iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053866

Ensembl Protein ID

ENSLAFP00000014019.3

UniProt Accession

G3THH6; G3THH6_LOXAF

Protein Name

Uncharacterized protein

Gene Name

CTTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000016700.3	ENSLAFT00000016705.3	ENSLAFP00000014019.3
ENSLAFG00000016700.3	ENSLAFT00000030313.1	ENSLAFP00000026395.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.20e-13	48.3	498	547

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           ++lydy+a+ dde ++   d+++ i  e  d gW++g    +g+ GlfP+n+ve
   Q: 498  IALYDYQAAGDDEISFDPDDIITNI--EMIDDGWWRG--VCKGRYGLFPANYVE 547
           79***********************..9*********..7************97 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MWKASAGHAV SIAQDDGGAD DWETDPDFVN DVSEKEQRWG AKTVQGSGHQ EHINIHKLRE 60
NVFQEHQTLK EKELETGPRA SHGYGGKFGV EQDRMDKSAV GHEYQSKLSK HCSQVDSVRG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGGAAAG CCTCTGCGGG CCATGCTGTG TCCATCGCCC AGGACGATGG GGGTGCAGAC 60
GACTGGGAAA CGGACCCCGA TTTTGTGGTA TGAGTCGCCA GTCTGTTTTT CAGTTTTCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015503--Cortactin
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005884--C:actin filament
GO:0030863--C:cortical cytoskeleton
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0030027--C:lamellipodium
GO:1990023--C:mitotic spindle midzone
GO:0002102--C:podosome
GO:0001726--C:ruffle
GO:0008076--C:voltage-gated potassium channel complex
GO:0030041--P:actin filament polymerization
GO:0097062--P:dendritic spine maintenance
GO:0006886--P:intracellular protein transport
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0030838--P:positive regulation of actin filament polymerization
GO:0045987--P:positive regulation of smooth muscle contraction
GO:1903146--P:regulation of mitophagy
GO:0006930--P:substrate-dependent cell migration, cell extension

KEGG

lav:100661591

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002064	Ailuropoda melanoleuca	88.75	0.00e+00	902.00
IUUC-Apl-003745	Anas platyrhynchos	84.68	0.00e+00	770.00
IUUC-Aca-004438	Anolis carolinensis	81.17	0.00e+00	867.00
IUUC-Bgr-012041	Blumeria graminis	57.89	6.00e-16	79.30
IUUC-Bta-013563	Bos taurus	88.18	0.00e+00	870.00
IUUC-Cfa-020718	Canis familiaris	85.90	0.00e+00	901.00
IUUC-Cpo-022303	Cavia porcellus	88.20	0.00e+00	951.00
IUUC-Csa-023431	Chlorocebus sabaeus	90.40	0.00e+00	902.00
IUUC-Cin-025677	Ciona intestinalis	62.24	1.00e-119	423.00
IUUC-Csv-026140	Ciona savignyi	64.33	1.00e-108	387.00
IUUC-Dre-028012	Danio rerio	65.27	1.00e-180	625.00
IUUC-Dno-029332	Dasypus novemcinctus	81.88	0.00e+00	764.00
IUUC-Dme-031931	Drosophila melanogaster	62.17	3.00e-73	269.00
IUUC-Eca-033801	Equus caballus	90.40	0.00e+00	903.00
IUUC-Fca-035633	Felis catus	87.17	0.00e+00	741.00
IUUC-Fal-036775	Ficedula albicollis	83.78	0.00e+00	765.00
IUUC-Gmo-038507	Gadus morhua	70.69	2.00e-20	93.20
IUUC-Gga-040568	Gallus gallus	84.68	0.00e+00	798.00
IUUC-Gac-042253	Gasterosteus aculeatus	56.91	1.00e-115	410.00
IUUC-Hsa-046818	Homo sapiens	90.76	0.00e+00	902.00
IUUC-Itr-048833	Ictidomys tridecemlineatus	86.08	0.00e+00	835.00
IUUC-Lch-050199	Latimeria chalumnae	71.67	7.00e-146	510.00
IUUC-Loc-052855	Lepisosteus oculatus	75.63	8.00e-153	533.00
IUUC-Mcc-055515	Macaca mulatta	90.22	0.00e+00	898.00
IUUC-Mga-059791	Meleagris gallopavo	84.03	0.00e+00	796.00
IUUC-Mmr-061147	Microcebus murinus	91.14	0.00e+00	860.00
IUUC-Mdo-062660	Monodelphis domestica	60.61	2.00e-174	606.00
IUUC-Mmu-064023	Mus musculus	88.57	0.00e+00	879.00
IUUC-Mpu-065867	Mustela putorius furo	79.45	0.00e+00	771.00
IUUC-Mlu-067704	Myotis lucifugus	83.36	0.00e+00	775.00
IUUC-Ont-071873	Oreochromis niloticus	80.11	5.00e-166	577.00
IUUC-Oan-073528	Ornithorhynchus anatinus	83.83	4.00e-160	557.00
IUUC-Oga-088028	Otolemur garnettii	90.04	0.00e+00	891.00
IUUC-Oar-090203	Ovis aries	87.57	0.00e+00	798.00
IUUC-Pan-092594	Papio anubis	85.90	0.00e+00	836.00
IUUC-Psi-093389	Pelodiscus sinensis	83.92	0.00e+00	810.00
IUUC-Pma-094161	Petromyzon marinus	46.85	1.00e-85	310.00
IUUC-Pfo-096269	Poecilia formosa	60.27	9.00e-107	380.00
IUUC-Pab-097913	Pongo abelii	83.15	0.00e+00	791.00
IUUC-Rno-105489	Rattus norvegicus	87.75	0.00e+00	867.00
IUUC-Sce-106228	Saccharomyces cerevisiae	50.00	8.00e-07	48.50
IUUC-Sha-107308	Sarcophilus harrisii	70.92	0.00e+00	678.00
IUUC-Sja-107956	Schizosaccharomyces japonicus	55.17	1.00e-14	75.10
IUUC-Tgu-117049	Taeniopygia guttata	77.58	0.00e+00	698.00
IUUC-Tru-118718	Takifugu rubripes	76.82	1.00e-158	553.00
IUUC-Tni-120535	Tetraodon nigroviridis	58.08	9.00e-163	566.00
IUUC-Vda-129766	Verticillium dahliae	57.89	1.00e-13	72.00
IUUC-Xtr-131797	Xenopus tropicalis	66.09	0.00e+00	660.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence