iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091412

UUCD1 version

UUC-PaT-00261

Ensembl Protein ID

ENSPTRP00000011503.5

UniProt Accession

H2Q8Y3; H2Q8Y3_PANTR

Genbank Protein ID

JAA02835.1; JAA19609.1; JAA23613.1

Protein Name

TNF receptor-associated factor 3

Genbank Nucleotide ID

AACZ03097218; GABF01002536; GABD01009487

Gene Name

TRAF3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000006746.5	ENSPTRT00000012430.5	ENSPTRP00000011503.5

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	99.82	0.00e+00	1181.00	IUUC-Hsa-046957

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MESSKKMDSP GALQTNPPLK LHTDRSAGTP VFVPEQGGYK EKFVKTVEDK YKCEKCHLVL 60
CSPKQTECGH RFCESCMAAL LSSSSPKCTA CQESIVKDKV FKDNCCKREI LALQIYCRNE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGACAGAAC TCCTCTTTCC TAAAATGGAG TCGAGTAAAA AGATGGACTC TCCTGGCGCG 60
CTGCAGACTA ACCCGCCGCT AAAGCTGCAC ACTGACCGCA GTGCTGGGAC GCCAGTTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0675--Receptor
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027128--TRAF3
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF02176--zf-TRAF

SMART

SM00061--MATH

Gene Ontology

GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0042981--P:regulation of apoptotic process
GO:0050688--P:regulation of defense response to virus
GO:0032648--P:regulation of interferon-beta production
GO:0030162--P:regulation of proteolysis
GO:0008063--P:Toll signaling pathway
GO:0002224--P:toll-like receptor signaling pathway
GO:0033209--P:tumor necrosis factor-mediated signaling pathway

KEGG

ptr:453178

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002362	Ailuropoda melanoleuca	96.13	0.00e+00	1140.00
IUUC-Apl-004189	Anas platyrhynchos	88.20	0.00e+00	1059.00
IUUC-Aca-004540	Anolis carolinensis	85.21	0.00e+00	1025.00
IUUC-Ate-010296	Aspergillus terreus	26.70	2.00e-18	86.70
IUUC-Ame-010645	Astyanax mexicanus	57.96	0.00e+00	652.00
IUUC-Bta-013140	Bos taurus	94.72	0.00e+00	1127.00
IUUC-Cja-019436	Callithrix jacchus	98.77	0.00e+00	1170.00
IUUC-Cfa-021072	Canis familiaris	96.30	0.00e+00	1145.00
IUUC-Cpo-022472	Cavia porcellus	95.60	0.00e+00	1134.00
IUUC-Csa-024217	Chlorocebus sabaeus	99.12	0.00e+00	1173.00
IUUC-Cho-025066	Choloepus hoffmanni	83.27	0.00e+00	838.00
IUUC-Cin-025234	Ciona intestinalis	29.57	2.00e-54	206.00
IUUC-Csv-026078	Ciona savignyi	68.54	7.00e-80	289.00
IUUC-Dre-028208	Danio rerio	55.23	4.00e-177	614.00
IUUC-Dno-028868	Dasypus novemcinctus	94.54	0.00e+00	1130.00
IUUC-Dor-031056	Dipodomys ordii	97.33	0.00e+00	987.00
IUUC-Ete-033005	Echinops telfairi	82.05	0.00e+00	789.00
IUUC-Eca-033717	Equus caballus	97.01	0.00e+00	1153.00
IUUC-Eeu-035172	Erinaceus europaeus	84.13	0.00e+00	633.00
IUUC-Fca-035688	Felis catus	95.96	0.00e+00	1137.00
IUUC-Fal-037176	Ficedula albicollis	88.20	0.00e+00	1060.00
IUUC-Gmo-038931	Gadus morhua	55.87	2.00e-169	588.00
IUUC-Gac-042019	Gasterosteus aculeatus	56.94	2.00e-178	619.00
IUUC-Ggo-044424	Gorilla gorilla	99.82	0.00e+00	1180.00
IUUC-Hsa-046957	Homo sapiens	99.82	0.00e+00	1181.00
IUUC-Itr-048352	Ictidomys tridecemlineatus	96.13	0.00e+00	1133.00
IUUC-Lch-050680	Latimeria chalumnae	68.49	0.00e+00	833.00
IUUC-Loc-052093	Lepisosteus oculatus	56.92	0.00e+00	689.00
IUUC-Laf-054573	Loxodonta africana	87.50	0.00e+00	1022.00
IUUC-Mcc-055049	Macaca mulatta	98.77	0.00e+00	1167.00
IUUC-Mga-059244	Meleagris gallopavo	87.50	0.00e+00	1054.00
IUUC-Mmr-061469	Microcebus murinus	97.36	0.00e+00	1151.00
IUUC-Mdo-063049	Monodelphis domestica	92.08	0.00e+00	1097.00
IUUC-Mmu-063763	Mus musculus	96.30	0.00e+00	1138.00
IUUC-Mpu-065956	Mustela putorius furo	94.20	0.00e+00	1090.00
IUUC-Mlu-067482	Myotis lucifugus	94.72	0.00e+00	1124.00
IUUC-Nle-069941	Nomascus leucogenys	99.30	0.00e+00	1175.00
IUUC-Opr-071027	Ochotona princeps	81.69	0.00e+00	910.00
IUUC-Ont-071914	Oreochromis niloticus	58.10	0.00e+00	659.00
IUUC-Oan-072802	Ornithorhynchus anatinus	91.20	0.00e+00	1085.00
IUUC-Ocu-074075	Oryctolagus cuniculus	96.65	0.00e+00	1143.00
IUUC-Oga-088149	Otolemur garnettii	97.01	0.00e+00	1153.00
IUUC-Oar-089922	Ovis aries	90.73	0.00e+00	1069.00
IUUC-Pan-092789	Papio anubis	99.12	0.00e+00	1173.00
IUUC-Psi-093603	Pelodiscus sinensis	85.34	0.00e+00	1029.00
IUUC-Pma-094463	Petromyzon marinus	48.85	5.00e-140	490.00
IUUC-Pfo-096518	Poecilia formosa	55.61	0.00e+00	644.00
IUUC-Pab-097664	Pongo abelii	99.82	0.00e+00	1180.00
IUUC-Pca-100821	Procavia capensis	86.01	0.00e+00	858.00
IUUC-Pva-103201	Pteropus vampyrus	83.63	0.00e+00	977.00
IUUC-Rno-105505	Rattus norvegicus	95.25	0.00e+00	1128.00
IUUC-Sha-107416	Sarcophilus harrisii	92.43	0.00e+00	1098.00
IUUC-Sar-113438	Sorex araneus	93.55	4.00e-100	357.00
IUUC-Ssc-115351	Sus scrofa	95.60	0.00e+00	1131.00
IUUC-Tgu-116608	Taeniopygia guttata	90.16	0.00e+00	1053.00
IUUC-Tru-117964	Takifugu rubripes	57.54	0.00e+00	626.00
IUUC-Tni-120211	Tetraodon nigroviridis	56.54	0.00e+00	636.00
IUUC-Tur-126245	Triticum urartu	24.60	1.00e-06	47.80
IUUC-Tbe-127700	Tupaia belangeri	79.38	6.00e-143	501.00
IUUC-Ttr-128450	Tursiops truncatus	90.00	3.00e-172	597.00
IUUC-Vda-129938	Verticillium dahliae	25.59	7.00e-21	95.50
IUUC-Vpa-130074	Vicugna pacos	97.73	0.00e+00	894.00
IUUC-Xtr-132563	Xenopus tropicalis	78.52	0.00e+00	955.00
IUUC-Xma-133628	Xiphophorus maculatus	55.61	0.00e+00	643.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence