iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054064

UUCD1 version

UUC-LoA-00941

Ensembl Protein ID

ENSLAFP00000028881.1

UniProt Accession

G3UM22; G3UM22_LOXAF

Protein Name

Uncharacterized protein

Gene Name

RNF152

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000007283.3	ENSLAFT00000007283.3	ENSLAFP00000028881.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.10e-06	27.6	12	55

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC++ +  ++ p++l+C+H+ +  Clq++    + s+k  rCP+Cr
   Q: 12   CQICFNYYspRRRPKLLDCKHTCCSVCLQQM----RTSQKDVRCPWCR 55
           9*****8888555***************999....99**********8 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

METLSQDSLL ECQICFNYYS PRRRPKLLDC KHTCCSVCLQ QMRTSQKDVR CPWCRGITKL 60
PPGFSVSQLP DDPEVLAVIA IPHTSEHTPV FIKLPSNGCY MLPLPISKER TLLPGDMGCR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGACGC TCTCCCAGGA TTCTCTGCTG GAATGCCAGA TCTGCTTCAA TTATTACAGC 60
CCACGGCGCA GGCCCAAGCT GCTGGACTGC AAGCACACCT GCTGCTCGGT GTGCCTCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR033609--RNF152
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF14634--zf-RING_5

SMART

SM00184--RING

Gene Ontology

GO:0031301--C:integral component of organelle membrane
GO:0005765--C:lysosomal membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0034198--P:cellular response to amino acid starvation
GO:1904262--P:negative regulation of TORC1 signaling
GO:0010508--P:positive regulation of autophagy
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination

KEGG

lav:100676398

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001569	Ailuropoda melanoleuca	94.58	6.00e-112	395.00
IUUC-Apl-003754	Anas platyrhynchos	43.53	9.00e-10	57.00
IUUC-Aca-004700	Anolis carolinensis	93.60	6.00e-111	392.00
IUUC-Ame-011661	Astyanax mexicanus	55.88	1.00e-50	192.00
IUUC-Cja-019799	Callithrix jacchus	96.55	2.00e-106	377.00
IUUC-Cfa-020144	Canis familiaris	93.60	3.00e-99	353.00
IUUC-Cpo-021632	Cavia porcellus	97.04	2.00e-113	400.00
IUUC-Csa-023858	Chlorocebus sabaeus	97.04	8.00e-107	379.00
IUUC-Cho-024669	Choloepus hoffmanni	95.20	8.00e-69	251.00
IUUC-Dre-027881	Danio rerio	59.11	3.00e-58	217.00
IUUC-Dno-029695	Dasypus novemcinctus	91.13	2.00e-98	350.00
IUUC-Dor-030795	Dipodomys ordii	96.55	2.00e-103	367.00
IUUC-Eca-033412	Equus caballus	97.04	1.00e-106	378.00
IUUC-Eeu-034580	Erinaceus europaeus	43.06	9.00e-09	53.50
IUUC-Fca-036256	Felis catus	96.06	3.00e-106	377.00
IUUC-Fal-036943	Ficedula albicollis	92.12	2.00e-102	364.00
IUUC-Gga-040800	Gallus gallus	93.60	4.00e-111	393.00
IUUC-Gac-042045	Gasterosteus aculeatus	42.86	5.00e-10	57.80
IUUC-Ggo-045477	Gorilla gorilla	97.04	2.00e-114	404.00
IUUC-Hsa-046568	Homo sapiens	97.04	2.00e-114	404.00
IUUC-Itr-049081	Ictidomys tridecemlineatus	95.57	1.00e-111	394.00
IUUC-Lch-049770	Latimeria chalumnae	85.22	3.00e-96	343.00
IUUC-Loc-052353	Lepisosteus oculatus	86.09	9.00e-60	221.00
IUUC-Mcc-054875	Macaca mulatta	97.04	8.00e-107	379.00
IUUC-Meu-056370	Macropus eugenii	94.61	5.00e-111	392.00
IUUC-Mga-059847	Meleagris gallopavo	93.60	5.00e-111	392.00
IUUC-Mmr-061042	Microcebus murinus	96.55	3.00e-113	400.00
IUUC-Mdo-063047	Monodelphis domestica	93.63	2.00e-109	387.00
IUUC-Mmu-064228	Mus musculus	97.04	3.00e-109	387.00
IUUC-Mlu-067736	Myotis lucifugus	95.57	3.00e-100	357.00
IUUC-Nle-069697	Nomascus leucogenys	97.04	8.00e-107	379.00
IUUC-Ont-072208	Oreochromis niloticus	74.65	6.00e-86	309.00
IUUC-Oan-073566	Ornithorhynchus anatinus	84.31	1.00e-89	322.00
IUUC-Ocu-074089	Oryctolagus cuniculus	95.07	2.00e-101	360.00
IUUC-Obr-076611	Oryza brachyantha	40.82	2.10e-02	33.50
IUUC-Ola-087210	Oryzias latipes	71.36	2.00e-76	278.00
IUUC-Oga-088395	Otolemur garnettii	97.04	3.00e-104	370.00
IUUC-Oar-090382	Ovis aries	95.83	3.00e-21	92.80
IUUC-Ptr-091480	Pan troglodytes	97.04	2.00e-114	404.00
IUUC-Pan-091715	Papio anubis	97.04	8.00e-107	379.00
IUUC-Psi-093465	Pelodiscus sinensis	93.60	1.00e-110	391.00
IUUC-Pfo-097259	Poecilia formosa	75.47	7.00e-90	322.00
IUUC-Pab-097769	Pongo abelii	97.04	2.00e-114	404.00
IUUC-Pca-100657	Procavia capensis	98.03	9.00e-115	405.00
IUUC-Pva-102521	Pteropus vampyrus	96.06	2.00e-113	401.00
IUUC-Rno-105521	Rattus norvegicus	96.55	2.00e-113	400.00
IUUC-Sha-107197	Sarcophilus harrisii	95.10	3.00e-111	393.00
IUUC-Ssc-116239	Sus scrofa	96.55	6.00e-114	402.00
IUUC-Tgu-117096	Taeniopygia guttata	44.71	2.00e-10	58.90
IUUC-Tru-118315	Takifugu rubripes	74.41	2.00e-82	297.00
IUUC-Tsy-119645	Tarsius syrichta	97.54	1.00e-114	404.00
IUUC-Tni-119835	Tetraodon nigroviridis	74.88	1.00e-87	315.00
IUUC-Tbe-127264	Tupaia belangeri	96.55	3.00e-109	386.00
IUUC-Ttr-128749	Tursiops truncatus	96.06	2.00e-108	384.00
IUUC-Vpa-130808	Vicugna pacos	97.04	2.00e-109	387.00
IUUC-Xtr-131837	Xenopus tropicalis	43.42	1.00e-09	56.20

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence