during oogenesis. Binds actin.
 Component of ring canals that regulates the flow of cytoplasm between cells. May be involved in the regulation of cytoplasm flow from nurse cells to the oocyte during oogenesis. Binds actin.
Protein Sequence
(Fasta)
MIALSALLTK YTIGIMSNLS NGNSNNNNQQ QQQQQQGQNP QQPAQNEGGA GAEFVAPPPG 60
LGAAVGVAAM QQRNRLLQQQ QQQHHHHQNP AAEGSGLERG SCLLRYASQN SLDESSQKHV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dme-032172|E3,BTB_3-box|Drosophila melanogaster
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TCGCTAGTGG TAACTTGCGA CCAACCCGAG GCTGGTCACA CTGCTCTGGT CGCGTCCAAA 60
AAGTGTACAA TTTTTCACCA CCTCGGTTTG TTTTTTCGGA CCAGGCGAGG CACCTTCGAT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dme-032172|E3,BTB_3-box|Drosophila melanogaster
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0009--Actin-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0217--Developmental protein
KW-0221--Differentiation
KW-0880--Kelch repeat
KW-0896--Oogenesis
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0712--Selenocysteine
Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ
IPR015943--WD40/YVTN_repeat-like_dom
PROSITE

PS50097--BTB
Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1
SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch
Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0005856--C:cytoskeleton
GO:0035324--C:female germline ring canal
GO:0035183--C:female germline ring canal inner rim
GO:0045172--C:germline ring canal
GO:0003779--F:actin binding
GO:0030036--P:actin cytoskeleton organization
GO:0007349--P:cellularization
GO:0007301--P:female germline ring canal formation
GO:0030717--P:karyosome formation
GO:0048477--P:oogenesis
GO:0007297--P:ovarian follicle cell migration
GO:0030723--P:ovarian fusome organization
GO:0007300--P:ovarian nurse cell to oocyte transport
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
KEGG dme:Dmel_CG7210
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002378 Ailuropoda melanoleuca 61.90 0.00e+00 699.00
IUUC-Apl-003260 Anas platyrhynchos 61.54 0.00e+00 701.00
IUUC-Aca-005143 Anolis carolinensis 59.93 0.00e+00 707.00
IUUC-Ame-010670 Astyanax mexicanus 60.43 0.00e+00 670.00
IUUC-Bta-013354 Bos taurus 58.77 0.00e+00 695.00
IUUC-Bci-013669 Botrytis cinerea 39.47 1.00e-07 53.10
IUUC-Bdi-014143 Brachypodium distachyon 33.56 3.00e-43 169.00
IUUC-Cel-018136 Caenorhabditis elegans 43.44 2.00e-129 455.00
IUUC-Cja-018942 Callithrix jacchus 61.90 0.00e+00 699.00
IUUC-Cfa-020886 Canis familiaris 62.08 0.00e+00 701.00
IUUC-Cpo-022543 Cavia porcellus 62.08 0.00e+00 701.00
IUUC-Csa-023088 Chlorocebus sabaeus 62.08 0.00e+00 701.00
IUUC-Csv-026032 Ciona savignyi 54.25 5.00e-170 590.00
IUUC-Dre-028082 Danio rerio 60.47 0.00e+00 689.00
IUUC-Dno-029873 Dasypus novemcinctus 61.10 0.00e+00 689.00
IUUC-Dor-030156 Dipodomys ordii 49.37 1.00e-155 542.00
IUUC-Dse-031229 Dothistroma septosporum 29.25 3.00e-08 50.80
IUUC-Ete-033064 Echinops telfairi 51.59 3.00e-140 491.00
IUUC-Eca-033798 Equus caballus 61.72 0.00e+00 697.00
IUUC-Eeu-034824 Erinaceus europaeus 58.75 8.00e-179 619.00
IUUC-Fca-036455 Felis catus 62.08 0.00e+00 701.00
IUUC-Fal-037293 Ficedula albicollis 61.12 0.00e+00 692.00
IUUC-Gmo-038811 Gadus morhua 59.03 0.00e+00 627.00
IUUC-Gga-040805 Gallus gallus 61.72 0.00e+00 701.00
IUUC-Gac-041979 Gasterosteus aculeatus 61.00 0.00e+00 632.00
IUUC-Ggo-045485 Gorilla gorilla 58.60 0.00e+00 688.00
IUUC-Hsa-046265 Homo sapiens 62.08 0.00e+00 701.00
IUUC-Itr-048605 Ictidomys tridecemlineatus 60.47 0.00e+00 695.00
IUUC-Lch-050246 Latimeria chalumnae 56.29 0.00e+00 655.00
IUUC-Loc-052780 Lepisosteus oculatus 62.08 0.00e+00 704.00
IUUC-Laf-053800 Loxodonta africana 59.60 0.00e+00 699.00
IUUC-Mcc-055732 Macaca mulatta 61.47 0.00e+00 689.00
IUUC-Meu-056011 Macropus eugenii 62.92 0.00e+00 683.00
IUUC-Mga-059994 Meleagris gallopavo 58.71 7.00e-176 609.00
IUUC-Mmr-061067 Microcebus murinus 61.71 0.00e+00 687.00
IUUC-Mdo-062977 Monodelphis domestica 62.25 0.00e+00 699.00
IUUC-Mmu-064035 Mus musculus 61.71 0.00e+00 687.00
IUUC-Mpu-066726 Mustela putorius furo 62.08 0.00e+00 700.00
IUUC-Mlu-067020 Myotis lucifugus 62.08 0.00e+00 701.00
IUUC-Nle-069456 Nomascus leucogenys 62.08 0.00e+00 701.00
IUUC-Opr-071130 Ochotona princeps 55.46 9.00e-174 602.00
IUUC-Ont-072219 Oreochromis niloticus 61.36 0.00e+00 669.00
IUUC-Oan-073699 Ornithorhynchus anatinus 61.66 6.00e-180 622.00
IUUC-Ocu-074045 Oryctolagus cuniculus 60.51 0.00e+00 702.00
IUUC-Ogl-077595 Oryza glaberrima 32.88 4.00e-36 145.00
IUUC-Oin-079973 Oryza indica 32.53 1.00e-35 144.00
IUUC-Olo-080536 Oryza longistaminata 33.20 1.00e-33 138.00
IUUC-Osa-085891 Oryza sativa 32.88 1.00e-36 147.00
IUUC-Ola-086853 Oryzias latipes 59.08 0.00e+00 658.00
IUUC-Oga-088494 Otolemur garnettii 62.08 0.00e+00 701.00
IUUC-Oar-089645 Ovis aries 61.72 0.00e+00 697.00
IUUC-Ptr-091063 Pan troglodytes 62.08 0.00e+00 700.00
IUUC-Pan-091705 Papio anubis 58.90 0.00e+00 697.00
IUUC-Psi-093946 Pelodiscus sinensis 60.25 0.00e+00 697.00
IUUC-Pma-094177 Petromyzon marinus 61.46 0.00e+00 646.00
IUUC-Pno-095143 Phaeosphaeria nodorum 23.86 1.00e-13 70.10
IUUC-Ppa-095249 Physcomitrella patens 31.31 4.00e-16 78.60
IUUC-Pfo-096817 Poecilia formosa 60.47 0.00e+00 679.00
IUUC-Pab-097768 Pongo abelii 62.08 0.00e+00 701.00
IUUC-Pca-100607 Procavia capensis 54.93 4.00e-130 457.00
IUUC-Pva-102218 Pteropus vampyrus 58.68 0.00e+00 649.00
IUUC-Pgr-103359 Puccinia graminis 26.44 1.70e-02 33.50
IUUC-Pyt-104553 Pyrenophora triticirepentis 29.89 4.00e-06 45.40
IUUC-Rno-105250 Rattus norvegicus 61.90 0.00e+00 698.00
IUUC-Ssl-108429 Sclerotinia sclerotiorum 27.81 7.00e-06 43.90
IUUC-Sar-113249 Sorex araneus 61.45 0.00e+00 681.00
IUUC-Ssc-115423 Sus scrofa 61.72 0.00e+00 697.00
IUUC-Tgu-117050 Taeniopygia guttata 60.36 0.00e+00 687.00
IUUC-Tru-118239 Takifugu rubripes 60.66 0.00e+00 702.00
IUUC-Tsy-119377 Tarsius syrichta 52.42 5.00e-172 596.00
IUUC-Tni-120122 Tetraodon nigroviridis 61.41 0.00e+00 640.00
IUUC-Tae-124075 Triticum aestivum 29.82 1.00e-39 157.00
IUUC-Vpa-130707 Vicugna pacos 59.66 3.00e-161 560.00
IUUC-Xtr-132035 Xenopus tropicalis 61.32 0.00e+00 718.00
Created Date 25-Jun-2017

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