iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093449

Ensembl Protein ID

ENSPSIP00000016158.1

UniProt Accession

K7G797; K7G797_PELSI

Genbank Protein ID

ENSPSIP00000016158

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01164263

Gene Name

FBXW5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000014416.1	ENSPSIT00000016234.1	ENSPSIP00000016158.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.10e-14	51.6	91	120

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWD 29
           H+d v  l+f  s+ l++s+s D+t+k+W+
   Q: 91   HNDQVLHLSFshSGYLFASCSKDCTVKIWN 120
           9*********9555889************9 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MDVVGSPLLP DSILYEIFLY LDHIDVLSVG LVCQQWHAVA RDEFLWKELF YRYYRVSREV 60
PRHPAAVSWY EEFQRLYDTI PCVEVQTLRE HNDQVLHLSF SHSGYLFASC SKDCTVKIWN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNCGCT ATCGCCCCGA 60
GACAAAGCTC CAGACGCGTT TCACTTGCTG GTCTCAGCCG CGGCCCCTTG CCTTTGAAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0016567--P:protein ubiquitination
GO:0010824--P:regulation of centrosome duplication
GO:0007088--P:regulation of mitotic nuclear division
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001942	Ailuropoda melanoleuca	72.96	0.00e+00	861.00
IUUC-Apl-003274	Anas platyrhynchos	87.06	0.00e+00	873.00
IUUC-Aca-004626	Anolis carolinensis	55.02	9.00e-94	336.00
IUUC-Ame-011823	Astyanax mexicanus	62.63	0.00e+00	648.00
IUUC-Bta-012523	Bos taurus	73.98	0.00e+00	870.00
IUUC-Cja-018729	Callithrix jacchus	75.72	0.00e+00	897.00
IUUC-Cfa-020303	Canis familiaris	74.15	0.00e+00	891.00
IUUC-Cpo-022134	Cavia porcellus	75.17	0.00e+00	894.00
IUUC-Csa-023253	Chlorocebus sabaeus	76.19	0.00e+00	915.00
IUUC-Cin-025742	Ciona intestinalis	33.79	1.00e-82	300.00
IUUC-Dre-027511	Danio rerio	69.18	0.00e+00	767.00
IUUC-Dno-029044	Dasypus novemcinctus	74.15	0.00e+00	890.00
IUUC-Dor-030565	Dipodomys ordii	75.04	0.00e+00	882.00
IUUC-Dme-031713	Drosophila melanogaster	43.64	2.00e-132	466.00
IUUC-Eca-033709	Equus caballus	76.71	0.00e+00	873.00
IUUC-Eeu-035093	Erinaceus europaeus	82.95	8.00e-85	307.00
IUUC-Fca-035674	Felis catus	75.38	0.00e+00	881.00
IUUC-Fal-037104	Ficedula albicollis	83.50	0.00e+00	930.00
IUUC-Gmo-039041	Gadus morhua	62.76	0.00e+00	674.00
IUUC-Gga-041230	Gallus gallus	85.91	0.00e+00	1005.00
IUUC-Gac-042594	Gasterosteus aculeatus	61.53	0.00e+00	672.00
IUUC-Ggo-044486	Gorilla gorilla	75.85	0.00e+00	885.00
IUUC-Hsa-045701	Homo sapiens	75.51	0.00e+00	884.00
IUUC-Itr-048811	Ictidomys tridecemlineatus	75.51	0.00e+00	898.00
IUUC-Kpa-049204	Komagataella pastoris	32.39	2.00e-06	47.80
IUUC-Lch-050058	Latimeria chalumnae	73.89	0.00e+00	890.00
IUUC-Loc-052525	Lepisosteus oculatus	71.65	0.00e+00	762.00
IUUC-Laf-054120	Loxodonta africana	75.72	0.00e+00	905.00
IUUC-Mcc-054915	Macaca mulatta	75.85	0.00e+00	894.00
IUUC-Meu-056715	Macropus eugenii	74.70	0.00e+00	888.00
IUUC-Mga-059831	Meleagris gallopavo	85.98	0.00e+00	892.00
IUUC-Mmr-060655	Microcebus murinus	75.00	0.00e+00	889.00
IUUC-Mdo-062641	Monodelphis domestica	80.68	0.00e+00	947.00
IUUC-Mmu-063471	Mus musculus	73.94	0.00e+00	880.00
IUUC-Mpu-066586	Mustela putorius furo	75.51	0.00e+00	877.00
IUUC-Nle-069429	Nomascus leucogenys	75.85	0.00e+00	909.00
IUUC-Ont-071780	Oreochromis niloticus	69.26	0.00e+00	741.00
IUUC-Ola-086458	Oryzias latipes	67.27	0.00e+00	759.00
IUUC-Oga-088739	Otolemur garnettii	74.49	0.00e+00	902.00
IUUC-Oar-089275	Ovis aries	80.23	1.00e-41	160.00
IUUC-Ptr-090716	Pan troglodytes	74.90	0.00e+00	728.00
IUUC-Pan-092182	Papio anubis	69.56	0.00e+00	792.00
IUUC-Pma-094289	Petromyzon marinus	52.56	2.00e-175	608.00
IUUC-Pfo-096062	Poecilia formosa	68.77	0.00e+00	750.00
IUUC-Pab-098726	Pongo abelii	74.83	0.00e+00	889.00
IUUC-Pca-100163	Procavia capensis	81.15	1.00e-90	326.00
IUUC-Pva-103051	Pteropus vampyrus	77.57	2.00e-124	439.00
IUUC-Rno-105707	Rattus norvegicus	73.98	0.00e+00	879.00
IUUC-Sha-107074	Sarcophilus harrisii	80.50	0.00e+00	890.00
IUUC-Ssc-116020	Sus scrofa	73.96	0.00e+00	731.00
IUUC-Tgu-116683	Taeniopygia guttata	79.93	6.00e-116	409.00
IUUC-Tru-118143	Takifugu rubripes	67.47	0.00e+00	731.00
IUUC-Tni-120777	Tetraodon nigroviridis	67.92	0.00e+00	738.00
IUUC-Ttr-128439	Tursiops truncatus	73.98	0.00e+00	867.00
IUUC-Xtr-132774	Xenopus tropicalis	56.67	2.00e-151	528.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence