iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071900

Ensembl Protein ID

ENSONIP00000018126.1

UniProt Accession

I3KAI1; I3KAI1_ORENI

Genbank Protein ID

ENSONIP00000018126

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

AERX01025334

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000014418.1	ENSONIT00000018140.1	ENSONIP00000018125.1
ENSONIG00000014418.1	ENSONIT00000018141.1	ENSONIP00000018126.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.20e-12	46.8	693	737

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek.CrewfHpaClklsveeelpnsekwiCpkCr 52
           +vC +C+  g++   l++Ce  C++ fH +Cl+ls   + p+  +++C +Cr
   Q: 693  TVCQICEVYGDG---LMVCEGdCNRQFHMECLGLS---SPPEG-RFTCAECR 737
           79*****99995...*****99*************...55555.4******8 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MDFSFSFMQG IMGNTIQQPP QLIDSANIRQ EGTCDTGSDP GEDGGPSYDA ALDAEFPYPP 60
SASEDMPQVP NGYPPGLGIY EPQAKFSMYS QFPNGSANGY GAIRSYGDHG LIPPPSLVDN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATTTCT CCTTCTCTTT CATGCAAGGG ATCATGGGAA ATACAATTCA GCAACCCCCT 60
CAGCTCATTG ACTCCGCCAA CATCAGACAG GAAGGCACCT GCGACACCGG CAGTGACCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR006560--AWS_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51215--AWS
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00855--PWWP
PF00856--SET

SMART

SM00570--AWS
SM00249--PHD
SM00293--PWWP
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000310	Aegilops tauschii	30.05	1.00e-12	68.90
IUUC-Aml-001809	Ailuropoda melanoleuca	70.76	0.00e+00	1248.00
IUUC-Apl-004027	Anas platyrhynchos	55.69	0.00e+00	1474.00
IUUC-Aca-005380	Anolis carolinensis	58.62	0.00e+00	1539.00
IUUC-Ame-011234	Astyanax mexicanus	66.07	0.00e+00	1598.00
IUUC-Bta-013575	Bos taurus	58.87	0.00e+00	1605.00
IUUC-Bdi-014781	Brachypodium distachyon	30.46	3.00e-12	67.40
IUUC-Bol-016555	Brassica oleracea	32.95	2.00e-14	74.30
IUUC-Bra-017733	Brassica rapa	33.53	2.00e-14	74.70
IUUC-Cja-020013	Callithrix jacchus	60.25	0.00e+00	1707.00
IUUC-Cfa-021060	Canis familiaris	59.59	0.00e+00	1655.00
IUUC-Cpo-021834	Cavia porcellus	59.58	0.00e+00	1601.00
IUUC-Csa-023370	Chlorocebus sabaeus	59.90	0.00e+00	1698.00
IUUC-Cho-025058	Choloepus hoffmanni	79.35	1.00e-127	451.00
IUUC-Dno-029302	Dasypus novemcinctus	60.28	0.00e+00	1663.00
IUUC-Eca-033626	Equus caballus	57.45	0.00e+00	1592.00
IUUC-Fca-035556	Felis catus	59.53	0.00e+00	1668.00
IUUC-Fal-037101	Ficedula albicollis	65.63	0.00e+00	1218.00
IUUC-Gmo-038901	Gadus morhua	77.33	0.00e+00	2106.00
IUUC-Gga-040366	Gallus gallus	57.72	0.00e+00	1508.00
IUUC-Gac-042047	Gasterosteus aculeatus	82.45	0.00e+00	2139.00
IUUC-Ggo-044695	Gorilla gorilla	57.47	0.00e+00	1590.00
IUUC-Hsa-046080	Homo sapiens	59.83	0.00e+00	1692.00
IUUC-Itr-048622	Ictidomys tridecemlineatus	60.10	0.00e+00	1647.00
IUUC-Lch-050544	Latimeria chalumnae	60.73	0.00e+00	1376.00
IUUC-Lpe-051661	Leersia perrieri	29.29	5.00e-14	73.90
IUUC-Loc-052656	Lepisosteus oculatus	68.13	0.00e+00	1668.00
IUUC-Laf-054112	Loxodonta africana	58.32	0.00e+00	1627.00
IUUC-Mcc-054956	Macaca mulatta	59.97	0.00e+00	1701.00
IUUC-Meu-056051	Macropus eugenii	74.50	0.00e+00	851.00
IUUC-Mga-060139	Meleagris gallopavo	58.55	0.00e+00	1551.00
IUUC-Mmr-060789	Microcebus murinus	59.15	0.00e+00	1676.00
IUUC-Mdo-062908	Monodelphis domestica	59.18	0.00e+00	1606.00
IUUC-Mmu-063165	Mus musculus	55.76	0.00e+00	1525.00
IUUC-Mac-065303	Musa acuminata	30.16	3.00e-11	63.90
IUUC-Mpu-066002	Mustela putorius furo	59.57	0.00e+00	1667.00
IUUC-Nle-069417	Nomascus leucogenys	59.17	0.00e+00	1590.00
IUUC-Oan-072857	Ornithorhynchus anatinus	59.18	0.00e+00	1625.00
IUUC-Ocu-073809	Oryctolagus cuniculus	59.68	0.00e+00	1660.00
IUUC-Obr-076178	Oryza brachyantha	29.59	3.00e-12	67.40
IUUC-Ola-087085	Oryzias latipes	82.00	0.00e+00	2244.00
IUUC-Oga-088289	Otolemur garnettii	59.83	0.00e+00	1660.00
IUUC-Oar-089398	Ovis aries	59.93	0.00e+00	1630.00
IUUC-Ptr-090510	Pan troglodytes	59.90	0.00e+00	1697.00
IUUC-Pan-092291	Papio anubis	59.97	0.00e+00	1698.00
IUUC-Psi-093547	Pelodiscus sinensis	59.60	0.00e+00	1610.00
IUUC-Pma-094747	Petromyzon marinus	54.73	0.00e+00	868.00
IUUC-Pfo-096669	Poecilia formosa	82.48	0.00e+00	2262.00
IUUC-Pab-097727	Pongo abelii	59.99	0.00e+00	1696.00
IUUC-Pop-099927	Populus trichocarpa	30.53	4.00e-12	67.00
IUUC-Pca-100474	Procavia capensis	56.13	0.00e+00	1487.00
IUUC-Ppe-101635	Prunus persica	29.90	1.00e-11	65.50
IUUC-Pva-102539	Pteropus vampyrus	71.71	0.00e+00	1248.00
IUUC-Rno-105685	Rattus norvegicus	69.50	0.00e+00	1178.00
IUUC-Sha-107287	Sarcophilus harrisii	58.98	0.00e+00	1594.00
IUUC-Sit-110333	Setaria italica	31.36	5.00e-11	63.20
IUUC-Sar-113547	Sorex araneus	57.44	0.00e+00	1563.00
IUUC-Ssc-116208	Sus scrofa	60.22	0.00e+00	1693.00
IUUC-Tgu-117006	Taeniopygia guttata	58.37	0.00e+00	1576.00
IUUC-Tru-118375	Takifugu rubripes	82.75	0.00e+00	2297.00
IUUC-Tsy-119323	Tarsius syrichta	59.01	0.00e+00	1658.00
IUUC-Tni-120509	Tetraodon nigroviridis	79.81	0.00e+00	2171.00
IUUC-Tae-124687	Triticum aestivum	30.46	1.00e-12	68.60
IUUC-Ttr-128240	Tursiops truncatus	71.24	0.00e+00	1193.00
IUUC-Vpa-130666	Vicugna pacos	58.73	0.00e+00	1626.00
IUUC-Xma-134036	Xiphophorus maculatus	82.20	0.00e+00	2233.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence